skmurphy

14 ms·

1. 241.▲
   Treat Your Spouse as an Investor(skmurphy.com)

   2 points by skmurphy 3y ago|3 comments
2. 242.▲
   by skmurphy 3y ago

   Karri Saarinen tweeted this today (Jan 6) at 8:36am https://twitter.com/karrisaarinen/status/1743672776643535015 he provides a helpful perspective on why Carta might be tempted to leverage customer information to
3. 243.▲
   by skmurphy 3y ago

   I think you are on to something with a checklist for benchmarking how solid a research claim is: Where was it conducted: in silico (simulation only) in vitro (test tube only) in mice (or other animal study) how old is it: w
4. 244.▲
   by skmurphy 3y ago

   We offer online events for bootstrappers including Bootstrappers Breakfast and Lean Culture. There are also in-person Bootstrapper Breakfast meetings in Ft. Worth, Las Vegas, San Francisco, and Silicon Valley. These events are for “entrepre
5. 245.▲
   Roundup of January 2024 Bootstrapper Events(bootstrappersbreakfast.com)

   1 points by skmurphy 3y ago|1 comments
6. 246.▲
   by skmurphy 3y ago

   CONCLUSION "Conclusion: Our results support the idea that more-diverse microbiomes can provide health benefits, specifically that they can improve protection against pathogen colonization. We also find that colonization resistance is a
7. 247.▲
   Microbiome diversity protects against pathogens by nutrient blocking(science.org)

   1 points by skmurphy 3y ago|1 comments
8. 248.▲
   by skmurphy 3y ago

   I was an early user of Verilog at MMI/AMD in 1985-88 and attended the first Verilog user group. The article only mentions TEGAS once, but it was a widely used incumbent and the gate-level descriptions in Verilog matched the TEGAS synta
9. 249.▲
   by skmurphy 3y ago

   Summary: The transparency of ocular media offers a unique opportunity for direct visualisation of the microvascular circulation, and recent advances in optical coherence tomography (OCT) have enabled high-resolution identification of specif
10. 250.▲
    Oct Based Eye Scans Offer Non-Invasive Monitoring of Kidney Disease(medscape.co.uk)

    1 points by skmurphy 3y ago|1 comments
11. 251.▲
    by skmurphy 3y ago

    We offer online events for bootstrappers including Bootstrappers Breakfast and Lean Culture. There are also in-person Bootstrapper Breakfast meetings in Ft. Worth, Las Vegas, San Francisco, and Silicon Valley. These events are for “entrepre
12. 252.▲
    Roundup of Events for Bootstrappers in December 2023(bootstrappersbreakfast.com)

    1 points by skmurphy 3y ago|1 comments
13. 253.▲
    by skmurphy 3y ago

    Thanks I did not realize this. My excerpts are from the original version, most of them no longer appear in the text.
14. 254.▲
    by skmurphy 3y ago

    I posted these excerpts about an hour after the original post went it. The article has now been substantially re-written (with no indication in the text of the changes) and most of the sentences I excerpted have been removed. It was an accu
15. 255.▲
    by skmurphy 3y ago

    Thoughtful analysis of dynamics in play at OpenAI that may have led to his firing and likely will result in his reinstatement. Key take-aways (excerpts from article): "The board made a blunder. OpenAI’s employees will likely get their
16. 256.▲
    OpenAI Boardroom Battle: Safety First(fabricatedknowledge.com)

    45 points by skmurphy 3y ago|42 comments
17. 257.▲
    by skmurphy 3y ago

    We offer online events for bootstrappers including Bootstrappers Breakfast and Lean Culture. There are also in-person Bootstrapper Breakfast meetings in Ft. Worth, Las Vegas, San Francisco, and Silicon Valley. These events are for “entrepre
18. 258.▲
    Roundup of Events for Bootstrappers in November 2023(bootstrappersbreakfast.com)

    2 points by skmurphy 3y ago|1 comments
19. 259.▲
    by skmurphy 3y ago

    Not true if it's not protectable (patentable). Real world testing--e.g. clinical trials--is very expensive and when others can immediately benefit the results pharma unlikely to pursue.
20. 260.▲
    by skmurphy 3y ago

    "Human connection does not scale" is succinctly expressed insight. You identify the follow on implications and what can be done to preserve it. Thank you.
21. 261.▲
    by skmurphy 3y ago

    The times are urgent; let us slow down." This is good advice. Faster skims the surface, slowing down allows you to work more smoothly and at a deeper level. You see it reflected in other aphorisms: "Slow is smooth and smooth is fa
22. 262.▲
    by skmurphy 3y ago

    Full sentence: "Johnson, who said that he was also an informant for Buma, told Insider that he believes that Thiel's reporting to the FBI was largely limited to foreign contacts and attempts by foreign governments to penetrate Sil
23. 263.▲
    by skmurphy 3y ago

    Guidelines for Show HN at https://news.ycombinator.com/showhn.html are pretty clear that most of what is suggested in the tweet thread is out of bounds
24. 264.▲
    by skmurphy 3y ago

    The problem is that writing code, in an of itself, does not create value. Because you did not start with a clear customer need you are suffering from the "sunk cost fallacy" that the work you have done is worth something. Many peo
25. 265.▲
    by skmurphy 3y ago

    “Most people want certainty. They want to feel comfortable. And then the true founders, they want to find chaos, and they want to turn chaos into order.” Garry Tan I thought this quote summarized an important insight for founders. It echoes
26. 266.▲
    by skmurphy 3y ago

    Do you disagree with any of the six points I posted from the book?
27. 267.▲
    by skmurphy 3y ago

    There were several good suggestions clearly expressed, but I agree the signal-to-noise ratio was not great--also true for a lot of books and articles you can still learn from. What would you recommend as better books or articles on the topi
28. 268.▲
    by skmurphy 3y ago

    We measure trust all the time: everyone you work with keeps track of whether you tell them the truth and meet the commitments that you make. People also assess your productivity and the quality of your results in deciding whether to work wi
29. 269.▲
    by skmurphy 3y ago

    I think the designation of a facilitator and the guideline for one conversation around the table makes a significant difference and lets everyone become better acquainted. Priya Parker's "Art of Gathering" ( https:/&#x2F
30. 270.▲
    by skmurphy 3y ago

    Lynch's syndrome is not a general term but a specific inheritable genetic mutation that affects about 1 in 270. It puts them at higher risk for certain kinds of cancer. The reason to get tested, if you have one or more relatives who ha