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If you’re in your 30s a much better bet for your overall health and for keeping Alzheimer’s away is giving up on sugar, since there’s a strong link between Alzh

If you’re in your 30s a much better bet for your overall health and for keeping Alzheimer’s away is giving up on sugar, since there’s a strong link between Alzheimer’s and insulin resistance. Exercise too does help a little with insulin resistance (but not enough to repair the damage done by a diet high in sugar), plus people that exercise tend to also eat healthy.

mg74 8y ago
This. STOP EATING SUGAR PEOPLE!
- DamnInteresting 8y ago
  > STOP EATING SUGAR PEOPLE! But sugar people are delicious! They're such sweethearts.
  - overcast 8y ago
    Sour Patch Kids for life <3
  - deleted 8y ago
    [deleted]
- deleted 8y ago
  [deleted]
- zeroxfe 8y ago
  eats shoots and leaves
francisofascii 8y ago
This might be simplistic thinking, but isn't this why exercise helps? The liver turns the fructose from the sugar into glycogen. Exercise consumes the glycogen before it has a chance to be overly abundant, which is what causes the harmful effects. So you can either avoid sugar altogether, or have sugar with sufficient exercise.
- justinator 8y ago
  Yeah, you have a good point. When/while you exercise fructose can be more easily converted to glucose, to be used right away by the body (faster than glucose alone). That's what's meant by, "a higher metabolism" Under rest, 30% of fructose is converted to fat by the liver. https://youtu.be/dBnniua6-oM?t=3873 https://youtu.be/dBnniua6-oM?t=3873 The real reason to exercise (for health) is it improves your skeletal muscle insulin sensitivity - it's certainly not because you burn a ton of calories from the exercise, https://youtu.be/dBnniua6-oM?t=4300 https://youtu.be/dBnniua6-oM?t=4300
- darkerside 8y ago
  As in my other comment, I see more benefit from cutting wheat than sugar. But to your question, keeping your blood sugar low, and then exercising, helps your metabolic flexibility, i.e. your body's ability to generate energy from fat. So the best answer is, do both.
kevin_thibedeau 8y ago
That doesn't implicate sugar any more than excess body fat. There is no established causality from sugar intake. It's just popular to slam on sugar and promote fat acceptance so sugar is the "obvious" demon.
- ecwilson 8y ago
  Can you clarify what you mean? I might have misunderstood you. I was a little flabberghasted that you seemed to say that there's no causality between sugar and insulin resistance. Based on everything I've been reading in the past 10 years, there's very clear causality between insulinogenic foods, insulin resistance, and body fat. The mechanisms, I thought, were also very well understood.
  - justinator 8y ago
    Perhaps they're talking about Alzheimers specifically? If you frame Alzheimers as a disease of affluence (Which is a bit of a stretch, I'll admit), you could look to the same causes (like excess added sugar in industrialized diets)
- jayalpha 8y ago
  There is a link between sugar intake and diabetes. Some people also suggest Alzheimer is a 3rd form of diabetes. I read a study that nasal applied insulin actually helps Alzheimer. So, no slamming of sugar, just some preliminary evidence that may want to ask yourself if you really need to drink a liter or 2 liters of coke per day.
copperx 8y ago
I wonder whether taking Metformin defensively helps in any way to reduce the odds of Alzheimer's if you have metabolic syndrome.
abledon 8y ago
But my brain runs on glucose !
darkerside 8y ago
Much like we used to think dietary fat created visceral fat, and dietary cholesterol created blood cholesterol, we've been operating under the assumption that eating sugar is the primary cause of high blood sugar leading to insulin resistance. When you look at the glycemic index and glycemic load of foods, it's actually wheat that comes out on top. Cutting wheat out of your diet is likely to be much more effective at reducing your insulin resistance, and there are often a litany of other positive health outcomes as well.
- justinator 8y ago
  > Much like we used to think dietary fat created visceral fat, and dietary cholesterol created blood cholestero Those have been debunked. You're running on that same assumption, correct? > we've been operating under the assumption that eating sugar is the primary cause of high blood sugar leading to insulin resistance That's called Type 2 Diabetes. I don't know if that's an assumption? > When you look at the glycemic index and glycemic load of foods, it's actually wheat that comes out on top. Wheat is glucose though, not fructose. Cutting soda out of your diet is probably better than having a naked sandwich. I would say that switching to whole wheat from white bread is a positive, though.
  - darkerside 8y ago
    Sorry if I was unclear, but you seem to have completely misunderstood my post. I hardly know where to start with clarifying. 1. Yes, those have been debunked. That's why I said "used to". 2. Most people assume dietary sugar creates high blood sugar. I'm stating that, like saying dietary fat makes you fat, it sounds intuitive but may not be true. 3. Yes, wheat is glucose. Why do you mention fructose? I didn't. Whole wheat bread will raise your blood sugar, just like white bread. And possibly more than soda. http://quittingsugar.com/2012/07/11/bread-and-coke-smackdown-a-blood-sugar-experiment/ http://quittingsugar.com/2012/07/11/bread-and-coke-smackdown...
    - justinator 8y ago
      > 2. Most people assume dietary sugar creates high blood sugar. > I'm stating that, like saying dietary fat makes you fat, > it sounds intuitive but may not be true. Consuming excess amounts of fructose will (via complicated metabolic pathways) produce a lot of uric acid by your liver. That's what's causing hypertension. This shows the metabolic pathway diagrammed out: https://youtu.be/dBnniua6-oM?t=3395 https://youtu.be/dBnniua6-oM?t=3395 Pretty interesting. Is there a competing theory? > 3. Yes, wheat is glucose. Why do you mention fructose? I didn't. Glucose is not sugar; fructose is. They take different pathways when metabolized. It's true that lots of white bread has added sugar, but that's not the wheat. I would say that if wheat is a silent killer, France would be in big trouble, and they're not.
david-cako 8y ago
I think simple carbohydrates are a much bigger silent evil than even alcohol and opioids. Alcohol and opioids at least have a stigma, and most governments enforce marketing and public health information accordingly. Starch and sugar can never be appropriately demonized because they are "just food", and have some of the largest companies in the US behind them. The advent of processed food has created 2 entire generations of obese, insulin resistant people. The marketing starts as young as possible, and it is normalized to not think twice about eating sugar all day. I'm still trying to get over the fact that the FDA actually banned partially hydrogenated oil. Very surprising that they said no to the entire processed food industry in such a big way, to the benefit of consumers. I'm sure the food conglomerates went into it knowing they had other options like interesterified oils up their sleeves, though.
jesssse 8y ago
Sugar is nutritious for people who have a healthy gut biome.

