timy2shoes

14 ms·

91.
by timy2shoes 5y ago
What you call bugs I call features. See e.g. https://news.ycombinator.com/item?id=25443212
92.
by timy2shoes 5y ago
Yeah, they had one of the best remote talks I've ever seen at last year's NeurIPS: https://nips.cc/virtual/2020/public/invited_16166.html
93.
by timy2shoes 5y ago
It depends. Say in the case where you quit your current job, or move, or anything where you've spent or lost money based on a promise of a job, then you might be able to recover money on the basis on Promissory estoppel: https:/
94.
by timy2shoes 5y ago
The problem with defining clear goals for Quantum AI is that if you try to measure them then they will change.
95.
by timy2shoes 5y ago
The start of this line of thought was Robert Bork in 1978: https://en.wikipedia.org/wiki/The_Antitrust_Paradox
96.
by timy2shoes 6y ago
Yes, but that would require knowing how to rescue the phenotype, in this case healthy neurons and connections. Alzheimer's is not like Parkinson's, which you can (most likely, see the recent work from BlueRock) treat by replacing
97.
by timy2shoes 6y ago
With a limited NIH budget this will necessarily divert funds from other endeavors. In addition, I think such programs entrench the large lab bias prevalent in academia right now.
98.
by timy2shoes 6y ago
I think the overall goal assumes that genetics causes Alzheimer's, which is (in my opinion) a questionable assumption. That's not to say that the production of model systems for Alzheimer's will be useful, but will it be wort
99.
by timy2shoes 6y ago
Oversampling, then applying a train-test split? Jesus, that's like machine learning 101. But then again, I see a lot of questionable practices in the application of ML in biology.
100.
by timy2shoes 6y ago
Won't non-intact mRNA without a stop codon get degraded by Non-stop decay?
101.
by timy2shoes 6y ago
> Imaging based diagnosis could read presence or absence of particular gene mutations from the images so that the genes can be silenced by the drugs. >Imaging based diagnosis could also figure out whether a particular cancer precursor
102.
by timy2shoes 6y ago
Cas13 doesn't target DNA, rather targets RNA. It cuts the RNA, which then degraded. See https://www.sciencedirect.com/science/article/pii/S009286742...
103.
by timy2shoes 6y ago
Exactly. It's difficult to make causal claims from observational data, and made worse by the constant flood of causal claims coming out of microbiome labs. At best there's anecdotal evidence, at worst researchers are peddling sn
104.
by timy2shoes 6y ago
Converting text to numbers via individual characters destroys any semantic meaning to the input. Which is why no advanced NLP tools will do such a thing. Basically, what they describe takes whatever meaning is in the title and throws it in
105.
by timy2shoes 6y ago
Title A: Show HN: New grep tool written in Python Title B: Show HN: New grep tool written in Garbage (1% better) I guess Python is 1% worse than garbage. Lol
106.
by timy2shoes 6y ago
Yeah, this is a classic case GIGO. > Title A: kdjfs;dfisd;diofuosd > Title B: sdlkn nmkd kljdsa;'[ (10% better) > The winner is title B: sdlkn nmkd kljdsa;'[
107.
by timy2shoes 6y ago
There's so much more missing that makes me think this is an engineer writing about how biological research should be in theory, without the understanding and experience the complicated nature of biological research. Well, suppose we w
108.
by timy2shoes 6y ago
We can't have large investors losing money on any of their (inherently risky) investments. How will the market work if investors can lose money?
109.
by timy2shoes 6y ago
Yes, and it's difficult to get information from charter schools because they are not subject to the same reporting that public schools are. This makes it easy for people take advantage of their opaqueness. These are a few examples fro
110.
by timy2shoes 6y ago
You can open it in incognito mode to avoid the paywall.
111.
by timy2shoes 6y ago
If y = 2^x, then log y != 2^log x because of Jensen's inequality. You can take log of both sides to keep the equality, but applying the transformation inside of 2^() results in the equality turning into a strict inequality.
112.
by timy2shoes 6y ago
Exactly. Biases in previous data will be amplified with predictive policing algorithms. See, for example, https://rss.onlinelibrary.wiley.com/doi/full/10.1111/j.1740-...
113.
by timy2shoes 6y ago
Seems pretty straight forward. 162,000 kcal / 239 kcal = 677.8
114.
by timy2shoes 6y ago
Please read https://sfconservancy.org/copyleft-compliance/principles.htm... . My understanding is that if you do not enforce your copyright (or copyleft in this case) you can lose the copyright.
115.
by timy2shoes 7y ago
DNA is made of nucleic acids (deoxyribonucleic acids), not amino acids. DNA is translated to amino acids, except when it encodes long-noncoding RNAs, or miRNAs, or piRNAs, or untranslated regions, or intergenic regions, or transposons, or