5 ms·

In North Carolina, young Dan Tonkel had taken to wearing a bag of asafetida around his neck, in the belief that the stinking extract would protect him. “It smel

In North Carolina, young Dan Tonkel had taken to wearing a bag of asafetida around his neck, in the belief that the stinking extract would protect him. “It smelled to high heaven,” he recalled. “People thought the smell would kill germs. So we all wore a bag of asafetida and smelled like rotten flesh.” For most of human history, we thought that germs were spread by certain odors. So to counteract them, we would often use aromas: this is why plague doctor masks had the horn which was filled with herbs. EDIT: I meant diseases were thought to be spread by odors, as we didn't yet have a germ theory of disease.

throwawayjava 8y ago
It's fascinating to me how some of these "cures" continue to persist with modernized marketing script. See e.g. some of the claims made about essential oils ([1] contains a concise list for example), many of which were thought to be curative in antiquity mostly because of their powerful aromas:. [1] https://www.fda.gov/iceci/enforcementactions/warningletters/2014/ucm415809.htm https://www.fda.gov/iceci/enforcementactions/warningletters/...
- amelius 8y ago
  The problem is that there are only few controlled trials for herbs and supplements, mainly because there is no money to be made because the substances can't be patented. If company A finances a controlled trial, then company B can just copy the claims. Another problem is that these herbal cures may work initially (through placebo effect or a real mechanism), and then stop working. However, at that point the word has already been spread. This is especially troubling in the internet age, where people post reviews after one day of trying something.
- ben509 8y ago
  There are many quack remedies and elixirs that have been around forever and long ago obtained protected status with government regulators.
the-dude 8y ago
Some aromas keep away insects.
- amelius 8y ago
  Some aromas keep other people away, which can help in containing the disease ...
- delecti 8y ago
  That probably led to just enough effect from these strategies to give people a reason to keep using them.
MrEldritch 8y ago
And the funny thing is, plague doctor masks were actually fairly effective - it turns out that a beak stuffed full of herbs is actually a pretty serviceable medieval-era substitute for a surgical facemask at preventing you from inhaling aerosols.
- gascan 8y ago
  Yeah, it's kind of funny how we arrived at some of the right answers for totally the wrong reasons. The whole "bad air" concept? Total hokum, but an abundance of fresh air will help control airborne transmission.
  - whatshisface 8y ago
    You could argue that the entire human body along with every infections disease got invented in the same way.
  - fjsolwmv 8y ago
    If you realize that experiment generally orecedes theory, it's completely sensible. Experiments are reproducible, theories are abstract. Making could decisions is more useful than having correct explanations.
    - ItsMe000001 8y ago
      > Experiments are reproducible Not nitpicking (at least that's not my intent), just adding: Only if you know what the variables are. This occurred to me because I'm myself an interesting medical case beating even a professor of medicine's prediction, as well as independent ones from various doctors about other things that turned out to be symptoms of the same underlying chronic poisoning issue that I had to diagnose myself, and only then find the right specialist for it. There has been sooo much interesting stuff going on in my body during years of slow recovery (and a few "miracles" that left doctors literally speechless), but I would not be able to say how you could repeat the "experiment". Too little is known about any of what goes on inside me right now, my doctor (researcher at university clinic) has long ago admitted that we left the area of known study-supported medicine behind. I suspect a few mechanisms based on observing myself that I have no way and no idea how to prove. So I'm of course not certain what I can claim, or what exactly happened, but neither would I know how to repeat my personal experiment even if human experiments were possible. It's just too much unknown territory. And in the end my experiences will all be lost, unfortunately. An example for something I suspect: Some diseases like the common cold may not always be orthogonal and superfluous. In my case, over the years, I got more and more the impression that it actively helped my body to get rid of what was stored over decades. I suspect that everything is much more intertwined and connected and not separate. One prediction I could make based on this suspicion is that if we were to be able to eliminate mild diseases like the cold completely we would get more serious diseases or other issues down the road. That's not a practical experiment though, maybe some large-scale observational studies can get some hints one way or the other, but it will be too messy and too uncertain for anything even close to a definite proof or disproof. Another thing I suspect is that even very low level exposure (far below officially allowed levels) to heavy metals has very real consequences - it's just that on an individual basis we are almost utterly unable to show it. We can do it only on a population basis, and we all know how messy that is with all the known and unknown confounders.
theophrastus 8y ago
For most of human history, we thought that germs were spread by certain odors. Yep, hence malaria (bad-air)
brogrammer5 8y ago
Reminds me of that Sanford and Son episode where he wore that to keep from getting sick.
throwaway82729 8y ago
An apple a day keeps the doctor away. An onion a day keeps everybody away.

