thenerdhead

11 ms·

91.
by thenerdhead 2y ago
Yep they do. Provenance and especially "build provenance" are what they are referring to but definitely misspell it. https://slsa.dev/spec/v0.1/provenance
92.
by thenerdhead 2y ago
I like how they encourage best practices using a score similar to pub.dev & what npm tried to do years ago. Also the compatibility portion is quite interesting given the evolution of runtimes. I suppose I don't quite understand the
93.
by thenerdhead 2y ago
There is rationale in the science article I posted above. The current hypothesis is viral reservoirs that are replication competent. Here is the blurb as well: > Paxlovid targets virus that is rapidly replicating—which may or may not be
94.
by thenerdhead 2y ago
Not true. There has been evidence of long term symptoms months after the first wave in 2020. By 2021 established hypotheses of viral persistence existed. Viral persistence(2021): https://www.frontiersin.org/journals/mic
95.
by thenerdhead 2y ago
I grew up in Utah which has a certain religious culture mixed in entrepreneurship. Very good salespeople but not always morally right depending on your beliefs. The broadway show “The Book of Mormon” is a good satire as to what I’m talking
96.
by thenerdhead 2y ago
People have and have been successful. Especially repurposing HIV/AIDS drugs and ordering Paxlovid from India. Mostly due to USA prices being ridiculously high and insurance companies refusing to prescribe more than a 5 day dose. The ot
97.
by thenerdhead 2y ago
In 2021 I presented my doctor a hypothesis that a COVID infection I had recently was persisting in my body leading to long term symptoms. They told me I was completely wrong and that RNA viruses do not do that. Fast forward to today and the
98.
by thenerdhead 2y ago
Dang I knew this guy from the Utah startup scene and always got weird vibes. Doesn’t surprise me one bit.
99.
Covid-19 Virus Can Persist in the Body More Than a Year After Infection(polybio.org)
3 points by thenerdhead 3y ago|0 comments
100.
by thenerdhead 3y ago
Ugh, so sorry to hear that. I'm an email away if you ever want to chat about it.
101.
by thenerdhead 3y ago
Long COVID is horrible. I have had it for three years. I follow the research quite closely and wrote a book about what we know about it, how it affects someone and their health, and some observations on how absurd of a condition it is from
102.
by thenerdhead 3y ago
This might be interesting to you: https://www.acpjournals.org/doi/10.7326/M23-1831 It is suggested that many viruses can do this.
103.
by thenerdhead 3y ago
There are pathogens that have! https://www.cell.com/cell/fulltext/S0092-8674(23)01034-6
104.
by thenerdhead 3y ago
Yes I think this pattern will get much clearer in the near future. We already see these links with chronic illness, depression, etc and gut dysbiosis. One thing I wouldn’t count out is the effect of lingering virus or viral antigens causing
105.
by thenerdhead 3y ago
What excites me the most is if we are successful with projects like https://www.humanimmunomeproject.org/ and to map our findings to the prior Human Microbiome project - https://www.hmpdacc.org/overview&#x2F
106.
by thenerdhead 3y ago
Either you care enough to read my comment and link to comment back or you don’t. That’s called decency. Not my laziness to be quite honest with you. There’s now two comments and yet you still haven’t cared to respond about the original comm
107.
by thenerdhead 3y ago
Ah sorry I assumed people read comments. Here is a summary https://youtu.be/HgcRCKdf9qg?si=7F0saD9UDEMkgFn9
108.
by thenerdhead 3y ago
Ah so a patent company who wanted to make a profit? https://www.regulations.gov/docket/FDA-2023-E-2605 Interesting!
109.
by thenerdhead 3y ago
You clearly didn’t read or understand what the bill is saying. This might be helpful to understand context too: https://youtu.be/ma0xH0EI7Us?si=Qhg5pz6-FgYC0j_o
110.
by thenerdhead 3y ago
Yes they are free to do that if their drugs work. That’s allowed in any capitalist market.
111.
by thenerdhead 3y ago
You don’t seem to understand the bill and perhaps people are downvoting because they don’t understand either. I recommend you read it yourself and understand what it is saying. Not to make broad assumptions that “snake oil” will be allowed.
112.
by thenerdhead 3y ago
Not true. You can mark certain confirmed illnesses with provisions. Quacks won’t be allowed in such regulated environments. https://www.congress.gov/bill/118th-congress/senate-bill/190...
113.
by thenerdhead 3y ago
The FDA is not that slow though. People misinterpret that it is actually the trials that are slow. Many things get approved quickly for as large of an enterprise as the FDA.
114.
by thenerdhead 3y ago
As it should. That’s the risk they take. Either you have a well designed trial that shows your drug is effective or you don’t. What you don’t do is make lofty promises to vulnerable patients.
115.
by thenerdhead 3y ago
What work does the FDA do here? It is the work of large investments or initiatives to prove safety and efficacy and the FDA makes decisions. If anything we live in a world where we need better provisions for these illnesses similar to http
116.
by thenerdhead 3y ago
https://www.congress.gov/bill/118th-congress/senate-bill/190...
117.
by thenerdhead 3y ago
How about we fix that with this? https://www.congress.gov/bill/118th-congress/senate-bill/190... Give patients access and do the right science. Make sure it is safe and allow people the right to try.
118.
Systems analysis of innate and adaptive immunity in Long Covid(sciencedirect.com)
1 points by thenerdhead 3y ago|0 comments
119.
Targeting G9a to develop Covid-19 and Long Covid treatments(biorxiv.org)
2 points by thenerdhead 3y ago|1 comments
120.
by thenerdhead 3y ago
Inhibiting the G9a protein could help stop the COVID-19 virus from hijacking our cells to replicate, offering a new way to treat COVID-19. For Long COVID, targeting G9a might also help alleviate lingering symptoms by potentially reversing t

More ›