mg74 8y ago

This. STOP EATING SUGAR PEOPLE!

DamnInteresting 8y ago
> STOP EATING SUGAR PEOPLE! But sugar people are delicious! They're such sweethearts.
- overcast 8y ago
  Sour Patch Kids for life <3
- deleted 8y ago
  [deleted]
deleted 8y ago
[deleted]
zeroxfe 8y ago
eats shoots and leaves

francisofascii 8y ago

This might be simplistic thinking, but isn't this why exercise helps? The liver turns the fructose from the sugar into glycogen. Exercise consumes the glycogen before it has a chance to be overly abundant, which is what causes the harmful effects. So you can either avoid sugar altogether, or have sugar with sufficient exercise.

justinator 8y ago
Yeah, you have a good point. When/while you exercise fructose can be more easily converted to glucose, to be used right away by the body (faster than glucose alone). That's what's meant by, "a higher metabolism" Under rest, 30% of fructose is converted to fat by the liver. https://youtu.be/dBnniua6-oM?t=3873 https://youtu.be/dBnniua6-oM?t=3873 The real reason to exercise (for health) is it improves your skeletal muscle insulin sensitivity - it's certainly not because you burn a ton of calories from the exercise, https://youtu.be/dBnniua6-oM?t=4300 https://youtu.be/dBnniua6-oM?t=4300
darkerside 8y ago
As in my other comment, I see more benefit from cutting wheat than sugar. But to your question, keeping your blood sugar low, and then exercising, helps your metabolic flexibility, i.e. your body's ability to generate energy from fat. So the best answer is, do both.

kevin_thibedeau 8y ago

That doesn't implicate sugar any more than excess body fat. There is no established causality from sugar intake. It's just popular to slam on sugar and promote fat acceptance so sugar is the "obvious" demon.

