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From what I understand about biology (which is little), there was no real way this was ever going to work. Am I missing something?
by kemiller2002 8y ago
From what I understand about biology (which is little), there was no real way this was ever going to work. Am I missing something?
- deleted 8y ago[deleted]
- amacbride 8y agoWhat they promised is theoretically possible, but they ran afoul of the huge practical problems that made people with actual biology and engineering backgrounds (like myself) very, very skeptical.
- amacbride 8y ago(Oh, and massive financial shenanigans.)
- dnautics 8y agoit's not theoretically possible, due to the statistics of small numbers. You can resolve the nanotainer problem by collecting many of them, but by the time you can measure a statistical difference, you might as well have collected a large volume of blood in the first place.
- petra 8y agoI agree that analyzing small volumes of blood is theoretically possible , but afaik it's yet unclear that you can get good samples from blood drawn from fingers, because it's mixed with interstitial fluid.
- dekhn 8y agoThere is no reason the underlying idea of nanotainers being used for blood analysis is fundamentally impossible but it is a hard problem because the volume of blood is so small there can easily be statistical fluctuations that affect the classifier. That said, it's strictly correct that, if engineered properly, it could have provided additional actionable medical data.
- dnautics 8y ago> There is no reason the underlying idea of nanotainers being used for blood analysis is fundamentally impossible but it is a hard problem because the volume of blood is so small there can easily be statistical fluctuations that affect the classifier. Do you not see how the second half of this statement strictly contradicts the first?
- dekhn 8y agoHey, um, I've got a PhD in Biophysics, I've worked with biology, and I've got 20+ years experience in the field. The VC I advise declined to fund theranos for this very reason. That said, everything I know about biophysics and building classifiers (something I do for a large company known for machine learning) says that it's still technically possible to provide actionable medical data from tiny volumes of blood. It does not "strictly contradict".
- meowface 8y agoDifficult doesn't mean impossible.