orra

59 ms·

721.
by orra 5y ago
> Cranelift is much better suited as a jit library than llvm is. Unladen Swallow is seared in my mind. It was a failed project, back in 2009, to improve the speed of CPython by using LLVM as a JIT.
722.
by orra 5y ago
Thanks for the detailed answer.
723.
by orra 5y ago
> SSRIs, which have poor efficacy Sort of. As I understand it, SSRIs have poor efficacy for mild depression, but have better efficacy against severe depression. > CBT are useful interventions that can be easily monitored by physicians
724.
by orra 5y ago
I know Germany doesn't do legal precedent, but is there actually any case law demonstrating works can't be put into the public domain? The idea it can't be done is a trope at this point, but I am frankly skeptical. Moral righ
725.
by orra 5y ago
You're just talking anti vaxx drivel. In reality the risk benefit analysis[1] is clear: the benefits massively outweigh the risks. No vaccine ever stops 100% of infections; stop making unnecessary preconditions. [1] https://
726.
by orra 5y ago
It wasn't a precondition. Compare the approved vaccines now[1] with the archive back in March 2021[2]. [1] https://www.ema.europa.eu/en/human-regulatory/overview/publi... [2] https://web.archi
727.
by orra 5y ago
Intéressant. Sorry, I was being pretty anglocentric.
728.
by orra 5y ago
Exciting that they're using it as a platform to develop other vaccines. But I still maintain the official names are ridiculous. “Vaxzevria” is the trademark used by AstraZeneca in the EU. (As you say, not ChAdOx1.) And yes, the general
729.
by orra 5y ago
> Is it possible that the heavy mutations detected on the A.30 variant also make it less contagious? That wouldn't surprise me. The spike is central to how SARS-CoV-2 is so infectious. If the virus mutates the spike too much, it mig
730.
by orra 5y ago
No, I don't think Comirnaty is any better! I am however relatively partial to Spikevax, aka Moderna: at least Spikevax is easily pronounceable. I suppose you mean the vaccine names are mainly useful for regulatory purposes, because the
731.
by orra 5y ago
Sure, it's hard to test things in real world conditions, but that doesn't mean we should over extrapolate from in vitro findings. In particular, infecting cells easier in a lab doesn't mean the virus spreads from person to pe
732.
by orra 5y ago
> At the time it may have seemed wild, but now it has been proven to be the most effective immunity. It's wild because immunity is useful for preventing infection (also, reducing the severity of infection). There's little poi
733.
by orra 5y ago
Frankly, I think the names are terrible. Great vaccines and all, but terrible branding.
734.
by orra 5y ago
I see where you're coming from, but I don't think this is quite the right distinction. Asymptomatic infection, and presymptomatic infection, are both forms of infection. However, yes, they differ from symptomatic infection in term
735.
by orra 5y ago
Eh, I don't think we can say that with certainty. We know that vaccination is driving down cases. It really feels borderline whether it's enough for herd immunity. (Rich) countries are already rolling out third doses, at least for
736.
by orra 5y ago
Glad she survived. As you say, these things are statistical, not guaranteed, but vaccination massively improves your odds. I know of a few people who can't be older than their ?late fifties? or early sixties? that caught COVID. It was
737.
by orra 5y ago
Lest we despair too much, it's important to remember that vaccination reduces the severity, even if you end up infected. I remember at the start of the year, when the vaccines first came out. A doctor shared some lung X-rays of infecte
738.
by orra 5y ago
Ay, you're not wrong. But even granting them that, they disappointingly say “The Pyright extension for VSCode ... is not guaranteed to be ... maintained long-term.”
739.
by orra 5y ago
Pylance being proprietary is so disappointing, given it's the spiritual successor to Python Tools for Visual Studio (PTVS). PTVS was an open source Visual Studio extension, which later was ported to VSCode.
740.
by orra 5y ago
I don't know what guarantees your typical C++ compiler gives you that those can link together? Regardless, at the very least, you would need to write the headers to be interoperable.
741.
by orra 5y ago
Curious what the applications are. Collections? Would you write a lot of "unsafe" const code, given the chance?
742.
by orra 5y ago
It’s weird to be so focused on infection, when efficacy against severe disease is more practically relevant. And the latter remains high, around 92% or higher, even against Delta. Vaccine protection isn’t binary. Even if you end up infected
743.
by orra 5y ago
Damping is a physics or maths term. To damp means to (steadily?) decrease the amplitude of a wave or oscillation.
744.
by orra 5y ago
We developed several working vaccines, and in record time. A triumph of scientific engineering. I too am very hopeful for mRNA vaccines, although I don't know how much I should temper my expectations. The idea of curing certain cance
745.
by orra 5y ago
> Oh, I didn't know that. In fact, F# has been open source longer than Roslyn (the C#/VB.NET compilers) and .NET Core! There used to be a funny split in the repos: Microsoft had their own visualfsharp repo, and there was a bles
746.
by orra 5y ago
Ah, that's interesting. I'm a huge fan of F#, but I had the advantage of knowing .NET first.
747.
by orra 5y ago
Yeah, sorry, doesn't sound like fun.
748.
by orra 5y ago
Ah, didn't realise. Good they didn't ban it, but then that's still a clear failure of public health messaging. In exchange for falling behind on vaccination, Australia had some rather strict lockdowns (especially for the post
749.
by orra 5y ago
Where Australia really messed up was basically stopping use of AstraZeneca entirely (IIRC). Blood clot risk is much higher the younger you are[1]. It would have been far better to continue using AstraZeneca, but limit it to a certain age an
750.
by orra 5y ago
Absolutely agreed, morally it's the right decision. I was just focusing on the law because copyright expansionists have a lot of institutional capture, or at least the ear of legislators. So even though the intention of the Directive w

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