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stenl
searching PlanetScale…
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13 ms
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31.
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stenl
4y ago
DNA: https://en.m.wikipedia.org/wiki/DNA_digital_data_storage It will last 10k years if stored reasonably. Storing GBs is no problem. Won’t go obsolete - the technology has been around for nearly four billion years.
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stenl
5y ago
Or maybe we need the opposite: basically just state that you did this stupid stuff only to avoid the tax, so you should pay the tax anyway.
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stenl
5y ago
Assuming you have found a drug that is safe and binds the target in the intended way (which itself can take years), you then have to manufacture it according to GMP standards. That takes at least a year and $1 million. Next, you have to run
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stenl
5y ago
Leipzig has a nice zoo, and it’s one of the rare zoos that has Bonobos. They are amazing to watch: mothers happily walking upright holding their baby, lots of playing, just generally enjoying themselves. To me they seem much more human than
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stenl
5y ago
The single-letter variable names and the lack of types (beyond some duck-typing using bold and uppercase) is what makes math so difficult to read (for me). There must be tons of errors in math papers that go undetected just because there’s
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stenl
5y ago
Hey vanderZwan, we have a paper in the collection (there’s 17 brain atlas papers in this issue of Nature) on human, marmoset and mouse motor cortex (my group did the human). I think it’s cool that pretty much all the cell types could be ali
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stenl
5y ago
The size of the tumor likely makes a big difference too: a centimeter-sized lump contains 1000x more cells than a millimeter-sized one. It will contain 1000x more drug-resistant cells (given identical mutation rates). For example, a human b
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stenl
5y ago
It’s just a protein, so it’s not very expensive to make. I guess a few hundred dollars? Here’s one seller: https://listlabs.com/products/bacterial-toxins/?sub=botulinu...
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stenl
5y ago
I once bought some pure botulinum toxin for an experiment (it blocks the release of acetyl choline at neuromuscular junctions). I want to say it was a milligram, but I don’t remember (that would have been 1000 times the lethal dose by inhal
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stenl
5y ago
In first grade we were given a workbook for learning how to write the letters. There was one whole page of A, one page of B, etc. You had to write maybe 100 As in a row. The kids quickly figured out that the fastest way to do it was to firs
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stenl
5y ago
Cool. Ulrika’s office is across from mine, and this is a more extensive follow-up of work we did together in 2018 to map neuron types in the gut (and in the whole nervous system). I’m pretty sure Ulrika wouldn’t claim to know how the ENS wo
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stenl
5y ago
Video is here, and a link to the paper: https://twitter.com/SciRobotics/status/1395413569571786752
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stenl
6y ago
There’s massive innovation in biotech right now. RNA vaccines are winning the COVID battle, based on extremely cool technology (pseudouridine to evade innate immunity, two prolines to lock the spike in prefusion conformation, lipid nanovesi
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stenl
6y ago
I once departed Stockholm on Jan 1st, flying to San Francisco. The route goes north, across the polar circle and over Greenland, then south towards the US west coast. As we passed the polar circle, the sun set. A few hours later, we passed
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stenl
7y ago
There is lag in the reporting I think. The total number of patients increased by 39 from yesterday, but those were probably assigned to multiple dates in the past. Therefore it will always look like the last few days are declining.
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stenl
7y ago
James Watson - who was as close to royalty as you can get in science - worked very long and hard to get himself fired. It wasn’t just ”an interview”, but a lifetime of racism and sexism. Lior Pachter has a handy collection of quotes with li
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stenl
7y ago
More importantly, the specific and incredibly successful class of immune checkpoint inhibitors(PD-1 inhibition is one example) got the Nobel Prize in medicine 2018, awarded to Tasuko Honjo and James Allison. See https://www.nobel
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stenl
7y ago
Seems like only a small win for such a large key. I type a lot of math and have been happy mapping Caps Lock to ”Change keyboard layout to Greek” (macOS). It gives me quick and effortless access to the full greek alphabet.
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stenl
7y ago
Obama pursued policies that arguably ( https://www.amnestyusa.org/the-obama-bush-doctrine/ ) amount to war crimes, and refused to allow the obvious war crimes of the preceding administration to be investigated. He got a
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stenl
7y ago
For those who didn't get the reference, "Bowling alone" refers to an influential 1995 essay and a book by Robert Putnam about the decline of social capital in the United States since 1950: https://en.wikipedia.org&
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stenl
7y ago
The title of the post is wrong though. He’s talking about migrating outside the solar system (i.e. to exoplanets), not just to other planets (e.g. Mars).
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stenl
7y ago
Everybody (90% of over-12s) has a smartphone but you can also use a computer. 98% have internet at home. Edit: latest statistics show >95% have BankId on a smartphone. See https://www.bankid.com/assets/bankid/st
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stenl
7y ago
Sigma Aldrich sells a kilo of pure bromoform for about $300. I’m sure bulk bromoform is much cheaper.
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stenl
7y ago
In Sweden, the password is BankId, a two-factor authentication app that everybody has on their phones. It’s used by all government agencies, banks and insurance companies etc to establish identity. You literally use your ssn as username to
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stenl
7y ago
International law definitely exists. In fact, Wikipedia has a whole long and interesting article about it: https://en.m.wikipedia.org/wiki/International_law Another example: international law bans torture, enforceable
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stenl
7y ago
For example, the Iraq war was not approved by the UN Security Council, which is the only forum that can approve the use of force between (UN member) countries, apart from self defence. See https://en.m.wikipedia.org/wiki
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stenl
7y ago
Related Science paper from last summer ”All-Optical Machine Learning Using Diffractive Deep Neural Networks” https://arxiv.org/pdf/1804.08711.pdf and https://science.sciencemag.org/content/361/
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stenl
7y ago
$1300/month is absolutely crazy. In Sweden, a whole year’s worth of injection insulin is about $600 (actual cost to the government, including the disposable injectors) and $0 to the end user.
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stenl
7y ago
Why do they claim that Word ditched its equation editor? I believe I’m on the latest Word and it certainly still has the editor. Word’s equation editor is hands-down the best WYSIWYG equation editor I ever used. The results are beautiful an
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stenl
7y ago
InDesign is great, but how do you typeset equations in it? Genuine question, as I’ve searched far and wide for a viable solution. The best I have so far is ”create in another software and insert as an image”, which is unsatisfactory.
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