5 ms·
> 8.0–31.2 g per day That is surprising amount of aspirin.
by benji-york 9y ago
> 8.0–31.2 g per day
That is surprising amount of aspirin.
- jszymborski 9y agoyou know what they say, ten aspirin tablets a-day keeps the emergency room busy.
- Reason077 9y agoEven a small amount of Asprin, if taken regularly, will mess up your stomach in my experience! I guess not everyone is sensitive to it, but for me I've avoided Asprin (and Ibuprofen, another NSAID drug) for years because of this.
- mixmastamyk 9y agoI come from a long line of iron-stomachs who don't bat an eyelash at any of those. ;)
- mod 9y agoWhat's 'regular?' I use ibprufen exclusively, without stomach issues. But not daily. I probably take it once per week on average. Usually when lacking caffeine has caused a headache. Or eyestrain, occasionally. Those are probably the issues I should fix, though.
- oxide 9y ago>But not daily. I probably take it once per week on average. My grandmother shits and pukes blood if she takes NSAIDs of any kind, from long-term, daily misuse. I'm not exaggerating even a little bit, I wish I was. A direct result of being denied access to proper pain relief, mind you, mainly because she lived her entire life without health insurance. Until she turned 65 and qualified for Medicare last year. I had to take every NSAID out of the house, and throw them away, because every time she ran out of opiates for pain relief she'd over-compensate with a handful of NSAIDs which resulted in some scary events, including coffee ground bowel movements which were in fact blood from her stomach. As well as constant vomiting, etc. My grandfather is similarly damaged from being recklessly over-prescribed NSAIDs, namely 800mg ibuprofen up to 8 times per day, resulting in shitting and puking up blood. He can't have more than an 81mg aspirin now. /anecdotal evidence
- taneq 9y agoAfter surgery I was prescribed an NSAID called Naproxen. It's apparently much easier on the stomach than Ibuprofen, but has a very slightly higher chance of causing a heart attack or stroke. I think this is one of those situations where they'd rather a thousand people be miserable and wreck their stomachs than one person drop dead and cause a lawsuit.
- maccard 9y agoAdd me to the anecdotal evidence there. A regular dose of ibuprofen and I can't eat and I throw up blood for a day..
- thescriptkiddie 9y agoAre you taking it with food? Because ibuprofen absolutely will cause GI bleeding if you take it without food, and yet most of the time there is no label on the bottle to warn you about this.
- biofox 9y agoSame here. I had an acute bleed from using NSAIDs, lost consciousness and came within an inch of dying. I now get extremely emotional when I see articles or comments recommending them without any disclaimer. There's a dangerous misconception that they are harmless (or even health promoting) if used at low / moderate doses.
- gilbetron 9y agoIn the peak of my "strenuous exercise" and "age" graph, I was taking about 12 advil a day, with Zantac. Eventually that, combined with a bit too much drinking (0-3 drinks a day), culminated in a messed up stomach. But I easily can go 2-4 advil a day without a problem. I avoid it, these days, and typically take 1 or 2 every day or two. In the military, "Vitamin M" (800mg of motrin/ibuprofen, about 4 advil) used to be heavily given for about anything multiple times per day!
- copperx 9y agoThat's a bit scary. Chronic use of NSAIDs has been associated with kidney cancer, and if that doesn't scare you, erectile dysfunction may, if you're a man. I'd go with Tylenol instead (carefully), although that has pretty serious liver risks too.
- gilbetron 9y agoI've stopped taking either unless I have a strong reason. No more chronic use at all - yoga does more for pain relief long term, and I stopped playing soccer, and limit myself to lower impact sports. I'm sore enough after exercising without some 20 year asshole laying me out on the field ;)
- maccard 9y agoI had some back problems and was reliant on ibuprofen for a few years. By the time I stopped taking them, I had to choose between back pain/ not being able to walk, or throwing up blood and not being able to eat.
- protomyth 9y agoGiven the doctors seem to be telling everyone over 50 to take a daily aspirin, I would think that a goodly chunk of people aren't sensitive. It might be the low dose people are taking.
- jlamberts 9y agoIt's also possible that the heart benefits outweigh the side effects. A lot of medicine is just saying "this sucks but if you don't do it you'll die" and prescribing the least bad option.
- CWuestefeld 9y agoAs a Crohn's Disease patient, my GI doc advises me to avoid aspirin and Ibuprofen because of their effect on the digestive system. Acetaminophen is fine for this, but apparently requires some care itself because large doses can damage the liver.
- salmonet 9y agoI would go out on a limb and say it's a LOT of Asprin. I usually use "surprising" on HN because anything more specific gets criticized surprisingly often, but that is a ton of asprin
- oxide 9y agoit's a veritable fuck-ton. the usual modern dose is 325mg.
- joelthelion 9y agoIn the US. It's higher in France, for example.
- libdong 9y agoThe maximum daily dose is usually around 4g. 325mg is probably the dose in one tablet.
- joshgel 9y agoDoctor here: very rarely does any prescribe anything more than 325mg daily. Most people get 81mg daily. 325mg is considered high dose. You are correct that it can be written for more, but the only indication you would prescribe a higher dose is as a pain or fever reducer, and we have more effective NSAIDs for that. Or tylenol (?NSAID). I've personally never seen it given more than 325mg daily.