strbean

5 ms·

31.
by strbean 2mo ago
I read it as "After finishing the course, I DM'd the hiring manager with a list of the stuff I did for the course."
32.
by strbean 2mo ago
> When rapid progress is made in a poorly-understood field, then how can our definitions and requirements for success not change? It's in how they change, not the fact that they change. The skeptics seem to have secret definitions f
33.
by strbean 2mo ago
Can I ask what your MUD is called?
34.
by strbean 2mo ago
> I would take a small dose at like 7am, and I still would have trouble getting to sleep at night Was this an extended release verson like Vyvanse? I had an absolutely terrible time with that for the same reasons. If that was your experi
35.
by strbean 2mo ago
> Why do you expect pseudoephedrine to be less nasty on the cardiovascular system than caffeine? I'm not advocating for substituting pseudoephedrine for caffeine, but rather using pseudoephedrine as a one time proxy for amphetamine
36.
by strbean 2mo ago
And a hypothetical banning that isn't totally unreasonable if you look at it objectively. What other highly addictive cardiotoxic stimulants should we allow to be sold over-the-counter with no age limits whatsoever?
37.
by strbean 2mo ago
Consuming that much caffeine is terrible for your heart. If you find yourself consuming a lot of caffeine regularly, you would probably be much better served by Adderall. You can get the same stimulant effect with much less wear and tear on
38.
by strbean 3mo ago
> even what can be done. I think this could be solved with bridge bots to make your MUD multiplatform. You could have a dedicated web app, an IRC bridge, a Discord bridge, etc. Discord-brained users can still use your MUD and contribute
39.
by strbean 3mo ago
Routing tasks to models by complexity like a job for a LLM. I'm sure there are degenerate cases, but I'd bet a relatively small model could do the job.
40.
by strbean 3mo ago
That's actually an important part of the theory of Roko's Basilisk. The danger of being tortured only applies to those who are aware of it. Supposedly, the incentive to torture you only exists if you were aware of the implied thre
41.
by strbean 3mo ago
> Once you're around 80 it'll wake up anyone Source? I haven't been able to find info on this. I get resuls on nocturnal tachycardia and such. Nothing on elevating a sleeping person's heart rate and observing the resu
42.
by strbean 3mo ago
With respect to this idea, I'm not particularly interested in either of those goals. More the general longevity and health improvements that come with regular exercise irrespective of weight loss or muscle gain [1]. I haven't been
43.
by strbean 3mo ago
Well, it's causing muscle contractions. At high enough intensity, it should raise your heart rate. It's just a matter of what intensity level is tolerable during sleep (and the effect on sleep quality), no?
44.
by strbean 3mo ago
I'd love to find out if electrical muscle stimulation while sleeping could effectively provide exercise without causing excessive sleep disruption. Could be a zero-effort supplemental form of exercise for sedentary people.
45.
by strbean 4mo ago
Interesting, I've got a Sony Google TV and it's been the best smart TV experience I've had in a long time. Prior to that was Samsung TVs and a Roku TV (forget which manufacturer) and they all had massive decay in performance
46.
by strbean 4mo ago
Interesting, thanks for the info! Another question: how does this approach compare to trying to repair the pathogenic variants in the cancer? I asked here about that approach recently and the response was mainly about delivery difficulties:
47.
by strbean 4mo ago
> Indeed, there's no "be a better/stronger cancer and spread more effectively to more hosts" the way there is with bacteria or a virus. The rare exception: https://en.wikipedia.org/wiki/Clonally_t
48.
by strbean 4mo ago
Depending on how the LNPs are designed, would resistance also potentially cripple the cancer cells? Like, it stops surfacing some cholesterol receptor because the drug is being delivered by LNPs that target that receptor, and now the cell i
49.
by strbean 4mo ago
_RelationshipBackPopulatesArgument = Union[ str, PropComparator[Any], Callable[[], Union[str, PropComparator[Any]]], ]
50.
by strbean 4mo ago
Seems like that's... one more substantive meeting? First link is announcing the initiative was submitted, second is a private meeting where the initiative was presented to the comission by the organizers. Then there was a public meetin
51.
by strbean 4mo ago
If a game is popular enough for anyone to care, some turbonerd will get the server running on a massive cloud instance, and then people will be able to play the game. Fans have reverse-engineered and stood up servers for tons of games with
52.
by strbean 4mo ago
> but not the EU which is currently being drafted (in a different direction) Where can we find information about the direction the EU is going on this? AFAICT there has just been one meeting on the topic?
53.
by strbean 4mo ago
Imagine if every tweet had to go through a one-at-a-time queue before being persisted. There's about 6000 tweets per second, so you would have to be able to save them at <0.17ms per tweet or else you would become backlogged. If you
54.
by strbean 4mo ago
So for masses of solid tissue, we can't effectively deliver the payload to all the cells? How about for lymphomas?
55.
by strbean 4mo ago
> You'll note that even Java now recognises that "public static void main(String[] args)" was pointless ceremony. There is still the part of the ceremony that actually mattered: having a single entrypoint instead of the op
56.
by strbean 4mo ago
What's the status of just using CRISPR to fix pathogenic variants?
57.
by strbean 5mo ago
Plug for my buddy's project: http://agentsh.org/ Block agents from misbehaving at the OS level instead of asking them to behave.
58.
by strbean 5mo ago
See also https://en.wikipedia.org/wiki/Double-stranded_RNA_activated_... This one is quite tinfoil-hat inspiring, as the research was moved to defense-focused Draper Labs and then immediately disappeared.
59.
by strbean 5mo ago
I know a an accomplished CS professor, ACM fellow, cited in Knuth's TAOCP (as well as being an easter egg!), who still hunt-and-pecks. In fact, hunt-an-pecks incredibly slowly . Seeing him type really reinforced this idea.
60.
by strbean 5mo ago
A lot of really good reasons: 1) Higher level code is easier for LLMs to review and iterate upon. The more the intent is clear from the code, the easier it is for humans and LLMs to work with. 2) LLMs get stuck or fail to solve a problem

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