memling

16 ms·

121.
by memling 5y ago
> (which haven't shown any correlation to inflation since the 80's) Side question: how do we calculate that correlation? To clarify, I understand that you can take two sets of observations and calculate rho, etc. What I'
122.
by memling 5y ago
> I can't imagine I was the only one. I'm sure not, and hopefully the description I provided isn't a blanket one. And, to be clear, I'm also not trying to say that working for any of those organizations is per se u
123.
by memling 5y ago
> Many years ago a colleague who works in defence told me about a job posting he'd seen but was having a moral struggle with. This is a good struggle to have. What's ironic in many cases is that we don't experience these
124.
by memling 5y ago
> Simple: The efficiency of the C4 carbon fixation would be of little benefit to the plant itself. Evolution optimizes for the benefit of the gene-bearer. I don't know if this is a good example, but suppose for argument's sake
125.
by memling 5y ago
> #2 seems your goal, because you did mention "slow decay", but slow decay is still decay, it doesn't matter whether a tree takes 25 or 50 years to decay, all the CO2 it absorbs will eventually release back to atmosphere,
126.
by memling 5y ago
> A better question might be "Why are you interested in building X for Y industry?" If the JD is building X for Y industry, I'd think a cover letter might address this. Sometimes, of course, we're in the position of
127.
by memling 5y ago
> What is the response rate to those postal mails you send? And who do you address them to (do you find the name of the recruiter or just address it to the general company) I don't do this often, so I'd be wary of reading in to
128.
by memling 5y ago
> I'd also like to see cover letters replaced by something more useful for both parties, like a small set of direct questions to answer. This "small set of direct questions," in my opinion, is implicit in the job descripti
129.
by memling 5y ago
> It almost sounds they were stuck writing C++98 code and instead of moving their coding standard to C++17, they chose to rewrite in D. I think they started their port before C++17 was standardized: > Also in 2010, a couple of us (PAJ
130.
by memling 5y ago
> I read a paper somewhere along the line that claimed that DNA itself shows evidence of having evolved - the 3-pair codons that have some error-correcting capacity evolved from single-pair codons. When I write that down it seems wrong,
131.
by memling 5y ago
TIL--thanks a bunch! I've been glad to see some related threads come up on HN lately on this issue, and it's been a fruitful source of (hopefully) intelligent distraction.
132.
by memling 5y ago
> Its not even a full clue, it's a 'possible clue'. Sure. I said it elsewhere in another thread, but I think the bridge from physics to chemistry, while quite fantastic, is a lot easier to swallow than the bridge from che
133.
by memling 5y ago
The article describes a few interesting things, among which is a scenario in which guanine is added to RNA to improve its adhesion to the lipid layer. One such example they noted was a G-quadruplex. Do we see/have other examples?
134.
by memling 5y ago
I moved from software development (focusing on data binding through specification interpretation and code generation) to systems engineering for an industrial precision equipment manufacturer and then back into programming and project manag
135.
by memling 5y ago
These are good comments and resources; thanks! I'm a bit out of my depth in the papers, but reading through them gradually and trying to absorb them. Again, please bear with me--this is not an area in which I have much experience. A
136.
by memling 5y ago
That's an interesting point, thanks. Please pardon some ignorant questioning. How far down does this apply? E.g., do amino acids come basically for free in the same way? If not, what's the bootstrapping process like, and how rando
137.
by memling 5y ago
Can you elaborate on this further? Why don't the laws of probability apply to chemistry?
138.
by memling 5y ago
> levels.fyi has ranges for metro areas and mostly aligns with what I said. Are those numbers staff-reported or business-reported? Do you know how they compare, for example, to studies that businesses do when deciding how to set their p
139.
by memling 5y ago
> Some nights I lie awake staring at the ceiling, wondering if I've wasted my time learning something as vapid and meaningless as computer science. The first instinct I had when reading this was to say that had I known that computer
140.
by memling 5y ago
> Yes, the whole premise is very US-centric. It's actually even more localized than that: the vast majority of places in the US don't pay that much. Silicon Valley, NYC, and some other metros will have higher ranges, of cours
141.
by memling 5y ago
> I really don't understand this pineapple on pizza meme. I think it's delicious! Arnold has an opinion.[0] [0] https://www.youtube.com/watch?v=pKV74qkokmk
142.
by memling 5y ago
> Do you think a software engineer degree is worth it given my current experience? I'd echo any others who say that a degree is worth it. S/W engineering, maybe, maybe not. A degree is a signal you can stick at something for
143.
by memling 5y ago
> Instead one should write tooling that produces decoders that preserve the original encoding of signed data. That's an interesting idea. How do you evaluate the tradeoffs in this design? I.e., what does it buy you compared to say
144.
by memling 5y ago
> Maybe you can answer a question I've had about ASN.1. Long time ago, Marshall Rose had harsh things to say about the ASN.1 macro facility like "buried semantics"[1]. Do you know what he meant? My guess is that his compla
145.
by memling 5y ago
> In the asn1 readme, and in some comments in these threads you mention the perils of the tag-length-value scheme, but you never seemed to explain whats wrong with it? Not OP, but one of the challenges is that definite-length encodings l
146.
by memling 5y ago
> Part of my curiosity stems from Apple using it as part of their bootable file-format: https://www.theiphonewiki.com/wiki/IMG4_File_Format I could only speculate, but I wonder if part of the reason is that DER is c
147.
by memling 5y ago
> What’s so great about ASN.1 and it’s encoding rules is that anyone writing type-length-value serialization for networking purposes, for example[1], is basically independently reinventing ASN.1 because it’s so fundamentally optimal. The
148.
by memling 5y ago
> Is this really the main difference between ASN.1 and Google protobufs, that one is managed by a private corporation and the other by a standardization organization? Can they otherwise be used "interchangably" in designing int
149.
by memling 5y ago
> In terms of tooling, there’s excellent tooling for ASN.1 for C and C++ and maybe some other languages. There’s excellent tooling for protobufs for a handful of languages too, but they’re different sets, so in practice what languages yo
150.
by memling 5y ago
> Can one use UTF8? For new standards, yes. But ASN.1 was first specified in the '80s, and backwards compatibility is a thing. So really it depends on what you're doing: if you can start with a subset of ASN.1, which I think

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