mcbain

8 ms·

31.
by mcbain 3y ago
> That wasn't my experience Then stop talking like you understand cancer treatment or clinical trials, because it is exactly how it works for thousands of people every year. > Too bad Pardon me? "Too bad" that I had rec
32.
by mcbain 3y ago
No, immuno isn't always a second line treatment. No you don't need to have failed other treatments before being added to a clinical trial. Quite the opposite in many cases - they have entry criteria so that they can be sure any ef
33.
by mcbain 3y ago
There is no "most effective" treatment because cancer isn't one thing. Chemo is effective for a few cancers but not for others. Immuno might be the most effective for those. Or chemo followed by immuno. Maybe it is CRT (chemo
34.
by mcbain 3y ago
If it doesn't come out beforehand it'll likely be presented at ASCO: https://x.com/profglongmia/status/1753650640847597930
35.
by mcbain 3y ago
I'm not sure if they've said publicly what immunotherapy they used. I have seen it referred to as a combo, so I would guess ipi/nivo - that is Nivolumab (Opdivo) + Ipilimumab (Yervoy). They've been trialling those as ne
36.
by mcbain 3y ago
I don't always love the video format but Mentour talked about Spirit, Boeing, and the 737 MAX a few months ago: https://youtu.be/SmJgweFmoxs The discussion about snowman hole issues and other problems is really alarmin
37.
by mcbain 3y ago
Which is also the OP's (BurntSushi) work.
38.
by mcbain 3y ago
A friend's child was given one of these, and I'm envious. Not only is it a cool model but I also have to get regular MRI - I've got another one today in fact. Having the model has really helped with their anxiety and means we
39.
by mcbain 3y ago
Some context is that Profs Scolyer and Long have recently had a lot of success with immunotherapy for melanoma used as a neo-adjuvant - that is, before surgery. Start the patient on immuno asap and then excise so the immune system is trigge
40.
by mcbain 3y ago
https://www.smh.com.au/national/nsw/five-cars-destroyed-at-s... “There had been some problem with the car and the battery had been removed, we believe that the car has suffered some mechanical damage which can con
41.
by mcbain 3y ago
Three. Two operated by other companies (in Beijing and Ningxia) that are only available in China, and Hong Kong which appears to be just another AWS region available globally.
42.
by mcbain 3y ago
There are many papers - development of immunotherapy for melanoma has been a big topic for the last few years, with some fantastic improvements but more to do. As it happens I can spot that the linked paper is already out of date as I know
43.
by mcbain 3y ago
Google CloudSQL Enterprise vs Google CloudSQL Enterprise Plus.
44.
by mcbain 3y ago
The painful part is that if you at or near the top of the previous band it often means not a significant bump at promo time. The top of the new band is much higher of course, but there isn't as much immediate payoff.
45.
by mcbain 3y ago
Maybe there are some efficiencies to be found, but we are talking about experimental treatments where the efficacy takes weeks to years to measure. You can't run an overnight benchmarking test. But in saying that, if a trial is showing
46.
by mcbain 3y ago
The rule of thumb is that it takes 4 weeks for a concrete driveway to fully cure. I admit I've never built a launchpad for the world's biggest rocket, but I'd wave my hands to say it might take a bit longer for that concrete,
47.
by mcbain 3y ago
Or shell, or ruby, or markdown, or even just use Slack. Sure there are generally (sometimes better) alternatives in those but backticks are pretty common for me.
48.
About the security content of iOS 16.3.1 and iPadOS 16.3.1(support.apple.com)
3 points by mcbain 4y ago|1 comments
49.
by mcbain 4y ago
The same is true for some of the more vocal accounts here on HN, as elsewhere. I don't keep a list of usernames but a few folks talk with authority across a range of topics - both tech and adjacent interests - and when they happen to s
50.
by mcbain 4y ago
We've even got children's propaganda for these birds!: https://www.amazon.com.au/dp/1743830041
51.
by mcbain 4y ago
I love magpies. Clever birds, iconic look, and beautiful songs, but they are super aggressive territorial bastards for a month or so a year. Yes, I've been violently harassed by them while waking and riding bicycles through "their
52.
by mcbain 4y ago
Immunotherapy is also being trialled as a neoadjuvant with promising results.
53.
by mcbain 4y ago
There's not one answer but often: yes, split into "arms" receiving SoC or trial. Details on this is part of the trial listing which is usually on https://clinicaltrials.gov/
54.
by mcbain 4y ago
The field is known as anaplastology and while the article throws shade on the movie industry, there are some talented people that have come across from there.
55.
by mcbain 4y ago
When cryptocoin folks try to reinvent the Fyre Festival.
56.
Satoshi Island Project(abc.net.au)
2 points by mcbain 4y ago|4 comments
57.
by mcbain 4y ago
Of course it varies by cancer. Look up "adjuvant immunotherapy". It is now standard of care for melanoma, for one, but it isn't successful for all cancers, (or even all melanoma mutations).
58.
Notice of a Data Security Incident(mysupport.shangri-la.com)
1 points by mcbain 4y ago|0 comments
59.
by mcbain 4y ago
I don't think it has been a single EBS volume for a while, but in any case, 256k is more than 18k. https://docs.aws.amazon.com/AmazonRDS/latest/UserGuide/CHAP_...
60.
by mcbain 4y ago
Regarding blinding: I was part of a clinical trial (phase III, not the drug or cancer this article relates to). It couldn't be blinded - the side effects of the trial drug were too significant compared to just the standard of care whic

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