5 ms·

I believe in the future it will be basically free to sequence the genome from a strand of hair. Given that, is it reasonable to try protecting your genome data?

mattnewton 8y ago
Imo yes; the ability to match dna to individuals without their consent should belong to law enforcement only. I am holding out hope for legislation that makes this work.
- conception 8y ago
  The ability to match dna to individuals is sadly pretty easy and even the idea that you can "de-identify" dna is the elephant in the room for things like HIPPA since dna is the most identifiable thing a person has. Looking at things like this - https://phys.org/news/2013-03-easy-identity-cell.html https://phys.org/news/2013-03-easy-identity-cell.html https://33bits.wordpress.com/about/ https://33bits.wordpress.com/about/ etc Having DNA and just looking at the traits that person has will reduce the population down to a pretty manageable number. Any other bits - location, gender, etc will be enough to make an educated guess to an almost certain one. This will not become more difficult to do in the future.
  - echelon 8y ago
    I wouldn't be surprised if we trained ML models to map DNA to adult faces. It doesn't seem out of the realm of possibility.
    - m1573rp34130dy 8y ago
      there is a thing called developmental noise, thats the outcome of phenotype after post expressional events further modify the expression products [proteins, RNA, MeDNA etc.] the face you interpolate from genetic sequence will be an approximation.
    - JProthero 8y ago
      A company founded by Craig Venter and Peter Diamandis (Human Longevity Inc) has been working on this and published a paper about it last year in PNAS [1], but it attracted some scepticism from other researchers in the field (the paper was rejected for publication by Science) [2]. [1] http://www.pnas.org/content/early/2017/08/29/1711125114 http://www.pnas.org/content/early/2017/08/29/1711125114 [2] https://www.technologyreview.com/s/608813/does-your-genome-predict-your-face-not-quite-yet/ https://www.technologyreview.com/s/608813/does-your-genome-p...
- goatsi 8y ago
  The biggest issue is relatives. All you need is one person relatively closely related to you to openly post their DNA on a genealogy site and someone searching only has a handful of people to narrow down from.[0] I used 23andme years ago, using a fake name on the website and a kit ordered by someone else (a friend ordered kits). I should see if I can use their GDPR process to purge it before any relatives give it a shot and start a scandal about the presence of John Doe in the family tree. [0] https://globalnews.ca/news/4171752/golden-state-killer-dna-genealogy-website/ https://globalnews.ca/news/4171752/golden-state-killer-dna-g...
amelius 8y ago
Yes, because in the future there will be laws addressing issues surrounding DNA data. Right now, it's the wild west.
Real_S 8y ago
Just because sensitive information can be compromised doesn't mean that it should be offered freely. Yes, someone can target you and collect a DNA sample, but does that mean you shouldn't care how securely your genetic data is used and stored?

mattnewton 8y ago

Imo yes; the ability to match dna to individuals without their consent should belong to law enforcement only. I am holding out hope for legislation that makes this work.

conception 8y ago
The ability to match dna to individuals is sadly pretty easy and even the idea that you can "de-identify" dna is the elephant in the room for things like HIPPA since dna is the most identifiable thing a person has. Looking at things like this - https://phys.org/news/2013-03-easy-identity-cell.html https://phys.org/news/2013-03-easy-identity-cell.html https://33bits.wordpress.com/about/ https://33bits.wordpress.com/about/ etc Having DNA and just looking at the traits that person has will reduce the population down to a pretty manageable number. Any other bits - location, gender, etc will be enough to make an educated guess to an almost certain one. This will not become more difficult to do in the future.
- echelon 8y ago
  I wouldn't be surprised if we trained ML models to map DNA to adult faces. It doesn't seem out of the realm of possibility.
  - m1573rp34130dy 8y ago
    there is a thing called developmental noise, thats the outcome of phenotype after post expressional events further modify the expression products [proteins, RNA, MeDNA etc.] the face you interpolate from genetic sequence will be an approximation.
  - JProthero 8y ago
    A company founded by Craig Venter and Peter Diamandis (Human Longevity Inc) has been working on this and published a paper about it last year in PNAS [1], but it attracted some scepticism from other researchers in the field (the paper was rejected for publication by Science) [2]. [1] http://www.pnas.org/content/early/2017/08/29/1711125114 http://www.pnas.org/content/early/2017/08/29/1711125114 [2] https://www.technologyreview.com/s/608813/does-your-genome-predict-your-face-not-quite-yet/ https://www.technologyreview.com/s/608813/does-your-genome-p...
goatsi 8y ago
The biggest issue is relatives. All you need is one person relatively closely related to you to openly post their DNA on a genealogy site and someone searching only has a handful of people to narrow down from.[0] I used 23andme years ago, using a fake name on the website and a kit ordered by someone else (a friend ordered kits). I should see if I can use their GDPR process to purge it before any relatives give it a shot and start a scandal about the presence of John Doe in the family tree. [0] https://globalnews.ca/news/4171752/golden-state-killer-dna-genealogy-website/ https://globalnews.ca/news/4171752/golden-state-killer-dna-g...

amelius 8y ago

Yes, because in the future there will be laws addressing issues surrounding DNA data. Right now, it's the wild west.

Real_S 8y ago

Just because sensitive information can be compromised doesn't mean that it should be offered freely. Yes, someone can target you and collect a DNA sample, but does that mean you shouldn't care how securely your genetic data is used and stored?