3 ms·

Can young animal blood also make old humans smarter (sheep, goats, pigs, ...)? If so, and without adverse effects [1], an opportunity is discovered. Human cel

Can young animal blood also make old humans smarter (sheep, goats, pigs, ...)? If so, and without adverse effects [1], an opportunity is discovered. Human cells might be better but a protein from animals might be cheaper and less ethically challenged, thus more accessible to the masses. [1] An expert please have a say whether that is plausible or not.

patall 10y ago
Well, antithrombin III is produced in goats [1], although it seems generally more effiecent [2] to produce recombinant proteins in pigs as they are closer related to us. Note, that these are recombinant proteins (human proteins produced in animals) not natural animal proteins that are used in humans. Also note that it might be sufficient to produce these proteins in another biological system like insulin in bacteria (which are easier to handle, carrier lower disease risks, better to scale etc.), it really depends on the complexity of the protein. [1] https://en.wikipedia.org/wiki/Antithrombinhttps://en.wikipedia.org/wiki/Antithrombin https://en.wikipedia.org/wiki/Antithrombinhttps://en.wikiped... [2] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3925420/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3925420/
trevyn 10y ago
You may be interested in: https://en.wikipedia.org/wiki/Cerebrolysin https://en.wikipedia.org/wiki/Cerebrolysin
crusso 10y ago
Maybe, like in the mice studies, we could just graft baby goats to our backs after we hit 50. Sure, it will look odd, but that will just be the price to pay to stay young. The real trick will be to keep the goats from chewing on your shirt collars.
- CleaveIt2Beaver 10y ago
  I feel like this is the entry point to a new piece of dark speculative fiction, in which extreme age is venerated, and the number of goats attached to your back becomes a symbol of your wealth and power.
  - throwaway55523 10y ago
    Perhaps a larger animal. Detachable coupling of course and some sort of programmatic control of the beast. The coupling would include devices which would increase the concentration of life giving material and turn back less desirable properties of the blood. I would ride upon a great blood engorged elephant and take pity upon all the unwashed goat tethered masses.
    - jonnathanson 10y ago
      I storm through the seas like Poseidon himself, a conquering champion, grafted to the back of a 24-foot baby blue whale. Next time around, though, I'll ask the doc to position me in front of the blow hole. Rookie mistake.
- aangjie 10y ago
  > The real trick will be to keep the goats from chewing on your shirt collars. That's easy. Duct tape it solves everything.. Or you can genetically engineer a goat without a mouth. :-)
  - mrkgnao 10y ago
    "I Have No Mouth, and I Must Bleed"?

patall 10y ago

Well, antithrombin III is produced in goats [1], although it seems generally more effiecent [2] to produce recombinant proteins in pigs as they are closer related to us. Note, that these are recombinant proteins (human proteins produced in animals) not natural animal proteins that are used in humans. Also note that it might be sufficient to produce these proteins in another biological system like insulin in bacteria (which are easier to handle, carrier lower disease risks, better to scale etc.), it really depends on the complexity of the protein. [1] https://en.wikipedia.org/wiki/Antithrombinhttps://en.wikipedia.org/wiki/Antithrombin https://en.wikipedia.org/wiki/Antithrombinhttps://en.wikiped... [2] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3925420/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3925420/

trevyn 10y ago

You may be interested in: https://en.wikipedia.org/wiki/Cerebrolysin https://en.wikipedia.org/wiki/Cerebrolysin

crusso 10y ago

Maybe, like in the mice studies, we could just graft baby goats to our backs after we hit 50. Sure, it will look odd, but that will just be the price to pay to stay young. The real trick will be to keep the goats from chewing on your shirt collars.

CleaveIt2Beaver 10y ago
I feel like this is the entry point to a new piece of dark speculative fiction, in which extreme age is venerated, and the number of goats attached to your back becomes a symbol of your wealth and power.
- throwaway55523 10y ago
  Perhaps a larger animal. Detachable coupling of course and some sort of programmatic control of the beast. The coupling would include devices which would increase the concentration of life giving material and turn back less desirable properties of the blood. I would ride upon a great blood engorged elephant and take pity upon all the unwashed goat tethered masses.
  - jonnathanson 10y ago
    I storm through the seas like Poseidon himself, a conquering champion, grafted to the back of a 24-foot baby blue whale. Next time around, though, I'll ask the doc to position me in front of the blow hole. Rookie mistake.
aangjie 10y ago
> The real trick will be to keep the goats from chewing on your shirt collars. That's easy. Duct tape it solves everything.. Or you can genetically engineer a goat without a mouth. :-)
- mrkgnao 10y ago
  "I Have No Mouth, and I Must Bleed"?