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t_serpico
searching PlanetScale…
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7 ms
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31.
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by
t_serpico
4y ago
There is a fundamental difference between the two examples. There are strong social pressures to join social media. Opting out of social media could lead to a less rich social life, especially for younger people. Thus, there is perceivably
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t_serpico
4y ago
Only way to truly learn biology imo is to read and do experiments. The feedback loop between those two things is what actually gives someone real intuition.
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t_serpico
4y ago
Well put. I ultimately view observational studies as hypothesis generators that can spur research into more targeted questions all the way down to the biochemical level.
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t_serpico
4y ago
On average yes, but I tend to agree that the 'jock' tech worker is an archetype that didn't exist 20 years ago. Tech is no longer counterculture and has become a more high status profession in the eyes of the public. This is
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t_serpico
5y ago
lol
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t_serpico
5y ago
cute story, welcome to the world of healthcare.
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by
t_serpico
5y ago
Unifying clinical and biological data is an incredibly challenging task for a variety of reasons. Private sector is much more well suited to tackle such problems because of the engineering and coordination required.
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t_serpico
5y ago
I think renaming was a massive strategic mistake. The metaverse, even if it succeeds from a technical standpoint, will need to be deemed 'cool' for people to adopt it. And generally, if you have something cool, you don't prem
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Water’s Hydrogen Bond Strength
(arxiv.org)
1 points
by
t_serpico
5y ago
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0 comments
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t_serpico
5y ago
To avoid waiting for consensus, how about we decide to each send a random color and in the next turn announce the color that is first alphanumerically? We each know our own color and the color our partner sent.
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t_serpico
5y ago
The “protein folding problem” consists of three closely related puzzles: (a) What is the folding code? (b) What is the folding mechanism? (c) Can we predict the native structure of a protein from its amino acid sequence? ( https://
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by
t_serpico
5y ago
You pick up relatively quickly fingerings that work. It's a matter of intuition and pattern matching.
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t_serpico
5y ago
Great point. They're primed for this.
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t_serpico
5y ago
"I feel like these kinds of papers only exist to be cited in support of cheap rhetoric." Agreed. The authors already made up their mind regarding the conclusion before writing the paper. This is an analysis that should be done by
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t_serpico
5y ago
To me, the interesting thing is not the specific results but rather that you can accurately predict crystal structures from sequence alone. This begets the question: what other physical biological properties can we predict?
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t_serpico
5y ago
I wouldn't really consider this company a 'moonshot', unless you want to label all drug discovery company moonshots.
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t_serpico
6y ago
True, and the exact same thing can be said about classical music. The average person needs some sort of framework to learn the art form. And yes, this is more imitation than innovation, but nevertheless can serve as a framework for musical
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t_serpico
6y ago
nice. glad to see this exists.
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by
t_serpico
6y ago
The question is why would you gossip on CH? My guess is that there is some excitement to 'getting caught' or just more generally doing it in public. It's like the equivalent of having a private conversation in a bar or coffee
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t_serpico
6y ago
It would probably be safer for him to actually get covid than develop your own diy vaccine...
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t_serpico
6y ago
"The professional...must fight to preserve the naiveté that the layman already possesses" - a genius quote by Bill Evans that applies to more than just music.
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t_serpico
6y ago
Garbage is a strong word. I think there's definitely a moderate to strong correlation between h-index and quality of researcher. The downside with the h-index is that it also measures your ability to play the 'game' (i.e netw
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t_serpico
6y ago
well said
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t_serpico
6y ago
ggplot >> matplotlib and dplyr >> pandas. its not even close imo.
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by
t_serpico
6y ago
Out of curiosity, why not?
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by
t_serpico
6y ago
Also, one important thing to realize is that AlphaFold was trained largely on proteins that we were able to crystallize. I'd be very curious to see how its performance fares as a function of 'ease of crystallization'.
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t_serpico
6y ago
Also, pharma does not really have a huge incentive to work on this problem. Solving the protein folding problem does not automatically translate to new drugs just in the same way CRISPR or DNA sequencing did not. It's another tool in t
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t_serpico
6y ago
You hit the nail on the head here.
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t_serpico
6y ago
This is true. If I wanted to have independent thoughts for things I believe basically because most people believe them, I would not have the time to do anything else. Some people have this drive and capacity but most don't.
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t_serpico
6y ago
That is fascinating. Could you point me towards some of his policies that benefit minorities? Genuinely interested. I'm also in agreement with you that most people who vote for Trump do so in spite of his character, not because of it.
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