"they're suggesting that these different variants are actually proteins of unrelated function....it's a novel claim." Actually, that's old news, too. The only

"they're suggesting that these different variants are actually proteins of unrelated function....it's a novel claim." Actually, that's old news, too. The only thing new here is that they're talking about a paper that did a large-scale analysis of the phenomenon. From the paper's [1] abstract: "While alternative splicing is known to diversify the functional characteristics of some genes, the extent to which protein isoforms globally contribute to functional complexity on a proteomic scale remains unknown. To address this systematically, we..." That said, I look forward to the day when the mass-media discovers glycosylation and other forms of post-translational modification, and writes the next article in this series on How Scientists Had It Wrong All Along (tm). [1] http://www.sciencedirect.com/science/article/pii/S0092867416300435 http://www.sciencedirect.com/science/article/pii/S0092867416...