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Hm. Parkinson's patients sometimes have tremors, but all tremors are not Parkinson's. The physiological explanation of Parkinson's "firing off wrong signals t
by caycep 9y ago
Hm.
Parkinson's patients sometimes have tremors, but all tremors are not Parkinson's. The physiological explanation of Parkinson's "firing off wrong signals to muscles" is not correct.
Parkinson's disease is defined primarily by bradykinesia and limb rigidity - the difficulty of the motor planning part of the brain processing motor commands to the motor cortex. Much of the disability in Parkinson's disease comes from a patient's brain not being able to come up with motor commands fast enough, resulting in wooden, statue-like movement and gait instability (i.e. coming up with motor commands fast enough to maintain upright balance).
Of interest - while tremors (i.e. essential tremors, action tremors, rubral tremors) can limit function, the interesting part of Parkinsonian tremors are that the vast majority of them are "resting tremors," i.e. they go away with action and thus are not the limiting factor of writing. Most Parkinson's patients complain, rather, of the bradykinesia (motor command issues) causing micrographia, or excessively small and unreadable handwriting.
Anyway, I am not sure what diagnosis Emma actually has - it may be what is known as a "tremor predominant" Parkinson's disease (which overlaps a bit with essential tremor, another neurological movement disorder). It may very well be essential tremor. Or it may be a dystonic tremor which responds, bizarrely, to weird sensory cues, i.e. "gestes antagonistes". If the watch with its vibrating counterweights works for her, great. For most of our Parkinson's patients, it doesn't solve their main issue which is the inability to move or walk, or at least do so well.
Not to mention the cognitive deficits in Parkinson's disease which is a whole other can of worms.
Of note: Parkinsonian and essential tremors respond extremely well to implantable deep brain stimulators...that is a whole other topic as well.
- bsg75 9y agoDoes the article even mention if the watch has any active vibration adjustment? I may have missed it, but I'm wondering if this is a specific vibration pattern, or if any similar vibrations would help this particular person.
- caycep 9y agoI think it was buried deep in there somehow, but I didn't really see a great explanation of what exactly they were doing. TBH there seems to be a ton of "wearables" ideas flooding the poster sessions of the last few Movement Disorders Congresses, but honestly, these all either a) focus on tremor tracking to the exclusion of everything else and thus totally misses the main point of Parkinson's, or b) pour a ton of money onto custom hardware and electronics, yet can't really accomplish more than what you get with a fitbit or Apple Watch,
- kylixz 9y agoAre you in some way working with those with Parkinson's? You seem highly knowledgeable. I have a relative that I believe is in denial of the disease (Parkinson's + as described by one doctor) and am looking for some insight. Apologies for the out of band comment, just looking for help.
- caycep 9y agoHm, sure. Not sure what the best way to get in touch would be through HN, but send an email to my username at gmail i guess.