waiquoo

10 ms·

1. 61.▲
   by waiquoo 12y ago

   Winston Timp has done some interesting work in this area ( http://www.sciencedirect.com/science/article/pii/S0006349512... ). Basically, by training a hidden Markov Model, you can get the most likely sequence f
2. 62.▲
   by waiquoo 12y ago

   There are a number of ways to handle that problem. You could melt the DNA or denature it in a basic solution. In some nanopore designs, the diameter of the nanopore is so small that when the DNA is pulled through, only a single strand can p
3. 63.▲
   by waiquoo 12y ago

   Researcher working on a different approach to nanopore sequencing here. The Minion is really interesting technology, but early reports basically indicate that it's essentially useless in it's current form. One of the issues is tha
4. 64.▲
   by waiquoo 12y ago

   I would like to see what the real raw data looks like. There doesn't look to be any noise in that wiggle plot and the signal has already been processed to a degree (see the hard edges and squareness of the features). That's really
5. 65.▲
   by waiquoo 13y ago

   I'll add you to my list of contacts that may be interested testing down the road, no problem
6. 66.▲
   by waiquoo 13y ago

   Fantastic, we are currently finishing up some of the basic research. After wrapping that up, we will be searching for the funding source/incubator that offers the best fit. I know one of the founders of one of your portfolio companies
7. 67.▲
   by waiquoo 13y ago

   We aren't looking for collaborators at the moment, everything is pretty much in house. Once we have an actual shippable, packaged product, we will need collaborators for testing.
8. 68.▲
   by waiquoo 13y ago

   I'm working on the genomic sequencing problem at a hardware level (actually, it's pretty cool, I just got the prototype working and no one else has anything close in terms of transduction mechanism or fundamental stability). What
9. 69.▲
   by waiquoo 13y ago

   see my comment history...
10. 70.▲
    by waiquoo 13y ago

    ha, wasn't me
11. 71.▲
    by waiquoo 13y ago

    https://en.wikipedia.org/wiki/Project_Thor#Project_Thor
12. 72.▲
    by waiquoo 13y ago

    I realized that worthwhile is a vague term when I wrote it. I would say that making $2.35 over 4 days is not worthwhile, but maybe $20/day (beer money) would be reasonable (considering I would not be paying for electricity). More to th
13. 73.▲
    by waiquoo 13y ago

    I don't plan on it, haha. I was more curious. Besides if I got banned from the cluster I would have to drop out of my program.
14. 74.▲
    by waiquoo 13y ago

    Interesting, I have access to a university cluster (in the top 100 of the top500) and I had played with the idea of using it in a similar way. I didn't actually implement it because I need to maintain good terms with the IT dept for my
15. 75.▲
    by waiquoo 13y ago

    As a grad student in a related field, I would love to hear more about semiconductor/hardware startups.
16. 76.▲
    by waiquoo 14y ago

    "Forget reading, we have the ability to write"
17. 77.▲
    by waiquoo 14y ago

    Ion torrent appears to be the same platform as 454, but with detection via chemical means (ISFETs) rather than optical transduction. One of the big drawbacks of the 454 technology that doesn't get talked about a lot is that the immulsion PC
18. 78.▲
    by waiquoo 14y ago

    Hi gourneau, I'm a grad student working on the hardware side of nanopore sequencing. Do you know anything about opportunities in nanofabrication/system design? Or does Dr. Rothberg come up with these things all on his own?