nextos

67 ms·

961.
by nextos 3y ago
Immunotherapies are still immature but far from snake oil at this stage. They routinely achieve miraculous remissions but also lead to many adverse events. For most late stage tumors, chemotherapy will only, at best, increase life expectanc
962.
by nextos 3y ago
HtDP is a great book, but probably too elementary for the average HN reader looking to begin with SICP.
963.
by nextos 3y ago
With one of the third party cases, such as those from Akasa, they are nice inexpensive fanless machines with excellent Linux support and low power consumption.
964.
by nextos 3y ago
I would also add that the tech VC scene in Stockholm is really good considering the size of the country and its economy.
965.
by nextos 3y ago
I also found it a bit too philosophical in the sense that we can already explain a lot of the variations in outcomes to infection. For example, HLA/MHC is a family of genes tasked with the presentation of antigens (e.g. chunks of prote
966.
by nextos 3y ago
Something important to note is that the authors use normalized compression distance (NCD). NCD is a way to approximate Kolmogorov complexity. This is a pretty old idea, see [1,2]. Old but still very useful, like perceptrons. [1] Li and Vita
967.
by nextos 3y ago
In practice, mainstream distributions do not offer ready-to-use zero-conf sandboxing for userland applications. There are of course exceptions, like those using Flatpak, but what I would like to see is Firejail/bwrap applied to all bin
968.
by nextos 3y ago
I know, I maintain quite a few items in NixPkgs. My point is that Linux distributions are not taking sandboxing seriously compared to mobile or macOS, and this is a big security issue. E.g., if one runs a compromised binary, such as PyTorch
969.
by nextos 3y ago
It does, but it is far from seamless / widely used. It is a little bit more than firejail packed for NixOS.
970.
by nextos 3y ago
It's actually annoying NixOS doesn't offer good default sandboxing. Sandboxing should appeal to the Nix crowd, but somehow it's not been integrated yet. AFAIK, GuixSD is working on sandboxing. In general, sandboxing is pretty
971.
by nextos 3y ago
Sad news. NUCs could have been an excellent platform if they had tried to work a bit more on cooling. On third-party cases, NUCs were great. But on stock cases, some models were too noisy. Still, they provided great value. Nonetheless, I ag
972.
by nextos 3y ago
And hardware switches.
973.
by nextos 3y ago
That's right, but at the same time Flux, the default choice is not mature at all compared to JAX. So that advantage is only on paper. I would really prefer to use Julia, I actually dislike Python, but it's unrealistic to implement
974.
by nextos 3y ago
I know about this. It's heading in the right direction, but still lacks many Gadfly features, let alone ggplot2 ones.
975.
by nextos 3y ago
There's still one major bottleneck. There's no TF / PyTorch / JAX replacement. For small things, interop with R is good, so one can defer things to R packages and get access to a great set of functionality.
976.
by nextos 3y ago
The best plotting APIs I have seen are those from MATLAB and Mathematica. I have used Makie a few times, and it is very flexible and well designed. I am hoping they provide a declarative API that emulates Gadfly more closely. Gadfly is grea
977.
by nextos 3y ago
There's also TrueSkill, by Microsoft Research, which turns Elo into a proper generative model: https://en.wikipedia.org/wiki/TrueSkill It'd be definitely interesting to see a book review site like this. In th
978.
by nextos 3y ago
Program = Proof, Samuel Mimram: https://www.lix.polytechnique.fr/Labo/Samuel.Mimram/teaching... . Also available as hardcopy in Amazon.
979.
by nextos 3y ago
> If you want a sandbox on NixOS, your options are still [...] Exactly, I have brought this up in the Nix forum a few times, but developers don't seem to see the value. Really frustrating and a bit ironic given that sandboxing shoul
980.
by nextos 3y ago
Yes, two extra notes on this: 1. Weakly informative priors can be good to regularize and stabilize inference in scenarios with a low amount of data. 2. In case of the review scenario presented by the OP, a hierarchical model could be even b
981.
by nextos 3y ago
You could try this one: https://hastie.su.domains/CASI_files/PDF/casi.pdf However, IMHO many things come more naturally in a Bayesian setting, such as hierarchical models.
982.
by nextos 3y ago
See this MLSS '20 presentation and all recommended bibliography [1], in particular top left box in slide 123. For rigorous modeling, Gelman et al. books are great [2-3]. [1] https://drive.google.com/file/d/1lP
983.
by nextos 3y ago
Kanerva associative architectures have one extra basic operator not found in classical NNs: https://redwood.berkeley.edu/wp-content/uploads/2021/08/Modu...
984.
by nextos 3y ago
Also, really important to refer to Boyd's prequel book, which is much simpler and can be read by anyone here without any prior background: https://web.stanford.edu/~boyd/vmls It has tons of code and exercises in
985.
by nextos 3y ago
Yes, AFAIK to regularized regression which you would typically use in problems with more variables than instances, such as GWAS.
986.
by nextos 3y ago
There was a NIH moratorium, but it was lifted in 2017. I don't agree about the point of virology being just about studying gain of function. There are tons of things you can study in virology without needing to create novel viruses.
987.
by nextos 3y ago
I think it is also worth adding that there is good evidence of some lab leaks that caused pandemics in the past. See for example: https://en.wikipedia.org/wiki/2007_United_Kingdom_foot-and-m... In my opinion, gain of f
988.
by nextos 3y ago
I meant it's nothing to brag about. I agree that in many situations, it'd be inconvenient to own so few items as it'd leave you unprepared for e.g. emergencies. But if you are renting a condo downtown, as it was my case, you
989.
by nextos 3y ago
I relocated and I no longer have any hobbies that involve tools. For a different lifestyle, this list would be much longer and that is fine. There is nothing special about having just 100 items.
990.
by nextos 3y ago
I've done this, and it's very liberating. Basically, all things I own, including consumables, fit inside a small Org file. It's less than 100 items. I went this route because I wanted to emphasize some good habits, and de-emp

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