yshrestha

8 ms·

31.
by yshrestha 4y ago
Good observation. Code is also a Jenga tower of abstractions from High level language (Python) -> Low level language (Assembly) -> CPU microcode. No code is just yet another layer on top. The higher up you go, the more difficult it ca
32.
by yshrestha 4y ago
Yes. Software engineering is just a tool. The risk to society comes when the application of the tool can cause harm. Quantifying and publishing standards to control these risk is best left to experts in the field of application to figure ou
33.
by yshrestha 4y ago
VMs and Docker are just convenient ways to capture the "execution environment" as I referenced in my previous comment.
34.
by yshrestha 4y ago
I think you are mixing the levels of abstraction here. * Physicians apply the scientific method to medicine * Electricians apply construction techniques to electrical construction * Lawyers apply logic and reason to legal problems for a cer
35.
by yshrestha 4y ago
You need two things to run a piece of code: 1) Code and execution environment 2) Compute infrastructure to run (1) on Serverless, to me, means that (2) is abstracted away from you. You submit (1) to the serverless service (AWS Lambda for ex
36.
Nvidia’s New AI: Beautiful Simulations, Cheaper(youtube.com)
2 points by yshrestha 4y ago|0 comments
37.
by yshrestha 4y ago
That is a pretty scary side effect and why AI in medicine needs to be handled carefully, especially anything with generative capability. I do think, however, the primary application of these newer generation of generative models will be use
38.
by yshrestha 4y ago
I am PM, PO, tech lead, and sometimes primary IC on several projects. I am also owner of a software consulting company so I also control budgets and customer relations. When (not if) projects go over my general strategy is to: 1) Take the p
39.
by yshrestha 4y ago
I have the same problem. Rather than fight it, use it as your superpower. I find it helps me write easier to understand abstractions because I can't physically hold enough in my head to understand anything more complex. Same is true fo
40.
by yshrestha 4y ago
How is 2 years flipping a house?
41.
by yshrestha 4y ago
Full disclosure: I am the seller I was on the fence on posting it on HN but I would have totally jumped on the rare combination of gigabit internet, land, animals, and accessory structures if I had known about it. I work remotely and always
42.
Gigabit Homestead(zillow.com)
3 points by yshrestha 4y ago|3 comments
43.
by yshrestha 4y ago
Been working as a consultant and engineer on FDA regulated software for about 8 years now. I have seen strategies from startups to huge companies. I have seen requirements captured in markdown files, spreadsheets, ticket management systems
44.
Nvidia Canvas(nvidia.com)
1 points by yshrestha 5y ago|0 comments
45.
by yshrestha 5y ago
I have been a software consultant for 8 years now so I have a bit of experience to back up my suggestion. Talking to clients did not come easy for me and takes practice just like any other skill. You will learn from experience but I wish I
46.
by yshrestha 5y ago
I have a Moonlander keyboard. Here is my layout: https://configure.zsa.io/moonlander/layouts/wEX6q/latest/0 Anyone care to share theirs?
47.
by yshrestha 5y ago
We are 12 (and hiring). All engineers. Each of our client projects only need 2-3 engineers. We specialize in software only medical devices. Engineers handle the design controls with input from product owners. We even got a product implement
48.
Figjam(figma.com)
1 points by yshrestha 5y ago|0 comments
49.
by yshrestha 6y ago
I found this to be a very interesting take of Earth's history from birth to death.
50.
Watching the End of the World [video](youtube.com)
3 points by yshrestha 6y ago|1 comments
51.
by yshrestha 6y ago
Innolitics | Senior Full Stack Software Engineer | Full time REMOTE We are a tightly knit group of engineers working to make a difference in patients lives through medical device software development. We are obsessed with code quality and t
52.
by yshrestha 6y ago
1) AFIAK there are no hard and set rules for this. I think this would have to be the manufacturer's judgement call. Good point though, with enough time you may end up just over-fitting to the test set. 2) The FDA's guidance on ML
53.
by yshrestha 6y ago
I agree risk management should start at the patient and work backwards to the individual units that themselves can be inputs into an FMEA. When the design gets a bit further along, you can perform an FMEA and repeat the process several tim
54.
by yshrestha 6y ago
Good point. My cognitive bias towards SaMDs is standing out here. I am going to borrow your example of what a "configuration" is, if you don't mind.
55.
by yshrestha 6y ago
I am not articulating myself correctly :) As far as regulatory submissions go and the design outputs that get stored in your QMS, the SDLC appears waterfall because there are clearly defined design inputs, design outputs, and verification &
56.
by yshrestha 6y ago
Regulatory requirements usually does box you into a waterfall sdlc. However, that does not stop you from practicing an iterative sdlc internally. I like to conceptualize it as having a "waterfall shell with an iterative core" It i
57.
by yshrestha 6y ago
Thank you for sharing. These are awesome AI nuggets. In particular, I can relate to the author's suggestion to "visualize everything."
58.
by yshrestha 6y ago
Agreed. The standards are designed to be impervious to time and the implementations used. This has the unfortunate consequence of being quite abstract and difficult to grasp at first. For example "configuration management" was mea
59.
by yshrestha 6y ago
Interesting. I do agree 62304 seems to mostly codify what we would consider best software principles anyway. Your statement about 14971 being the big shift in thinking is interesting. With a bit of clinical context, do you think developers
60.
How we develop FDA-compliant machine learning algorithms(innolitics.com)
58 points by yshrestha 6y ago|36 comments

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