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vikramkr
searching PlanetScale…
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451.
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vikramkr
3y ago
That's still just the value of what the collectors market will pay. You down own a share in MLB with the card
452.
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vikramkr
3y ago
Mscs are just a type of multipotent stem cell, and iPSCs can be differentiated into them. For any of the msc therapies today though you won't use iPSCs, you'll just get mscs directly from adipose tissue
453.
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vikramkr
3y ago
That is going to wreck your microbiome and if you aren't taking full dosages to kill everything each time you massively increase the already elevated risk of antibiotic resistance. Don't do this and if you're doing this defin
454.
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vikramkr
3y ago
I think that's why the parent comment was using the word "should" a lot
455.
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vikramkr
3y ago
I think you're referring to a different type of stem cells, multipotent stem cells like mesenchymal cells or hematopoietic cells. iPSCs aren't used in a process like that at this time
456.
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vikramkr
3y ago
I was responding to the article which focused really heavily on therapeutic applications, hence my focus in the last paragraph there
457.
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vikramkr
3y ago
Tried to provide a rough summary, hopefully it's helpful: https://news.ycombinator.com/item?id=37287128
458.
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vikramkr
3y ago
Very cool research! The title is poorly worded, so the quick summary is that we've known how to create stem cells (induced pluripotent stem cells, or iPSCs) from non-stem human cells for a while, but they aren't as "good"
459.
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vikramkr
3y ago
Are apps actually still that important? Id be surprised if more than a low single digit of new webapp projects would want to develop an app at some point instead of just having a mobile optimized website. Especially b2b
460.
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vikramkr
3y ago
Pendulum is probably way sharper this time around because we're dealing with the aftermath of the crypto fallout. Sure in practice this time there are actual applications and lots of people paying actual money for real products, but te
461.
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vikramkr
3y ago
You know whether or not it's warranted before you run the test. That's the whole point of the discussion around when preventative testing is appropriate. The key is that the test is just one additional data point. Before running t
462.
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vikramkr
3y ago
The point is that if you know the test has so many false positives that you're going to ignore the results, just don't run the test. What's the point of running a test if you're never going to follow up?
463.
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vikramkr
3y ago
But there's an added wrinkle of which language (either spoken or written) stays mutually intelligible with the current variant for the furthest amount of time back. And tons of languages exist that are Creoles and formed from pidgins a
464.
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vikramkr
3y ago
Dismissed by who? Dismissed by the media and public is one thing, but if you think investors are also dismissing them unfairly, that doesn't sound unfortunate at all. That sounds like an investment thesis.
465.
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vikramkr
3y ago
Idk if pinging like this works but @dang the title seems mangled on this one
466.
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vikramkr
3y ago
Think about how dramatic a change it was when computers started being able to efficiently add those numbers and got better than them. Now no matter what the human's capacity a huge number of them have a computer in their pocket that ca
467.
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vikramkr
3y ago
Worth it if it works equally as well in humans. We pay way more for cancer drugs that do way less.
468.
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vikramkr
3y ago
I guess there's nothing stopping people from just shamelessly making up data on Twitter even when they're linking the actual article. This is very cool and very promising research but "almost completely inhibits the growth of
469.
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vikramkr
3y ago
Well, of those 3 the 1998 internet bubble actually was different and modern society actually was fundamentally changed by the technology in question, so idk if that's the best counterargument. The other two, sure yeah those amounted to
470.
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vikramkr
3y ago
for social media though that's a pretty important end goal. If the people I want to follow aren't using it, then I don't want to use it either. It's like with messenger apps - the one that everyone else is using is the o
471.
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vikramkr
3y ago
The requirement is for POSTs in general, not just deletes. Anything that does actions outside of the system instead of just getting data
472.
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vikramkr
3y ago
That doesn't satisfy the requirement for a confirmation on each post request though
473.
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vikramkr
3y ago
They get nonprofit tax status and huge amounts of federal research funding. They're also a feeder for folks who end up in powerful leadership positions in society, and if they get the right to shape society, society also obviously rese
474.
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vikramkr
3y ago
That particular overconfidence in bashing Theranos as an outsider company who would never have been able to fool Real Silicon Valley (tm) is definitely a core part of the narrative that's developing, since nobody believes they'd h
475.
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vikramkr
3y ago
The term silicon valley has long since transcended geographic boundaries to signify the tech and vc/startup sectors as a whole. Facebook and Amazon and Uber and Theranos and FTX are all a part of it. It's about the culture and the
476.
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vikramkr
3y ago
Sure but we're in a string of silicon valley come to Jesus moments and finally having a case where the founder was so deluded they got even themselves killed is going to get airtime. I don't think there's be nearly as much in
477.
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vikramkr
3y ago
I like that there's an engine willing to break the spec. It's good to have variety and see how people experiment with this stuff, at least for the fun of it!
478.
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vikramkr
3y ago
Was the acquisition a win for the company that sold it or was it more of an aquihire deal? In the success case I think you could argue that was actually the ideal type approach for that company - focus on getting to the point where you or a
479.
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vikramkr
3y ago
I'm not saying ads are good. I'm saying the comparison to the past is stupid and it doesn't help the case against ads.
480.
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vikramkr
3y ago
The earlier 99 percent of human history was pretty garbage. Ads are pretty garbage too but I really don't get why people keep doing this thing where they're like "well how did we manage in the past?" In the past we just
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