vikramkr

42 ms·

601.
by vikramkr 6y ago
This research is as terrific as it is terrifying. These are some terrific insights into the evolution of intelligence. I doubt that it was one gene alone that drove the whole thing, but as the article mentions, the ethical dilemmas already
602.
by vikramkr 6y ago
I dont think the poll should show the options in random order considering they're ordered in terms of frequency, it makes for a confusing setup
603.
by vikramkr 6y ago
Before I get to comments on the meta information of this article - I'll just point out that the article is complete hyperbole, CRISPR is being used in the clinic, thats not the only metric by which to declare "crispr is dead"
604.
by vikramkr 6y ago
The problem with synthetic bio is that it's going to be pretty hard to drag synbio people away from boston, and I don't think the NIH is leaving bethesda any time soon. I guess my comment is pretty scattered rereading it now - I g
605.
by vikramkr 6y ago
I'm not understanding what you're suggesting. What is a "synthetic biology facility" (research center? Manufacturing plant?), who is paying for them, why are there no jobs, why are they in red states, and since when did
606.
by vikramkr 6y ago
I'm not sure how, but I think you've managed to find the worst possible example to rhetorically support the idea that poverty level people should be punished for VC behavior or even try and claim that it is a tough problem with mo
607.
by vikramkr 6y ago
Find a way to do it keeping the same contractors and adding a couple in some states with senators and representatives who are simultaneously members of the majority party and vulnerable, then maybe you've got a bill, though it might st
608.
by vikramkr 6y ago
If you think it's the last major gasp, you're gonna find yourself awful disappointed. One does not simply kill a jobs program. There'll be SLS, and then some other 2 trillion dollar airplane, then some satellite system, and
609.
by vikramkr 6y ago
Is this one of those cases where the free tier has only public presentations but the paid tier lets you have private presentations?
610.
by vikramkr 6y ago
Make that 2. I knew about the effect for years before I learned who she was.
611.
by vikramkr 6y ago
Yes it will. A big part of the argument for caste comes from some ridiculous traditionalist sentiment that it's a part of "Indian culture" (whatever that is). Changing the sentiment is hard, but pointing out that pre-colonial
612.
by vikramkr 6y ago
That I don't doubt. That's also not unique to India (just think about how many people only marry within their church). The discrimination comes in with the formation of the "untouchable" caste and determination of social
613.
by vikramkr 6y ago
A large portion of the population in south indian states don't have surnames. I think I'm the first person in my family line in what must be centuries that has the same second name as my father (so what you would consider a "
614.
by vikramkr 6y ago
Edit: before downvoting the comment I'm replying to - this is actually a pretty well known scholarly thing - not a fringe conspiracy theory. The British created a legal system that crystallized caste into law using their own interpreta
615.
by vikramkr 6y ago
In cases like this where marketplace efficiency is aligned with moral good, I think we should embrace using it as a tool/weapon to accomplish the moral good. You've got to use the tools you got, and I don't see using capitali
616.
by vikramkr 6y ago
Caste is a thing plenty of Indians are willing to come out and condemn too. My line is pretty simple. Is it a tradition that involves harm being done to an individual without their consent? Then I'm not honoring it. Is it a tradition i
617.
by vikramkr 6y ago
Its a shame that people insist on dragging their prejudices halfway across the world instead of leaving them behind - just human nature I guess. Im glad there's litigation happening now. Drag it to the surface and expose it so we can k
618.
by vikramkr 6y ago
Sure, people have been saying that for a while now and it hasn't materialized. What exactly is going to change that is going to make crypto able to be used like fiat currency? What exactly is in the works thats going to make that happe
619.
by vikramkr 6y ago
Don't worry, we have now identified tau tangles. This must be the root cause, since it is unfathomable that a complex neurodegenerative disease could have complex causes. Now that we have identified [insert misfolded protein candidate
620.
by vikramkr 6y ago
We've got tons of clinical trials going on. None of them have worked so far, but nevertheless, we spend billions experimenting on humans, and trials are always looking for volunteers
621.
by vikramkr 6y ago
Lifespan is a general problem with aging disorders. These studies take forever to run and cost so much, but we pour the money in anyway. Theres definitely some work with nonhuman primates - but with the brain no model is really that great.
622.
by vikramkr 6y ago
Well, I didn't avoid the flames entirely. I singed myself a bit with the second article I linked. You might enjoy it if you haven't already read it
623.
by vikramkr 6y ago
Its like cancer research in the 70s. Lots of money focused on a couple of areas of drug development (like chemo), but the real progress is going to come from long term, deep mechanistic research. We spent so much money on cancer treatments
624.
by vikramkr 6y ago
The statement you quoted should not have been stated so confidently in the article. That statement is the "amyloid hypothesis," and is approximately the equivalent of saying "computer scientists have conclusively determined t
625.
by vikramkr 6y ago
Exciting work, but mouse models of alzheimers are uniquely bad, even among mouse models. Mice don't get alzheimers, and the mechanisms by which we induce alzheimers-like conditions in mice are not analogous to human alzheimers. This mo
626.
by vikramkr 6y ago
I would advise the opposite, especially 3 blue 1 brown. I think getting the intuition first before diving into the deep proofs gives you a north star so you know where proofs will be taking you. I believe that for most people, getting the i
627.
by vikramkr 6y ago
no sanctions may[0] be equally effective as sanctions. [0] https://www.wto.org/english/res_e/reser_e/ersd201803_e.pdf The literature isn't conclusive either way, there's evidence in both directions.
628.
by vikramkr 6y ago
Yeah. - I dont know what that was supposed to accomplish. Its not like the author didn't have enough animal namespace left...
629.
by vikramkr 6y ago
When I think busywork, I think work given to me to occupy my time by someone (probably a teacher or a manager) that has no actual use other than timewasting. Theres this thread of being an externally administered task to my understanding of
630.
by vikramkr 6y ago
Cryo-EM is such a powerful and important tool in biochemistry that any advancement is bound to have significant impacts. Its difficult to overstate how powerful a tool this is and how widely used it is to understand protein structures. Esse

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