throwawayjava 8y ago

It's fascinating to me how some of these "cures" continue to persist with modernized marketing script. See e.g. some of the claims made about essential oils ([1] contains a concise list for example), many of which were thought to be curative in antiquity mostly because of their powerful aromas:. [1] https://www.fda.gov/iceci/enforcementactions/warningletters/2014/ucm415809.htm https://www.fda.gov/iceci/enforcementactions/warningletters/...

amelius 8y ago
The problem is that there are only few controlled trials for herbs and supplements, mainly because there is no money to be made because the substances can't be patented. If company A finances a controlled trial, then company B can just copy the claims. Another problem is that these herbal cures may work initially (through placebo effect or a real mechanism), and then stop working. However, at that point the word has already been spread. This is especially troubling in the internet age, where people post reviews after one day of trying something.
ben509 8y ago
There are many quack remedies and elixirs that have been around forever and long ago obtained protected status with government regulators.

the-dude 8y ago

Some aromas keep away insects.

amelius 8y ago
Some aromas keep other people away, which can help in containing the disease ...
delecti 8y ago
That probably led to just enough effect from these strategies to give people a reason to keep using them.

MrEldritch 8y ago

And the funny thing is, plague doctor masks were actually fairly effective - it turns out that a beak stuffed full of herbs is actually a pretty serviceable medieval-era substitute for a surgical facemask at preventing you from inhaling aerosols.

gascan 8y ago
Yeah, it's kind of funny how we arrived at some of the right answers for totally the wrong reasons. The whole "bad air" concept? Total hokum, but an abundance of fresh air will help control airborne transmission.
- whatshisface 8y ago
  You could argue that the entire human body along with every infections disease got invented in the same way.
- fjsolwmv 8y ago
  If you realize that experiment generally orecedes theory, it's completely sensible. Experiments are reproducible, theories are abstract. Making could decisions is more useful than having correct explanations.
  - ItsMe000001 8y ago
    > Experiments are reproducible Not nitpicking (at least that's not my intent), just adding: Only if you know what the variables are. This occurred to me because I'm myself an interesting medical case beating even a professor of medicine's prediction, as well as independent ones from various doctors about other things that turned out to be symptoms of the same underlying chronic poisoning issue that I had to diagnose myself, and only then find the right specialist for it. There has been sooo much interesting stuff going on in my body during years of slow recovery (and a few "miracles" that left doctors literally speechless), but I would not be able to say how you could repeat the "experiment". Too little is known about any of what goes on inside me right now, my doctor (researcher at university clinic) has long ago admitted that we left the area of known study-supported medicine behind. I suspect a few mechanisms based on observing myself that I have no way and no idea how to prove. So I'm of course not certain what I can claim, or what exactly happened, but neither would I know how to repeat my personal experiment even if human experiments were possible. It's just too much unknown territory. And in the end my experiences will all be lost, unfortunately. An example for something I suspect: Some diseases like the common cold may not always be orthogonal and superfluous. In my case, over the years, I got more and more the impression that it actively helped my body to get rid of what was stored over decades. I suspect that everything is much more intertwined and connected and not separate. One prediction I could make based on this suspicion is that if we were to be able to eliminate mild diseases like the cold completely we would get more serious diseases or other issues down the road. That's not a practical experiment though, maybe some large-scale observational studies can get some hints one way or the other, but it will be too messy and too uncertain for anything even close to a definite proof or disproof. Another thing I suspect is that even very low level exposure (far below officially allowed levels) to heavy metals has very real consequences - it's just that on an individual basis we are almost utterly unable to show it. We can do it only on a population basis, and we all know how messy that is with all the known and unknown confounders.

theophrastus 8y ago

For most of human history, we thought that germs were spread by certain odors. Yep, hence malaria (bad-air)

brogrammer5 8y ago

Reminds me of that Sanford and Son episode where he wore that to keep from getting sick.

throwaway82729 8y ago

An apple a day keeps the doctor away. An onion a day keeps everybody away.