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stevenjgarner
searching PlanetScale…
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5 ms
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31.
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stevenjgarner
8mo ago
The researchers identified the DMTF1 protein as a key regulator that declines with age, and they successfully restored neural stem cell renewal by reactivating its specific genetic pathways in both human-derived cells and mouse models. How
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Protein Discovered That Reverses Brain Aging in the Lab
(science.org)
1 points
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stevenjgarner
8mo ago
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1 comments
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stevenjgarner
8mo ago
I think that may be an insight to something quite profound. We used to measure the "doubling of knowledge" against number of peer-reviewed papers of scientific research etc. Now not so much. "Knowledge" has become mor
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stevenjgarner
8mo ago
I agree the administration tariffs "wouldn't be levied on manufacturing inputs" if they really wanted to help domestic industries. I'm not saying they're doing the right thing, I'm just saying that most Americ
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stevenjgarner
8mo ago
Most people here in the US that I talk to understand that the additional tariffs imposed by the Trump administration are an attempt to get domestic US industries to produce the items that are now being imported subject to the tariff. In so
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stevenjgarner
8mo ago
https://www.google.com/maps/place/Taklamakan+Desert/@38.8709...
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stevenjgarner
8mo ago
While Walmart has historically denied using "individualized" pricing (charging two people different prices for the exact same item based on their income), they do use behavioral targeting [1] Members of Walmart+ often see differen
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stevenjgarner
8mo ago
Why is knowledge doubling no longer used as a metric to converge on the limit of the singularity? If we go back to Buckminster Fuller identifying the the "Knowledge Doubling Curve", by observing that until 1900, human knowledge d
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stevenjgarner
8mo ago
$3.88 ? Walmart.com uses dynamically variable pricing that includes geographic and user variance - my price is $5.92 https://www.walmart.com/ip/Mainstays-Basic-Indoor-8-78-Black...
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stevenjgarner
8mo ago
This makes a lot of sense. The commercial launch business is not large enough to support all possible Falcon launches, so Starlink was created to take advantage of the low launch cost and vertical integration and is now a major profit cent
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stevenjgarner
8mo ago
Elon Musk’s AI startup, xAI (x.ai = grok), officially acquired X Corp. (the parent company of the social media platform X or x.com, formerly Twitter/x.com) in an all-stock deal. Both now operate under a unified holding entity, frequen
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Magnetic core memory 128-byte USB drive
(tomshardware.com)
11 points
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stevenjgarner
8mo ago
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1 comments
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stevenjgarner
8mo ago
It is often argued that the US will grow its economy such that the debt is less significant. There is much confusion between the US debt being cited as a ratio of GDP (common among economists) vs net tangible assets (common among businesse
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stevenjgarner
9mo ago
Agreed. However, the 2020 Census had a reported "net coverage error" of only about -0.24%, which I seriously question in the case of SD.
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stevenjgarner
9mo ago
Even in the USA, the census is not as accurate as it thinks (without even getting into the homeless situation). South Dakota is the capital of the "Nomad" phenomenon because of its favorable residency and tax laws for full-time t
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stevenjgarner
9mo ago
> Here’s my favorite fact: Papua New Guinea, with about 0.1 percent of the world’s population, hosts more than 10 percent of the world’s languages. Two villages, separated perhaps only by a few miles, will speak languages that are not mu
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stevenjgarner
9mo ago
Yes current EVs are heavy. It's not at all clear that this will prevail as solid state batteries evolve to become standard. It is highly possible that EVs will soon be lighter than comparable ICE vehicles [1] [1] https://n
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stevenjgarner
9mo ago
The assertion that 'I just hope "dumb" EV's become a thing soon' led me to a different assumption. The ultimate aspiration of a "smart" EV is self-driving, which incorporates Internet connectivity feature
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stevenjgarner
9mo ago
That is not the argument being made. We are discussing how "dumb" vehicles (e.g. vehicles that contribute to 50,000+ fatalities annually) provide independence, privacy and freedom that "smart" vehicles (e.g. vehicles wi
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stevenjgarner
9mo ago
So liberty then. I don't disagree with you, but this modern flashpoint in the classic debate between individual liberty and collective safety does bring up the question what is saving 50,000+ lives annually actually worth in terms of
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stevenjgarner
9mo ago
Why? Are you worried from a liberty/privacy standpoint? "Smart" EV's are demonstrated to be significantly safer than "dumb" EVs. Waymo’s 2025/2026 data shows an 80–90% reduction in injury-causing crashe
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stevenjgarner
9mo ago
It wasn't an absence of a market. Those of us that had to manage OSX Server soon found out the software was marked by several high-profile bugs, technical debt, and a perceived decline in reliability. I migrated a large number of Mac
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stevenjgarner
9mo ago
Alternative to paywall: https://archive.ph/8xF1w
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stevenjgarner
9mo ago
Michael Levin’s research fundamentally challenges the traditional biological view that intelligence is exclusive to the brain, proposing instead that "mind" and agency are distributed throughout all levels of biological organizati
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stevenjgarner
9mo ago
Long-duration spaceflight causes a significant physical shift of the human brain within the skull, moving it backward, upward, and rotating it in pitch. By analyzing MRI scans of 26 astronauts, researchers found that these displacements—rea
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stevenjgarner
9mo ago
This study reveals that 18 of Earth’s largest river deltas, including the Nile and Amazon, are sinking at rates significantly faster than global sea levels are rising, driven primarily by localized human activities like groundwater extracti
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Global Subsidence of River Deltas
(nature.com)
2 points
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stevenjgarner
9mo ago
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1 comments
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Brain displacement and nonlinear deformation following human spaceflight
(pnas.org)
3 points
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stevenjgarner
9mo ago
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1 comments
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We Were Wrong About Our Minds–and AI
(youtube.com)
1 points
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stevenjgarner
9mo ago
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1 comments
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stevenjgarner
9mo ago
I wonder how much the 2026 SNAP food stamp item rule changes will move this needle further, with several states using new federal waivers to restrict "junk food" items like soda, candy, energy drinks, or prepared desserts?
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