nkrumm

10 ms·

31.
Understanding Amazon's Income Tax Bill(sccinsight.com)
2 points by nkrumm 7y ago|0 comments
32.
by nkrumm 7y ago
UW Laboratory Medicine | ONSITE (Seattle, WA) | Full-Time Our department maintains all clinical testing and laboratory operations at the UW Medical Center, from sample collection to analysis and final reporting. We employ over 900 people an
33.
by nkrumm 7y ago
UW Laboratory Medicine | ONSITE (Seattle, WA) | Full-Time Our department maintains all clinical testing and laboratory operations at the UW Medical Center, from sample collection to analysis and final reporting. We employ over 900 people an
34.
by nkrumm 7y ago
Fully agree— routine is important starting around 4-6 months. As is often said, well rested babies sleep better. I also recommend “Happiest Baby on The Block” by Harvey Karp. Read one or two of these types of books but don’t go overboard.
35.
by nkrumm 7y ago
To some extent there is some legislative action (particularly at the state level) that addresses this. The term commonly used here is “Balance Billing”, though that refers to a variety of “surprise” bills.
36.
by nkrumm 7y ago
MD here. It's "not done" because it could hurt you. Here's the Bayesian argument: - Let's assume a lab test (or imaging test) has a 1% false positive rate and 100% sensitivity (that would be pretty good for many tes
37.
by nkrumm 7y ago
UW Laboratory Medicine | ONSITE (Seattle, WA) | Full-Time Our department maintains all clinical testing and laboratory operations at the UW Medical Center, from sample collection to analysis and final reporting. We employ over 900 people an
38.
by nkrumm 7y ago
GitHub: https://github.com/Piezoid/pugz . From the readme: "Contrary to the pigz program which does single-threaded decompression (see https://github.com/madler/pigz/blob/master/
39.
Parallel decompression of gzip-compressed files(arxiv.org)
3 points by nkrumm 7y ago|2 comments
40.
by nkrumm 7y ago
UW Department of Laboratory Medicine | Data Scientist | ONSITE (Seattle, WA) | Full-Time Our department maintains all clinical testing and laboratory operations at the UW Medical Center, from sample collection to analysis and final reportin
41.
by nkrumm 7y ago
Fascinating. For some interesting US history on the topic, see: https://www.fhwa.dot.gov/infrastructure/right.cfm In particular I found this interesting: "[...] most American cars produced before 1910 were made wi
42.
by nkrumm 8y ago
HIPAA does not explicitly call out genetic/genomic information as one of the oft-cited 18 elements of protected information [1]. However, genetic/genomic information is considered to fall under the 18th element, and HHS states tha
43.
by nkrumm 8y ago
UW Department of Laboratory Medicine | Data Scientist | ONSITE (Seattle, WA) | Full-Time Our department maintains all clinical testing and laboratory operations at the UW Medical Center, from sample collection to analysis and final reportin
44.
by nkrumm 8y ago
Encryption is an "addressable implementation" in the final Security Rule [1]. Practically this means you are not required to encrypt your data (e.g., between LB and VM) "if the entity decides that the addressable implementa
45.
by nkrumm 8y ago
Note that these companies are not doing DNA microarrays in the sense you're describing (which is for quantifying gene expression by mRNA level). RNA-seq is (now) arguably better for this purpose as well (better dynamic range, primarily
46.
by nkrumm 8y ago
It's true that these companies are not offering "sequencing" per se but rather are genotyping commonly polymorphic SNPs using an array or other genotyping method. These SNP arrays, however, are exceedingly accurate and repr
47.
by nkrumm 8y ago
The posted text is actually a series of "dot phrases" or "smart texts" (aka templates in EHR speak), _not_ actual notes. Mostly these are inserted into clinical notes to achieve a certain level of documentation; typicall
48.
by nkrumm 8y ago
Clinical history, some labs, and imaging are typically used to diagnose. In adults, CT scan has the highest sensitivity and specificity (0.96 and 0.96); better than ultrasound. The difference is not as pronounced in children (smaller abdome
49.
by nkrumm 8y ago
Also ndscheduler: https://github.com/Nextdoor/ndscheduler/
50.
by nkrumm 8y ago
The limiting factor is not the spots for medical students, but rather for residents and fellows, who are primarily funded through medicare/medicaid and the VA. An interesting post on this is here, although it somewhat contradicts the p
51.
by nkrumm 9y ago
Even if they do not directly pass this on to patients, cheaper generics will benefit patients in terms of their availability. I recently was involved in a case where a flucytosine (an old, generic anti-fungal) was considered for a patient,
52.
by nkrumm 9y ago
> and the remaining third perish due to the failure of one or more other organs. One of these organs is the heart-- the seasonal variation in influenza actually overlaps with an increase in acute myocardial infarction (AMI, or a 'he
53.
The Box-Cox Transformation(statisticshowto.com)
1 points by nkrumm 9y ago|0 comments
54.
by nkrumm 9y ago
Perhaps not exactly "junk dna" but you are right in your thinking about gene duplications... duplications are thought to promote "neofunctionalization" (a new function) or "subfunctionalization" (specialization
55.
by nkrumm 9y ago
This is an interesting study, and I highly encourage everyone to also read the accompanying editorial, which raises some important methodological shortcomings. See here: https://jamanetwork.com/journals/jama/fullar
56.
by nkrumm 9y ago
It's worth pointing out that that the Deutsche Bahn (German Rail) has been providing this sort of service for at least a decade (I remember seeing them parked outside of train stations in 2008): https://www.callabike-interak
57.
by nkrumm 10y ago
The underlying biology of spermatogenesis is also involved. As males age, the germ cells (~stem cells) that produce sperm are continuously dividing. One of the daughter cells from the division becomes sperm, the other continues on as a germ
58.
by nkrumm 10y ago
The US does vaccinate more than other countries, but it is not 4-fold higher. See this very interesting infographic: http://www.bmj.com/content/351/bmj.h5966/infographic By age 6, the standard vaccine schedul
59.
by nkrumm 10y ago
Hard to tell exactly what this entails, but there is a very functional low-cost solution already on the market called the Pocket Talker ( https://www.amazon.com/Pocket-Talker-Ultra-System-Headphone/... )
60.
by nkrumm 10y ago
Yes-- the inheritance of mtDNA is maternal, but interestingly not 100% of her children will inherit the disease. This is because the mother will have a mix of mutated (diseased) mtDNA and wild-type (healthy) mtDNA in each of her cells, incl

More ›