5 ms·
> This effect was shown mediated by heat shock proteins (hsps), which are very robustly increased in humans during sauna use. Are they specifically heat relate
by maga 10y ago
> This effect was shown mediated by heat shock proteins (hsps), which are very robustly increased in humans during sauna use.
Are they specifically heat related or any temperature stress might do?
I've been using cold water exclusively year round for last few years with occasional show/ice baths in winter time. I'm wondering if I'm missing something by avoiding warm water/saunas.
- aroch 10y agoHeat shock proteins are really a response to abnormal protein folding (generally speaking) and are found upregulated in a number of stress response scenarios; including cold, heat, and oxidative stress
- pbhjpbhj 10y agoSounds like desert dwellers should live longer? Re oxidative stress, can you give practical examples of how this is achieved for a person, what physical action creates it? https://en.m.wikipedia.org/wiki/Oxidative_stress https://en.m.wikipedia.org/wiki/Oxidative_stress suggests it's associated with lots of great harms - brain diseases, heart disease, etc.. How does that pair with longevity in practice?
- coldtea 10y ago>How does that pair with longevity in practice? It doesn't. It pairs with shock proteins.