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opticfluorine
searching PlanetScale…
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8 ms
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31.
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opticfluorine
4y ago
Yes, with a powerful enough source you can resolve protons, that's true. They didn't make such a claim - they listed a run-of-the-mill instrument in their methods section that would not have been capable of this.
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opticfluorine
4y ago
Sure. But in this case there was no claim of a sufficiently strong X-ray source for this, so it fell flat on its face.
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opticfluorine
4y ago
Typically not on their own - it's very easy to calculate an optimized structure that is incorrect, so you typically want some sort of justification for your structure. Typically you would be calculating one of these geometries along th
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opticfluorine
4y ago
That's unfortunately all too common of a story. And with the way peer review works - where the leaders of any niche topic are the ones who will be asked to peer review articles in the same area - the system makes it very easy for an es
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opticfluorine
4y ago
Same here - I went into science thinking that it would be all about trying new ideas and pushing the boundaries of what we know. And while in a certain sense that is still present, it takes a back seat to the perverse incentives you describ
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opticfluorine
4y ago
These aren't protein crystal structures, they are metal-organic frameworks (MOFs), so AlphaFold probably wouldn't work well on these ones. It would be really interesting to see an equivalent model trained to predict these structur
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opticfluorine
4y ago
While pursuing my Ph.D. in chemistry, I was asked to peer review an inorganic chemistry publication in which the author attempted to fake crystallography data. In this case the telltale sign was that they left the hydrogen atoms in the stru
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opticfluorine
7y ago
I was reprimanded for using PuTTY to log into a remote server for a course I was taking through the local community college in high school. The head IT person said that the white text on black background looked too much like "hacking&q
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opticfluorine
7y ago
It's not that the dark matter distribution is isotropic (it's not, as you note). Think of it like this: locally for a given object in the universe, we can work out the amount of dark matter necessary to describe one of its anomalo
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opticfluorine
7y ago
The issue is that strncpy doesn't guarantee that the destination string is null-terminated after a copy, particularly in the case where n is shorter than the original string, so you could run into overflows if you then ran strlen() or
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opticfluorine
7y ago
Yes, and interestingly, because even when used correctly they "complicate audits". This is an interesting use of preprocessor macros, I'm strongly debating introducing something like this at work.
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opticfluorine
7y ago
It's a native frontend, using SDL2 for windowing/audio/input/etc and Direct3D 11 (via SharpDX) for rendering. Backend targets .NET Core and is meant to run in a container on Linux.
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opticfluorine
7y ago
I think you might be right about the popularity. Major commercial MMOs are deriving revenue from either subscriptions or microtransactions, with the latter becoming much more common (and requiring a far larger userbase to maintain profitabi
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opticfluorine
7y ago
This really resonates with me. My big motivator has always been the challenge of all the different technical details. Persistence was certainly a fun one, though I stuck with a RDBMS instead of going the NoSQL route. It's why I'm
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opticfluorine
7y ago
Embedded development is fascinating. I work in embedded professionally and what I've always enjoyed about it is working closely with the hardware engineers (this for a project where the hardware is designed and built in-house). It'
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opticfluorine
7y ago
What a cool thing to be working on! What scale does your pilot installation produce at?
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opticfluorine
7y ago
Thanks! It's very fulfilling. Part of me always feels like I should be working on something else that I could eventually monetize. But this has been my passion project for a long time, and I've learned so much - both now and back
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opticfluorine
7y ago
I've been telling myself that I'll finish one day too, and now on my eighth attempt, I think I can pull it off. Learning to manage long-term projects has definitely helped me with that.
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opticfluorine
7y ago
In my free time I've been working on a 2D MMORPG engine in C#. I'm working on the networking code right now, working toward being able to connect and move around the game world. I'm enjoying the network code, but I'm re