robbiep

71 ms·

751.
by robbiep 6y ago
One of the reasons we worked out we could get people through without ventilators was because we ran out of ventilators. And people with COVid are being vented for 2 weeks plus. A normal time (and a time that would minimise Kung damage from
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by robbiep 6y ago
When we keep patients ‘dry’ in ICU we aim to keep their urine output at a level that indicates safe glomerular filtration rates. ACE2 is expressed extensively in renal tissue, so the virus is transported there in the blood, infects cells, h
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by robbiep 6y ago
Prolonged ventilation is damaging to the lungs. But ventilation is not given lightly - usually it is for an acute deterioration and is life saving (ie without it, patient would have died in that instance). Interestingly in COVID it appears
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by robbiep 6y ago
The jury is still out AFAIK
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by robbiep 6y ago
From UpToDate: In the general population without a personal history of VTE, a study involving 1690 unrelated individuals from Europe found a prevalence of FVL of approximately 4 percent, and a study involving 356 individuals from Canada fo
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by robbiep 6y ago
You’re choosing a narrow band of the population. Undoubtedly there are thousands of groups out there who, by way of genotype, phenotype or lifestyle, are at higher risk. Teasing these all out is going to be the work of the next decade. It’s
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by robbiep 6y ago
I also got my first queue set up and running within a reasonable period of time with celery. I have no idea of the internals of RabbitMQ and took longer with celery really (back on python 2.7) but that system has been in prod for 6 years no
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by robbiep 6y ago
Worth looking at - https://en.m.wikipedia.org/wiki/One-electron_universe
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by robbiep 6y ago
I know this is only dealing with a tiny portion of your comment, but why do people think digital prescriptions require a proof of work database, when matching a UDID and changing a 0 to a 1 would suffice?
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by robbiep 6y ago
All cause mortality is down 9% over the last couple of months in Rome (sorry, on mobile, not easy to add reference which I would have to trawl for) - just to get in front of any covid-seriousness deniers, Rome has not been badly hit. In Aus
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by robbiep 6y ago
Hit the web button at the top and then the first link
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by robbiep 6y ago
That’s literally the article?
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by robbiep 6y ago
For a long time ubers have been more expensive in sydney (which is known to be one of their most profitable markets) for many rides than taxis - there is an added convenience of Uber that taxis are only just catching up to (in terms of seei
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by robbiep 7y ago
The virus is causing the pneumonia (which literally means lung inflammation). Although it is possible to get a superimposed bacterial infection over the top of this (to be mildly flippant, double pneumonia) because the lungs aren’t clearing
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by robbiep 7y ago
some partial data: https://www.economist.com/united-states/2020/04/16/could-ame...
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by robbiep 7y ago
my bad
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by robbiep 7y ago
Austria did a relatively large scale antibody sample of its pop (0). Seems to discredit the notion that infections are vastly different than modelling. (0) https://amp.theguardian.com/world/2020/apr/10/
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by robbiep 7y ago
... up until about 15 years ago we only knew of 9 planets so our sample size was pretty small
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by robbiep 7y ago
I hated EM as a student and for my first couple of rotations. I was streaming for surgery and couldn’t understand why Thr emergency department kept making such stupid admissions for us. By the time I’d seen a couple thousand patients in the
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by robbiep 7y ago
The US experience is not good. I’m a resident in Australia. 11 years at university (took some side tracks), $70k in debt for the whole time, now gone, and we are paid between $70-110k a year as interns. Although our training pathways are lo
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by robbiep 7y ago
But azithromycin has an ACE2 inhibitory effect and its use in disease modulation is postulated to decrease viral entry to the cell in a similar mechanism to HCQ, hence the discussion of dual therapy there. The opportunistic bacterial infect
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by robbiep 7y ago
Already happening right? https://www.google.com.au/amp/s/www.bloomberg.com/amp/news/a...
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by robbiep 7y ago
This isn’t easy - ECMO is in (very) short supply, Australia during swine flu had somewhere around 50 nationally (cf 2000 vents) + you need a cardiothoracic surgeon to put it in + nursing care is even more intense than for ventilator care. Y
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by robbiep 7y ago
If you have enough text on your slides that your audience needs to adjust the text size... they aren’t listening to you and you’re writing a textbook not giving a presentation
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by robbiep 7y ago
Droplet infection is only really a problem within a couple of metres - SARS-CoV-2 does not seem to be aerosol spread.
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by robbiep 7y ago
No! It’s bloody useless because you’re not just receiving it through your respiratory passage, but also eyes. And then you touch a surface which someone has put bodily fluids on and put your fingers in your mouth or rub your eyes. Masks are
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by robbiep 7y ago
What are you saying, that thalassaemia is protective against COVID? Thalassaemia protects against malaria because blood cells (the home of the parasite during a phase of its lifecycle) are destroyed up to 3-4x faster than in non-thalassaemi
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by robbiep 7y ago
Medical assistance is ‘supportive’ This means: If you come to hospital, we give you oxygen. Initially through nasal prongs, then progressively through mask and then straight to intubation - ventilator. If the lungs are completely unable to
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by robbiep 7y ago
Masks don’t help for catching the virus (materially) - better to wash hands. Masks do help with curbing transmission from infected, and are also needed for healthcare workers. Please don’t waste masks when you could get significantly better
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by robbiep 7y ago
It’s like that walkthrough of the Chernobyl meltdown from the miniseries. Except it could work. If we insert the control rods now and scram the reactor then we could avoid societal breakdown when hospitals overflow and make the difference b

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