tjohns

13 ms·

151.
by tjohns 2y ago
Yes, Lenacapavir is just a chemical. It's HIV itself that "knows" where the nucleus is and is actively trying to get there once it's inside your cell. It does this by walking itself along your cell's microtubial net
152.
by tjohns 2y ago
From Wikipedia: "Lenacapavir works by binding directly to the interface between HIV-1 viral capsid protein (p24) subunits in capsid hexamers, interfering with essential steps of viral replication, including capsid-mediated nuclear upta
153.
by tjohns 2y ago
It's because no other profession has the combination of (1) forcing people out of a highly trained role so young (with no options to reuse those skills in any other roles - forcing folks to go have to go back to square one and get a ne
154.
by tjohns 2y ago
The 30 year maximum age for hiring is there to make sure controllers have enough time working to earn pension benefits before mandatory retirement. Hiring someone older would be setting them up for a very bad time later in life.
155.
by tjohns 2y ago
Factor in the PR impact on the entire space program given the public visibility. We've never had an astronaut crew get stranded on the moon. though we got close with Apollo 13. If/when that happens for the first time, you'd b
156.
by tjohns 2y ago
You're paying for provably guaranteed reliability. When you're paying billions per rocket launch, you simply can't afford to have your robot break down on day 1 because of a software bug or because a component was accidently
157.
by tjohns 2y ago
For altitudes above 12,900 ft AGL, the official service volume for a DME is 100-130nm. Below that it's considered "line of sight"... and some quick math shows that you'd be able to get line of sight >50 nm for all alt
158.
by tjohns 2y ago
We already do something vaguely similar with MLAT, measuring the time delay from transponder signals at different receiver sites. MLAT data can be used for either unofficial situational awareness in non-radar facilities (to display non-ADS-
159.
by tjohns 2y ago
No. After about 5000 ft AGL (give or take) you can't pick up cell tower signals at all, since the antennas are directional and pointed towards the ground. This is a deliberate design decision, because even a low-altitude aircraft would
160.
by tjohns 2y ago
We pay attention to the Supreme Court (and Circuit Courts) in the US because those cases set legally binding precedent. Cases at both levels are well covered in the media with open access to dockets via PACER - and people should be paying
161.
by tjohns 2y ago
There's also a DME Minimum Operational Network, for airliners that can use DME-DME RNAV. (That's too expensive for smaller aircraft to install, though.)
162.
by tjohns 2y ago
NDBs/ADF are much more common outside the US, where there isn't a huge installed VOR network or where there is a need for long-range airways over remote terrain. (Canada, I'm looking at you.)
163.
by tjohns 2y ago
And just how are you delivering the key material for your one-time pad?
164.
by tjohns 2y ago
Don't try to play games with customs in the mail. It's a terrible idea. If you get caught, you and the person you're shipping to will both end up having your name flagged in the CBP database. You'll be scrutinized at the
165.
by tjohns 2y ago
> Software is too complex to be secure without a massive team IMO. We could do better as an industry though. Modern operating system design makes it far too easy to shoot yourself in the foot. Imagine a world where all we all use memory-
166.
by tjohns 2y ago
IC transit cards in Japan use heat-rewritable ink for something similar. The ticket vending machines print your monthly transit passes right onto the face of your card at the beginning of the month, and erase it after it expires. It's
167.
by tjohns 2y ago
Worst case, they could always use the other capsule that's docked to the ISS right now to get back. Though that would leave the current crew stranded up there until a replacement spacecraft can be sent. That takes several months. This
168.
by tjohns 2y ago
When you take the BasicMed class, you also have to report when your last physical was. Your physical date is public record is transmitted to the FAA and is part of your Airman Registry record. Yes, you could lie... but the documentation for
169.
by tjohns 2y ago
Insurance is primarily for major events. The things at the extreme upper end of the bell curve. For example, you've hit another car (possibly an expensive one) and caused tens of thousands of dollars in damage. Or you've inured a
170.
by tjohns 2y ago
You still need to get a physical (and sign off) from your primary doc every few years under BasicMed. Just not a full FAA flight physical. If someone has not had a documented physical at all in 8 years, they're not legal to fly. This i
171.
by tjohns 2y ago
A BFR is not just ground... you have to demonstrate airborne skills as well And even with BasicMed, your primary doctor has to certify that you are fit to fly. It's less rigorous than a full FAA flight medical by design, but it's
172.
by tjohns 2y ago
> They also were one of few automakers who wasn't selling your data to LexisNexis Risk Solutions for insurance pricing. I don't understand how this practice is legal. There really should be a way to request that my driving data
173.
by tjohns 2y ago
If your public library offers access to a repair manual database (many do), you can probably find it on there for free. I just checked and both Auto Repair Source and Chilton have manuals for that car in their database.
174.
by tjohns 2y ago
Many public libraries also offer access to a car repair manual database through their online collection. You need a library card, but the information is high quality.
175.
by tjohns 2y ago
At least in the US, the 911 infrastructure is dated. In older systems, your caller ID is sent using in-band DTMF tones, which are decoded by the dispatch computer. On newer E-911 systems they get some additional digital address data from th
176.
by tjohns 2y ago
It depends on the state. Some states allow winners to stay anonymous, others consider it a matter of public record. https://thehill.com/homenews/nexstar_media_wire/4531772-can-...
177.
by tjohns 2y ago
That's actively happening. 94UL was approved a couple years ago, and some of the smaller airports in the SF Bay Area are already dispensing it. 100UL was the last major barrier (since high performance aircraft need 100 Octane fuel), an
178.
by tjohns 2y ago
Most clients allow you to pick which font your plain text email is rendered in. Plain text gives the recipient control over how the content is rendered - as opposed to HTML which forces your choices on the reader.
179.
by tjohns 3y ago
Google Pixel phones will do this: https://guidebooks.google.com/pixel/optimize-your-life/use-d...
180.
by tjohns 3y ago
You don't strictly need training to use it, but training is still strongly recommended if you want to know how to use one effectively and have the best chance of survival. At a minimum, you need to know how to perform CPR in between

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