piyh

14 ms·

1. 151.▲
   by piyh 3y ago

   >"Moreover, the identification of a distinct isoform of PCNA associated with cancer cells has potentially opened a novel avenue for the development of new chemotherapeutics" It is targeting a mutated version. https:/&#x2F
2. 152.▲
   by piyh 3y ago

   Phase 1 trial scheduled to end in March 2024 https://classic.clinicaltrials.gov/ct2/show/NCT05227326
3. 153.▲
   by piyh 3y ago

   Question from a layman: >100% of solid tumors Solid tumors == all cancer, or would something like a lymph node cancer not be included?
4. 154.▲
   by piyh 3y ago

   Once we had a system that allowed notifications on employee changes, and an admin who ticked a fun box that resulted in everybody with an email on their employee profile getting notified in plaintext on SSN changes with before and after val
5. 155.▲
   by piyh 3y ago

   Venvs not being able to be moved to other directories is such a PITA.
6. 156.▲
   by piyh 3y ago

   25k of added consumption saved would be 43k of interest gains in 15 years in his "line always go up" world view. 43k is over 6 month living expense for me, and I get to keep the initial 25k. I wish I would have spent more money i
7. 157.▲
   by piyh 3y ago

   I want to run native containers without the orders of magnitude worse io performance than any other platform
8. 158.▲
   by piyh 3y ago

   I don't think it's a failure if the original claims are showing some kind of promise, science is being done, and the frontiers of knowledge are being pushed forward. In other words, not "Eureka!" but "that's we
9. 159.▲
   by piyh 3y ago

   People have voted with 130 billion dollars a year that Meta ads are an effective means of influence
10. 160.▲
    by piyh 3y ago

    Alpha Phoenix is up there too.
11. 161.▲
    by piyh 3y ago

    David Grusch is literally talking heresay with zero first hand accounts. Heresay is not allowed in courts for a reason. Snowden blew the lid off an international conspiracy, and he had gigabytes of receipts. Grusch has talked to people who
12. 162.▲
    by piyh 3y ago

    We used to, we still do too
13. 163.▲
    by piyh 3y ago

    Unmoving copper also neither repels or attracts a magnet. Eddy currents impede movement of non ferrous metals in a static magnetic field. This looks like slow motion falling or resistance to spinning when the metal is in a fixed field. Th
14. 164.▲
    by piyh 3y ago

    Pentium 4 to 10 GHz, here we come!
15. 165.▲
    by piyh 3y ago

    Porn has been VR, and this an AR machine. This could be the robo-gf bladerunner 2049 experience. You're thinking too small.
16. 166.▲
    by piyh 3y ago

    He's trying to relive his glory days as a Paypal executive.
17. 167.▲
    by piyh 3y ago

    My company rightfully has a bunch of controls to prevent data leakage through things like company API keys being stored on postman servers. They are effectively removing themselves from this company's workflow.
18. 168.▲
    by piyh 3y ago

    Can your tapes self replicate? /s The goal of replacing memory cards is dumb, the tech that enables the storage is a foundational step forward in bio engineering.
19. 169.▲
    by piyh 3y ago

    Direct arxiv link: https://arxiv.org/pdf/2306.15934.pdf
20. 170.▲
    by piyh 3y ago

    Agreed, serverless and monolith are not on the same spectrum
21. 171.▲
    by piyh 3y ago

    Flashback to 3 body problem and harvesting energy from local c.
22. 172.▲
    by piyh 3y ago

    Or be a form of energy harvesting at a microscopic scale
23. 173.▲
    by piyh 3y ago

    Are solar storms an issue for LEO sats?
24. 174.▲
    by piyh 3y ago

    The text to video with a base image seems like a extremely powerful use case to me. Midjourney for the high fidelity "Will Smith eating spaghetti", and continue it with Magvit would yield much better results than the current stat
25. 175.▲
    by piyh 3y ago

    >Lockless is not the same as lock-free Can I get the HN comment length explanation of what this means?
26. 176.▲
    by piyh 3y ago

    Build a platform Recruit free labor Replace them when they stop working
27. 177.▲
    by piyh 3y ago

    In most cases, yes, in all cases, no. There's a lot of variants of "enumerate all devices on a private network if you visit a malicious webpage" exploits. https://medium.com/@brannondorsey/attacking-priva
28. 178.▲
    by piyh 3y ago

    I've only thought about this from the perspective of TMSC fab getting hit with cruise missiles, but I've never gone down the long term impacts of the trade freeze that would happen with China. Decades of globalization having to b
29. 179.▲
    by piyh 3y ago

    Also really depends on what kind of experts you're looking for. 99.99% of the world's experts are not writing in trade publications or scientific journals.
30. 180.▲
    by piyh 3y ago

    Give it 30 years for the open source option to catch up.