2 ms·

With all due respect, dosing schedule and biological half life have little to do with the addictive potential of oxycodone. Put simply, it lights up the brain's

With all due respect, dosing schedule and biological half life have little to do with the addictive potential of oxycodone. Put simply, it lights up the brain's reward center like a Christmas tree. If you dig, you can find studies that show that oxycodone causes a far greater dopamine release in the nucleus accumbens than even IV heroin. This has been known for a long time. The people who developed oxycodone knew what they were doing - engineering the most addictive opiate on the market. Purdue really needs to be held accountable for what they've done and the lives they've ruined and/or ended. The blame for the opioid epidemic falls squarely on them, in my opinion.

SmellTheGlove 9y ago
It's scary good. I've had it prescribed to me twice - once when I had my wisdom teeth out (a fairly significant surgery, they were bony impacted) and again when I had a hernia repaired. Both were 5mg, 30 pills. I took 'em all. This was years ago, but I still remember to this day _exactly_ how good they made me feel. Scary stuff, I'll never fill a prescription for these again, I don't give a shit what I have going on.
- msmm 9y ago
  When I had my wisdom tooth out I was told to take paracetamol. I didn't need to because pain was bearable and was gone next day.