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momojo
searching PlanetScale…
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31.
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by
momojo
3mo ago
I'm no fan of Facebook or its social effects but I can't deny the wonderful downstream effect of their open source. Popular microscopy models like Cellpose[0] have leaned heavily on the cornucopia of open and SOTA power. I have no
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by
momojo
3mo ago
PSA: Apple menu > System Settings > Accessibility > Motion These cool demos come up now and again and it always takes me a minute to remember I have reduced motion. But for that minute I was disappointedly clicking around thinking
33.
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by
momojo
3mo ago
I got chills reading this. The last time I felt this way was reading "Project Hail Mary" and that was for a fictional cell! It's crazy to me that we are still discovering these microscopic yet crucial parts of nature around u
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by
momojo
3mo ago
Seems like one of those situations where the outcomes should be measured, not the implementation. If you've created a product that is leading to hundreds of hours of wasted time (and the users themselves are sick of the amount of time
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by
momojo
4mo ago
I've had so much fun writing small apps in pure JS and HTML witj Gemini (no harness or agent, just the free web chat) because it's forced me to keep my index.html below 1000 lines. I love the forced constraints. It's liberati
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by
momojo
4mo ago
How long has this been your daily driver? How has this setup worked for you compared to enterprise models? Which models?
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An exhaustive review of design tool hover areas
(tldraw.dev)
2 points
by
momojo
4mo ago
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0 comments
38.
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by
momojo
4mo ago
Surfacing for the thread: Armin Ronacher's "Absurd Workflows: Durable Execution With Just Postgres" https://lucumr.pocoo.org/2025/11/3/absurd-workflows/
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by
momojo
5mo ago
Poetry. I'm not Buddhist but I find the 'metaphysics' of their prayer wheels fascinating.
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by
momojo
5mo ago
Add microgpt to that list
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by
momojo
5mo ago
And you get sandboxxing for free! My company got tailscale recently, and its just the final cherry on top: `tailscale serve` my `/tools`, and I don't even have to worry about auth!
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by
momojo
5mo ago
Hash tables are one of those miraculous data structures that, once grokked, take you up a step-function in understanding modern computer science. I'm not talking about the 2018 leetcode meme of "Just solve everything in a hash tab
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by
momojo
5mo ago
I might have to look into mojo. What's "alignment" in your context. In bioimaging it usually refers to aligning something to a reference atlas (like the Allen Reference Mouse Brain Atlas) or aligning two microscope channels (
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by
momojo
5mo ago
Sorry, I'm reposting a comment I made yesterday that seems fitting: > This reminds me of Antirez's "Don't fall into the anti-AI hype". In a sentence: These foundation models are really good at optimizing these ex
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by
momojo
5mo ago
When exploring a new idea or tool, my go to prompt is ``` In a single index.html, no dependencies, sparse styling, create an app that <idea> ``` Even before AI, it's how I built small tools, and there's something lovely abou
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by
momojo
5mo ago
I work in bioimaging. What kind of bioinformatics are you doing that requires mojo level power?
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by
momojo
5mo ago
I need to hear more stories, I'm begging
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ZAYA1-8B: Frontier intelligence density via 0.7B active MoE trained on AMD
(zyphra.com)
1 points
by
momojo
5mo ago
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0 comments
49.
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by
momojo
5mo ago
1. I admit my job is not a good sample of 'job most mortals work' 2. I still think 'most mortals' software devs aren't Antirez, and work in industries or fields that still require a human to bridge the ambiguity gap
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by
momojo
5mo ago
> Models are starting to get good at ambiguity That's fair, and something I've observed too. I wish I had written "the rest of us shouldn't freak out and quit software today". But here's another data point:
51.
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by
momojo
5mo ago
This reminds me of Antirez's "Don't fall into the anti-AI hype" [0] In a sentence: These foundation models are really good at optimizing these extremely high level, extremely well defined problem spaces (ie multiply matr
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by
momojo
5mo ago
Check out Airflow and Dagster. I've used Dagster but I can't compare to airflow. But in terms of DX, I've found Dagster pretty easy to use. Instead of writing their own DSL, they have a python library that lets yo tag your pr
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by
momojo
5mo ago
Is this a demo? A hobby? How long have you been at this?
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by
momojo
5mo ago
Thanks for the story! Was this company similar to Plasmidsaurus in terms of industrial-scale sequencing?
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by
momojo
5mo ago
I disagreed, then re-read your post, then re-read the OP, and now I've come full circle to apologize; I think you make a fair point. I work at a biotech. We spent who knows how much time and money trying to develop a 'lab technici
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by
momojo
5mo ago
I know I'm bandwagoning but just to make sure the signal beats the noise: - This looks like vibe-code + fake github stars - There's a difference between "Summarize this verbose report from my the PM so I can get the gist&quo
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by
momojo
6mo ago
How did you eventually get funding after those initial rejections? What changed?
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by
momojo
6mo ago
I was wondering the same thing. Maybe with the way gemma4 and intelligence density is going, they don't predict the need for NPU's?
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by
momojo
6mo ago
I bet it's more about what he didn't do. Like how a stable marriage seems boring but is the accumulation of many many right (by necessarily genius) decisions.
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by
momojo
6mo ago
I'm all aboard the "Apple is simply waiting for the models to get dense enough to run on their hardware" hype train. They're poised to consume the market for the "I want AI, but I don't want to sell my soul&quo
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