samuell

6 ms·

61.
by samuell 5mo ago
I shared this since it seems to address a somewhat similar niche that I have had hopes to one day develop, based on FlowBase [1]; A library of streaming processing components based on basic operations, that can be easily stitched together i
62.
by samuell 5mo ago
Yeah, there is actually a pretty big shift towards Rust in the comp bio / bioinformatics community. Nature even wrote a feature article about it a couple years ago: Why scientists are turning to Rust https://www.nature.com&#
63.
Rosalind: A genomics toolkit in Rust running whole-genome pipelines on a laptop(github.com)
185 points by samuell 5mo ago|57 comments
64.
by samuell 5mo ago
I want something like this, but completely terminal based
65.
by samuell 5mo ago
I'm really quite divided about Rust vs Mojo for bioinformatics in the future. The syntax i Mojo really seems to shine a lot ... though I still wonder if the train has already left now that so much bioinfo work is already done in Rust.
66.
by samuell 5mo ago
Gotcha! Though that is not for the self-hosted version IIUC? But yea, rust-chat in a way seems like more of a proper open source project ...
67.
by samuell 5mo ago
Very cool! I have been pretty hopeful about Mojo as I find many of the modern compiled languages these days requires an surprisingly excessive amount of ceremony just to open a file and read it line by line. At least this is the case with G
68.
by samuell 5mo ago
How does it compare to MatterMost [1]? [1] https://mattermost.com/
69.
by samuell 5mo ago
Somewhat related: Show HN: Epiq – Distributed Git based issue tracker TUI https://news.ycombinator.com/item?id=48155570
70.
by samuell 5mo ago
I think this is a cool project. I see a lot of use cases for this, for cases where it is preferable to keep issues local to the repo, distributed via git only, and not the least for all kinds of personal task management. Avoiding the contex
71.
Flux Matching – Generalizing diffusion models to non-scoring func vector fields(twitter.com)
2 points by samuell 5mo ago|0 comments
72.
by samuell 5mo ago
> “People who go all in on AI agents now are guaranteeing their obsolescence. If you outsource all your thinking to computers, you stop upskilling, learning, and becoming more competent.” > – Jeremy Howard, creator of fast.ai This so
73.
Playing freely – and not limiting innovation to what is already best practice(livingsystems.substack.com)
1 points by samuell 5mo ago|0 comments
74.
by samuell 5mo ago
I think the village would be a healthy model for sure. But that is something that was pretty much killed in the modern society as well as most people, especially lower/mid-income workers in larger cities, are spending exceedingly littl
75.
by samuell 5mo ago
It is a bit curious with the Mojo 1.0 beta coincidence, as Pascal was the other langauge with a highly readable and quite simple language combined with performant compiled code without GC. What it lacked was a modern compiler and stack. The
76.
by samuell 5mo ago
As someone who would have strong reasons to invest time in Modular (simple high performant language for implementing bioinformatics scripts), I would say primarily the worry that development might be too tied to Modular, the startup behind
77.
by samuell 5mo ago
The communication had me try to run some very simple python code assuming it of course should run (reading files line by line), which didn't work at all. For me this was a big disappointment, and I wonder how much this has backfired ac
78.
by samuell 5mo ago
Which is probably one of the biggest problem with the outsourcing of parenting for half their awake time that is happening with our established school system. Not that I claim it is super easy to find an alternative on a large scale, but I
79.
Epiq: Distributed Git-backed CLI native issue tracker TUI(github.com)
4 points by samuell 5mo ago|1 comments
80.
by samuell 5mo ago
There is also epiq, which is a bit more bleeding edge but has a more powerful UI story, being a TUI app, providing an issue board in the terminal: https://github.com/ljtn/epiq
81.
by samuell 6mo ago
So the execution model is now even more similar to Go's one, with the M:N scheduling, IIUC? I much like to hear that, as I found Crystal to provide pretty much exactly the same concurrency primitives as Go, but with a much nicer syntax
82.
by samuell 9mo ago
Indeed! I generally like awk a lot for simpler CSV/TSV processing, but when it comes to cases where you need things like combining/joining multiple CSV files or aggregating for certain columns, SQL really shines IME.
83.
by samuell 9mo ago
Did you try https://elicit.org ? I have been impressed by its results. I think this fact stems more from its initial search phase than its pure LLM processing power, but to me it seems the approach works really well.
84.
by samuell 9mo ago
Nice experiment and writeup! On a tangent, nice to see Plasmidsaurus using Emu [1], which has been shown to work great for 16S ribosomal RNA analysis on ONT by basically everyone I've heard who tried it. It has a nice algorithm for pre
85.
by samuell 9mo ago
Curious that this hit the front page. What kind of projects is this software used for?
86.
by samuell 10mo ago
I tried this to try to extract some speech from an audio track with heavy noise from wind (filmed out on a windy sea shore without mic windscreen), and the result unfortunately was less intelligible than the original. I got much better resu
87.
Nvidia aquires SchedMD – developer of Slurm HPC scheduling software(heise.de)
4 points by samuell 10mo ago|1 comments
88.
by samuell 11mo ago
I love Prolog, and have seen so many interesting use cases for it. In the end though, it mostly just feels enough of a separate universe to any other language or ecosystem I'm using for projects that there's a clear threshold for
89.
by samuell 11mo ago
Yea, a bit like a cheating student rote memorizing and copying another students technique for solving a type of problem, and failing hard as soon as there's too much variation from the original problem.
90.
by samuell 11mo ago
I was going to ask about wine support. Anyone tried in Bottles (wine distribution)? I've had better luck with Bottles than plain Wine with other software. Hoping to try soon.

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