3 ms·

Well, to be precise- this study shows no evidence of a fasting effect. they show if you starve cells in a dish in a way that might mimic what happens when you

Well, to be precise- this study shows no evidence of a fasting effect. they show if you starve cells in a dish in a way that might mimic what happens when you fast, you can kill the cells. I didn't see any mention of even mouse studies in there, so I don't know what their in vivo model was but it mostly looks like cell culture to me (apologies if I've missed that). Extrapolating that to humans is extremely hard. For sure a promising result but its pretty preliminary.

randcraw 8y ago
The Guidi and Longo paper isn't a study at all. They're summarizing the work of Obrist et al, 2018: https://www.ncbi.nlm.nih.gov/pubmed/29875130 https://www.ncbi.nlm.nih.gov/pubmed/29875130 Apparently efforts similar to these go back to at least six years. "Metabolic reprogramming: A new paradigm for targeting cisplatin resistant cells" describes a recurring research program that began in 2012 which seeks to impede cancer via restraining oxidative metabolism, though I think their method of blocking cancer cell metabolism may be more selective than starving ALL of the patient's cells. http://grantome.com/grant/NIH/IK2-BX001289-03 http://grantome.com/grant/NIH/IK2-BX001289-03