ecwilson 8y ago
Can you clarify what you mean? I might have misunderstood you. I was a little flabberghasted that you seemed to say that there's no causality between sugar and insulin resistance. Based on everything I've been reading in the past 10 years, there's very clear causality between insulinogenic foods, insulin resistance, and body fat. The mechanisms, I thought, were also very well understood.
- justinator 8y ago
  Perhaps they're talking about Alzheimers specifically? If you frame Alzheimers as a disease of affluence (Which is a bit of a stretch, I'll admit), you could look to the same causes (like excess added sugar in industrialized diets)
jayalpha 8y ago
There is a link between sugar intake and diabetes. Some people also suggest Alzheimer is a 3rd form of diabetes. I read a study that nasal applied insulin actually helps Alzheimer. So, no slamming of sugar, just some preliminary evidence that may want to ask yourself if you really need to drink a liter or 2 liters of coke per day.

copperx 8y ago

I wonder whether taking Metformin defensively helps in any way to reduce the odds of Alzheimer's if you have metabolic syndrome.

abledon 8y ago

But my brain runs on glucose !

darkerside 8y ago

Much like we used to think dietary fat created visceral fat, and dietary cholesterol created blood cholesterol, we've been operating under the assumption that eating sugar is the primary cause of high blood sugar leading to insulin resistance. When you look at the glycemic index and glycemic load of foods, it's actually wheat that comes out on top. Cutting wheat out of your diet is likely to be much more effective at reducing your insulin resistance, and there are often a litany of other positive health outcomes as well.

justinator 8y ago
> Much like we used to think dietary fat created visceral fat, and dietary cholesterol created blood cholestero Those have been debunked. You're running on that same assumption, correct? > we've been operating under the assumption that eating sugar is the primary cause of high blood sugar leading to insulin resistance That's called Type 2 Diabetes. I don't know if that's an assumption? > When you look at the glycemic index and glycemic load of foods, it's actually wheat that comes out on top. Wheat is glucose though, not fructose. Cutting soda out of your diet is probably better than having a naked sandwich. I would say that switching to whole wheat from white bread is a positive, though.
- darkerside 8y ago
  Sorry if I was unclear, but you seem to have completely misunderstood my post. I hardly know where to start with clarifying. 1. Yes, those have been debunked. That's why I said "used to". 2. Most people assume dietary sugar creates high blood sugar. I'm stating that, like saying dietary fat makes you fat, it sounds intuitive but may not be true. 3. Yes, wheat is glucose. Why do you mention fructose? I didn't. Whole wheat bread will raise your blood sugar, just like white bread. And possibly more than soda. http://quittingsugar.com/2012/07/11/bread-and-coke-smackdown-a-blood-sugar-experiment/ http://quittingsugar.com/2012/07/11/bread-and-coke-smackdown...
  - justinator 8y ago
    > 2. Most people assume dietary sugar creates high blood sugar. > I'm stating that, like saying dietary fat makes you fat, > it sounds intuitive but may not be true. Consuming excess amounts of fructose will (via complicated metabolic pathways) produce a lot of uric acid by your liver. That's what's causing hypertension. This shows the metabolic pathway diagrammed out: https://youtu.be/dBnniua6-oM?t=3395 https://youtu.be/dBnniua6-oM?t=3395 Pretty interesting. Is there a competing theory? > 3. Yes, wheat is glucose. Why do you mention fructose? I didn't. Glucose is not sugar; fructose is. They take different pathways when metabolized. It's true that lots of white bread has added sugar, but that's not the wheat. I would say that if wheat is a silent killer, France would be in big trouble, and they're not.

david-cako 8y ago

I think simple carbohydrates are a much bigger silent evil than even alcohol and opioids. Alcohol and opioids at least have a stigma, and most governments enforce marketing and public health information accordingly. Starch and sugar can never be appropriately demonized because they are "just food", and have some of the largest companies in the US behind them. The advent of processed food has created 2 entire generations of obese, insulin resistant people. The marketing starts as young as possible, and it is normalized to not think twice about eating sugar all day. I'm still trying to get over the fact that the FDA actually banned partially hydrogenated oil. Very surprising that they said no to the entire processed food industry in such a big way, to the benefit of consumers. I'm sure the food conglomerates went into it knowing they had other options like interesterified oils up their sleeves, though.

jesssse 8y ago

Sugar is nutritious for people who have a healthy gut biome.