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rolph
searching PlanetScale…
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41 ms
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931.
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by
rolph
11mo ago
reprogramming, is not resetting. the "reprogramming" happens constantly, as a consequence of feedback driven regulation, not as a consequence of meiosis. there is a phase of error correction that occurs after chromosomal replicati
932.
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by
rolph
1y ago
no thats wrong. there is a claim that epigenetic mechanisms in bacteria provide weak support for such in humans, not true it was the basis for realizing that epigenetic mechanisms exist, and was central to understanding regulaion of express
933.
▲
by
rolph
1y ago
human gene regulation is dependent on methylation events and acetylation events, as well as conformal events with respect to the strand. there is no meiotic reset to default. you should hang with some oncogeneticists for fresh perspective.
934.
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by
rolph
1y ago
darwin had the idea that many individuals with variation were culled according to relative fitness. mendel later demonstrated that this variation was passed fractionally, to decendants. this was a conserved probability of fixed combination
935.
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by
rolph
1y ago
at this point it seems evident, they should step away and let the task be done by capable hands.
936.
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by
rolph
1y ago
no, no it does not strip protien complexes away from the DNA strand. it involves a localized progression along the DNA surrounded by histones, and regulatory enzymes, displaced from proximity, until the replication fork zooms on through, an
937.
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by
rolph
1y ago
the entire OP displays a lack of knowledge regarding epigenetic mechanisms, as well as a lack ot knowledge base required to make an informed appraisal. the knowledge base required, is extensive for a non biologist, and made difficult to att
938.
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by
rolph
1y ago
plasmids https://en.wikipedia.org/wiki/Plasmid
939.
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by
rolph
1y ago
viewing genetics as dogmatic darwinist purity isnt the state of the art. current genetic theory is a synthesis, loosely referred to as neo-darwinism https://en.wikipedia.org/wiki/Neo-Darwinism
940.
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by
rolph
1y ago
in terse, behaviour is dependent on neural activity; neural activity is dependent on expressivity, and penetrance of genetic constituency. https://en.wikipedia.org/wiki/Behavioural_genetics https://assets.ca
941.
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by
rolph
1y ago
an RNA interference scan of maternal gametic DNA would go a long way toward revealing identified epigenetic modifications; also would not be cheap. this would also be accompanied by interviews, that would reveal high risk factors, as well a
942.
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by
rolph
1y ago
here is some reading for you: https://www.sciencedirect.com/science/chapter/edited-volume/... https://pmc.ncbi.nlm.nih.gov/articles/PMC12204592/ https://sciencevivid.com&
943.
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by
rolph
1y ago
there could be a circular issue here to resolve. 10: print "why do they live so long; because enhanced DNA repair." 20: print "why enhanced DNA repair; because they live so long" 30: goto 10 this begs a tumble into a rab
944.
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by
rolph
1y ago
could be, but i think its similar to a bathroom wall, or physical bulleten board. a publicly facing space with no attribution, that can be linked to, and evade URL based filters of known hate speech projectors.
945.
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by
rolph
1y ago
actual title: Equatorial Atlantic mid-depth warming indicates Atlantic meridional overturning circulation slowdown https://www.nature.com/articles/s43247-025-02793-1
946.
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by
rolph
1y ago
i have win 11 ISOs first curiosity [quickly evaporated] gave way to one purpose; rev eng ing malware in its natural environment.
947.
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by
rolph
1y ago
in the US we have a patchwork of "verbal contract" laws. campaign promises should be held to verbal contract and elections interference by inducement. i.e. if you vote for me i promise you the world, some cheques, and a lot of ugl
948.
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by
rolph
1y ago
gymnastics, shower ads, medical examination, there are lots of things infiltrated by AI that provide visual frames, no need for porn.
949.
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by
rolph
1y ago
a robot that never falls, is a naive goal. a robot that recovers from a fall, is reasonable, and worth a lot more than chasing infallibility.
950.
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by
rolph
1y ago
i think you want a flag register ? not a hardware "bitflag" but a portable software configuration, made simple. [if hexadecimal words are simple]
951.
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by
rolph
1y ago
none of them seem to realize the danger they put themselves in when they wear a ligature of cloth around thier neck, and engage in physical assaults. all they need is to encounter that one guy that throttles someone rather than submitting,
952.
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The One Who Kept VLC Free
(welcometothejungle.com)
3 points
by
rolph
1y ago
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0 comments
953.
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by
rolph
1y ago
repair window screens. mitigate standing water, even sippie holes, or derelict party cups. but save your effort if you live near a pond slow stream, or lake. door discipline, dont keep it open, sweep yourself for piggybackers. electric mosq
954.
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by
rolph
1y ago
alternate, and supplemental: https://en.wikipedia.org/wiki/Restriction_enzyme https://www.sciencefacts.net/restriction-enzymes.html https://microbenotes.com/restriction-enzyme-restricti
955.
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Everything You Ever Wanted to Know About Type II Restriction Enzymes
(neb.com)
1 points
by
rolph
1y ago
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1 comments
956.
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by
rolph
1y ago
dont use randomized fingerprints, spoof actual fingerprints, randomly.
957.
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by
rolph
1y ago
on the one hand, dont pay some taxes. on the other, get a bump, and pay it back with interest. in that frame, it seems like a nobrainer.
958.
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by
rolph
1y ago
i have to question the intent behind obfusicating a camera, and deterring obstruction. now the easiest solution seems to be drilling into the case and destroying the sensor, with epoxy afterward.
959.
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by
rolph
1y ago
ankle monitors are so old and weak. androids are dated sci-fi. now we clamp an exo-hibitor on the condemned, so any movement made with criminal intent will be neuroelectricaly inhibited. after a learning cycle the exo-inhibitor will recogni
960.
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by
rolph
1y ago
portable app, no internet required, is what gets me onboard.
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