radus

8 ms·

31.
by radus 3y ago
Totally agree with the critique, though it bears mentioning that one way that polars differentiates itself from pandas is the expressions API. See [1] for an example. 1: https://kevinheavey.github.io/modern-polars/metho
32.
by radus 3y ago
That's awesome, thanks for sharing! Though tbh I'm not likely to use it.. it's a bit too magical - though still a delicious hack.
33.
by radus 3y ago
I'm not including parsing time, both pandas and polars versions started from an in-memory data structure parsed from two XML files (low GB range). This is on my workstation with a single Xeon 4210 (10 cores, 20 threads @ 2.20-3.20Ghz).
34.
by radus 3y ago
To add some balance: - I can't rule out that a pandas wizard couldn't have achieved the same speed-up in pandas - polars code was slightly more verbose. For example, when calculating columns based on other columns in the same chai
35.
by radus 3y ago
It allowed me to take some code that reads in a bunch of data and performs a few rounds of some pretty standard operations (groupby, filtering, calculating mean/stdevs) and going from pandas to polars allowed me to go from ~1 minute pe
36.
by radus 3y ago
Many plots contain thousands of data points. Eg: 10 x 100 heatmap which supports sorting by various metadata. This is a common visualization for biological data where your data matrix is samples x proteins, so potentially much larger than 1
37.
by radus 3y ago
Nitrile is a fine default at home and in the lab if you make sure to change your gloves when they are contaminated. You can also double glove.
38.
by radus 3y ago
For most items you don’t need to do anything beyond a scrub and rinse. Others have pointed out that glassware is expensive and sometimes unique. Additionally, if you don’t need much product (eg. you’re screening reaction conditions), you ca
39.
by radus 3y ago
It's easier to re-use if you need the same generated field in multiple places.
40.
by radus 3y ago
No, as I understand it, the Django project's stance on type hints is that they aren't going to be added any time soon, but they are willing to accept small PRs that are needed by external type-checkers on a case by case basis. Det
41.
by radus 3y ago
IMO unlimited needs to be paired more often with a guaranteed or even minimum number of weeks - at least if the intent is for employees to actually take their vacation.
42.
by radus 3y ago
> this looks like one narrow niche knowledge base. I am not expert in this domain, but there are probably some other use cases not covered by existing offerings. UniProt is not niche. It contains curated information about all proteins ac
43.
by radus 3y ago
I agree with your suggestion and would 100% welcome that process - though I don't think they're necessarily mutually exclusive. As I see it, the main difference between the status quo and the more open process you suggest is that
44.
by radus 3y ago
One of my favorite journals. Perhaps of interest to HNers is their fairly active GitHub: https://github.com/elifesciences , and my favorite project of theirs, Lens: https://github.com/elifesciences/lens
45.
by radus 3y ago
Some of the things that peer reviewers do, in my experience, in biology: - question whether or not the conclusions you are making are supported by the data you are presenting - ask for additional experiments - evaluate whether or not your r
46.
by radus 3y ago
How is that different from any profit seeking endeavor? You could write the same company about software companies that don't open source all of their code..
47.
by radus 3y ago
Moreover, pharma companies and academics already do model PK.. it's a huge field of study, not some ignored "broken stair" - there is definitely "serious money" behind this.
48.
The first foldable PC era is unfolding(arstechnica.com)
1 points by radus 3y ago|0 comments
49.
by radus 3y ago
Yep, nice landing page but the component comparisons are beyond disingenuous, as should be obvious to anyone who has implemented such a thing before. If you toss out the additional features, types, accessibility, customizability and composa
50.
by radus 3y ago
Not a Supabase user, but to my knowledge -- no. Except for a set of blessed extentions, Supabase only supports extensions that are written in "trusted languages" (ie. supported by pg_tle), and Lantern is written in C, which is cur
51.
by radus 3y ago
sed 's/doctor/programmer/g'
52.
by radus 3y ago
no
53.
by radus 3y ago
Peewee is excellent! I've especially enjoyed using it with SQLite - there are a number of handy extensions and very good support for user defined functions.
54.
by radus 3y ago
I occasionally do this with views managed by https://github.com/xelixdev/django-pgviews-redux/ .
55.
Redun: Yet another redundant workflow engine(insitro.github.io)
3 points by radus 3y ago|0 comments
56.
by radus 3y ago
This is the first time I've seen this and it looks very interesting -- thank you for sharing! I described my workflow in a different comment on this post, and this seems like something I could port to with minimal changes in code since
57.
by radus 3y ago
The DDA pipeline goes like this: ThermoRawFileParser -> Comet -> [a bunch of OpenMS tools] -> Percolator -> [custom quantification stuff]. The data is mostly derived from chemoproteomics experiments where you have isotopically l
58.
by radus 3y ago
I've considered using Nextflow for bioinformatics pipelines but have yet to take the plunge. At work, I develop a proteomics pipeline that is composed of huey¹ tasks (Python library; simple alternative to Celery) which either use subpr
59.
by radus 3y ago
For me it's more about documenting your components for my team/myself. I guess you can think of it as a framework for creating doc pages with interactive demos of components, as shown in this demo: https://vue3.examples
60.
Unicode/List of Useful Symbols(en.wikibooks.org)
1 points by radus 3y ago|0 comments

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