peytn

14 ms·

91.
by peytn 5y ago
Pretty much everyone in life sciences/medicine wants people to be healthy. Public health attracts those who have a problem with informed consent. They need to clean up their act ethics-wise. It’s not working in 2021.
92.
by peytn 5y ago
In practice these big trials are run as sloppily as possible to get the desired result. There’s a whole cottage industry of consultants. Think unclear instructions leading to dosing mixups and such. The type of trial you’re proposing is not
93.
by peytn 5y ago
Saudi oil: nothing would happen. It’s a commodity. They’d sell their oil at market price minus epsilon. Regime would be fine. China tariff: they’d devalue the yuan. They already have capital controls that keep money from leaving the country
94.
by peytn 5y ago
I mean, if the app I want is on a single store, do I have a choice? Are users really itching to install the Epic store so they can have more choices? The Epic store will be shoved down their throats. As a user I’m pretty okay with devs not
95.
by peytn 5y ago
Intuitively I think as long as your activation function is sufficiently expressive (e.g. not a step function or something), you should be go to go in theory since that’s what you’re feeding back. Might take a while.
96.
by peytn 5y ago
Realistically, EITC expansion or similar would be the tool if you wanna go that route as it’s more easily modeled than nationwide collective bargaining and is generally considered more efficient than a jobs program.
97.
by peytn 5y ago
I think GP was saying the opposite, i.e. it’s nominally about political power as you said, but in the local context they’re going after white men who have no political power and ignoring politically powerful groups.
98.
by peytn 5y ago
We can create combinatorially many drugs. There are labs that can screen hundreds of thousands of molecules a day. So approving drugs that aren’t proven effective for a disease might reasonably lead to few or no drugs that are effective bec
99.
by peytn 5y ago
Likely years ago somebody at Biogen used a spreadsheet to calculate NPV under a range of scenarios, and from that decided to license this drug from Neurimmune. So it’s this or nothing, unfortunately.
100.
by peytn 5y ago
You’ve hit the three corners of the Fraud Triangle—opportunity, incentive, rationalization.
101.
by peytn 5y ago
I think it isn’t necessarily innumeracy to move past napkin math 18 months on. People have had the time to see the results of several cycles of behavior modification and perhaps aren’t interested in participating further.
102.
by peytn 5y ago
> Marzari stated that she was not overriding Clark’s “freedom of thought and speech.” “There is no requirement that [Clark] change his views about what is best for [Maxine],” she explained. “It is only how he expresses those views privat
103.
by peytn 6y ago
Nujabes kinda popularized the genre as well. It would be weird and unnecessarily racially charged if the author referred to him as a “yellow Japanese man.”
104.
by peytn 6y ago
> any adverse effects would have shown As I understand, the required teratogenicity study in rats with Pfizer is ongoing as of two weeks ago [1]. It’s rather optimistic to claim we’ve seen everything when even animal studies haven’t comp
105.
by peytn 6y ago
The history of medical ethics is interesting. We’ve sort of drifted from pure utilitarianism. One problem is that since everyone dies eventually and our statistics aren’t complete, you can usually come up with ways to justify doing pretty m
106.
by peytn 6y ago
I’ve got a little bit of FDA experience, but of course no COVID-19 EUA experience. Based on what we submitted to the FDA and the comments we received, I would personally think it most likely there were many issues with AZ’s materials, at le
107.
by peytn 6y ago
> “This is a safe and effective vaccine” > Sir John Bell, the Oxford University professor who helped drive the vaccine’s development Since academics traffic in reputation, this is an example of a conflict of interest I think.
108.
by peytn 6y ago
Parent was talking about missed cancers and drug abuse, not suicides. Alcohol sales were up ~20% [1]—that too is hard data. [1]: https://wineindustryadvisor.com/2020/11/16/nielsen-covid-bev...
109.
by peytn 6y ago
I don’t understand your comment. I’m not advocating for more cautious rules. I’m advocating for due process. The rules should be what we feel is necessary.
110.
by peytn 6y ago
The FDA has a process in place as per the Pandemic and All-Hazards Preparedness Reauthorization Act of 2013. If you find that legislation inadequate in some way, I think following due process to change it is the way to go. If how we handle
111.
by peytn 6y ago
The rules do not exist to manage risk. They exist to strike a balance between ethics and risk in emergency situations. If you’d like to change them going forward, feel free to advocate. I think it’s best we stick with our current rules this
112.
by peytn 6y ago
I think the concerns would be around the delivery vehicle, which presumably is some big polycationic lipid thing. From what I can gather, there’s not terribly much info on what’s known about what’s going into people’s bodies, and what info
113.
by peytn 6y ago
Are you in a salaried role with pager duty? Are your responsibilities different from what was advertised? It sounds like you’re okay with pager duty—have you tried asking for an increase in comp? You can probably fix your current plight wit
114.
by peytn 6y ago
> there are plenty of people just waiting to have their anti-vaccine confirmation biases triggered You’re probably right, but if we keep trying to front-run people’s reactions to events over and over again, I’m not sure we’re going to ge
115.
by peytn 6y ago
Keeping on the myth of birth control... > A joint statement from the FDA and CDC clarified that the blood clotting was cerebral venous sinus thrombosis (CVST). I don’t believe birth control is associated with CVST at a rate of 1/100
116.
by peytn 6y ago
If you owned all the gold, people would still want to buy gold. If you owned all the Bitcoin, nobody would want to buy Bitcoin. The only value stored is the network of people pumping it, and the only question is how long it’ll take them to
117.
by peytn 6y ago
I can’t find any engineering job postings on their careers site with the location “Ghana Remote.” Hopefully those roles are coming soon.
118.
by peytn 6y ago
It’s not just “going digital”—the creative act isn’t there. It’s just financialization. The act of taking an artwork to an auction house isn’t something that’ll hold value.
119.
by peytn 6y ago
At the very least, these arguments might be more credible if their pushers disclosed their own financial interests in said valuable assets.
120.
by peytn 6y ago
Dang, I was hoping somebody would’ve come up with something by now before the SEC or whoever does.

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