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mft_
searching PlanetScale…
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43 ms
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661.
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by
mft_
2y ago
I’m struggling to understand what you are advocating for in practice. What was such a reconfiguration of the economy actually mean in real terms?
662.
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mft_
2y ago
A data point on this: post-Brexit the UK Government has been doing their best to agree trade deals with countries around the globe. There is (for obvious reasons) significant interest in a trade deal with the United States, but a big fear (
663.
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mft_
2y ago
Honestly, if you’ve accurately reproduced your prompt, I had trouble interpreting it initially too. “written on it in mirror writing” is quite ambiguous. Are the letters reflective, but on my side of the door? Is there a mirror with handwri
664.
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mft_
2y ago
> But it is. Tyrants round up women and children and execute them. That's just a difference in methods. > People talk as if insurance companies should spend unlimited resources on every person. You're right that US healthcar
665.
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mft_
2y ago
The actions of his company —which he led and dictated policy for— can be considered evil by a reasonably dispassionate measure - they deliberately caused undue suffering or shortened the life of countless thousands of vulnerable people. I (
666.
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mft_
2y ago
> similar stings :)
667.
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mft_
2y ago
I'm sorry, but for industry-sponsored trials your figures are off by up to an order of magnitude, despite the numbers in the (18 year old) reference. Phase I: a small biotech I know of in oncology has phase I costs in the order of $50
668.
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mft_
2y ago
No need for anger - I think we're mostly in (violent) agreement here. :) Maybe the one area we would significantly disagree is that I don't think it's simply that "the people working on it are not smart enough and are m
669.
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mft_
2y ago
It doesn’t (have to) cost billions to bring a (successful) drug to market. And if you pick a single successful example that was discovered in academia, was spun out into a small focussed biotech, and was in a disease area that didn’t requir
670.
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mft_
2y ago
They’d better hope Rainbolt doesn’t take on the challenge…
671.
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mft_
2y ago
> And so, they give the market what it buys. Simple as. It's not this simple. Marketing isn't just about making an existing product attractive to consumers - it's also about creating new products and even new product categ
672.
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mft_
2y ago
I think you're wrong about the food industry not slowly harming people, for two reasons. 1) For "unhealthy" food (i.e. not something that's acutely poisonous) the link between ingestion and harm is in the long-term; it w
673.
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mft_
2y ago
I think you've got the wrong end of the stick. I'd frame it as: people who want to get stuff done and who can't or don't want to have to fight or troubleshoot their software or the system it runs on will often have
674.
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mft_
2y ago
I mean, it's not fully wrong, although the "please die" might be harmful in some circumstances. I guess the main perceived issue is that it has escaped its Google-imposed safety/politeness guardrails. I often feel frust
675.
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mft_
2y ago
I guess because that seems the path of least resistance within the existing Python world.
676.
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mft_
2y ago
I often muse over there not being a VB-alike approach for Python. It would surely be reasonably straightforward to automate the creation of the GUI boilerplate code from a form designer, and then within an accompanying IDE hide most of th
677.
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mft_
2y ago
This is a very similar concept (the font encoding, not the shaders) to how it was possible to draw little 8x8 sprites in BBC Basic. Brings back memories of drawing pixels on graph paper and mental arithmetic… oph… about 35 years ago!
678.
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mft_
2y ago
Same (except the left-handed challenges) - I have a pair that were probably <€10 on AliExpress, are good enough , and get used all the time.
679.
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mft_
2y ago
Do we understand why? As in, what’s the mechanism behind the ‘changes in metabolism’?
680.
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mft_
2y ago
I wonder whether successful Chinese car companies are currently thriving thanks to their implementation of a collaborative trust and common cause culture? Or maybe there’s a little more to it…?
681.
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mft_
2y ago
Ah, thanks for clarifying - I've only ever seen one of those in a hardware store, and never heard of anyone having one in a hobby workshop! Out of interest, which system do you have which allows a jigsaw and router to use your track?
682.
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mft_
2y ago
(I’m not sure if there’s an established name for this but) What you’re doing isn’t just calling the concept idiotic, but assuming that a whole chain of people involved —presumably including domain specialists, financiers, banks, whoever— ar
683.
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mft_
2y ago
A few thoughts: * Circular saw: a basic hand-held circular saw that can cut through stuff. * Track saw: the cousin of the circular saw; comes with (essentially) a big metal ruler which the hand-held saw part 'locks' into. This me
684.
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mft_
2y ago
Try Steve Ramsey: https://www.youtube.com/channel/UCBB7sYb14uBtk8UqSQYc9-w He's got a very nice approachable style (almost the Bob Ross of woodworking?) and has some great beginner videos, including guidance on wh
685.
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mft_
2y ago
> Apple's approach to hardware design warrants criticism. By creating GPUs with limitations that hinder standard functionalities like tessellation shaders and using non-standard page sizes, Apple places unnecessary obstacles in the
686.
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mft_
2y ago
I've started and re-started Factorio several times, and always enjoy it... up the point where an automated train network is necessary. Here, I always run into problems, and no amount of researching or fettling of the setup seems to gu
687.
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mft_
2y ago
You're right that drugs are generally more expensive in the US, but it's not because "the US has to pay top dollar to subsidize the world's drugs". It's simply that companies charge more in the US because they
688.
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mft_
2y ago
Same here; except I'll recline after dinner on long-haul flights, because that's the point virtually everyone does, especially when the lights are dimmed. I would never recline on <4 hour flights, and am irked by those who do.
689.
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mft_
2y ago
You're not wrong, but I think there's at least a couple of orders of magnitude of awkwardness between the Airpods and the the Vision Pro that will have to be overcome, before the VP becomes mainstream.
690.
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mft_
2y ago
> It doesn't matter if you can in theory stop but not do it or if you cannot physically stop It matters a lot, if you want to use the term "addiction". Addiction has many definitions, but usually it involves a habit or com
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