mbreese

33 ms·

721.
by mbreese 3y ago
Is it just me, or are the pin numberings (not the order) wrong on their 568A/B pinouts? I’m having a hard time getting past that…
722.
by mbreese 3y ago
Somewhat ironically, you mentioned the Google results were unhelpful. But, the DDG results for this search look pretty reasonable. https://duckduckgo.com/?q=add+duck+duck+go+to+default+search... The first hit: https:/
723.
by mbreese 3y ago
> basically subsidizing the extremely popular artists I don’t think this is right. I don’t know much about revenue distribution, but I think you’re conflating listeners and money. The ratio between the two is not constant. And I think
724.
by mbreese 3y ago
Yeah, I can’t think of a reason why I’d really want to hand edit a CSV file. I think the rationale behind using CSV is even more basic. The reason why CSV is so popular (and TSV, HTML and JSON for that matter), is that it is a human readab
725.
by mbreese 3y ago
Look, you obviously have your opinions here. I'm not sure just saying "Complete nonsense" at things is really all that helpful. What I said ( "it doesn't tell you anything about the ability to differentiate between
726.
by mbreese 3y ago
This is an unbalanced study. As such, it doesn't tell you anything about the ability to differentiate between the three populations. You can argue about the terms "negative control" (which is appropriate here, as there is a p
727.
by mbreese 3y ago
With so few controls, it’s still not a well designed comparison. Most scientists deal with low sample sizes, especially in first trials. However, what is often overlooked is the need for sufficient numbers of negative controls. If they only
728.
by mbreese 3y ago
> Proteins (for example Glial Fibrillary acidic protein, GFAP) had previously been identified as potential biomarkers for dementia in smaller studies, but this new research was much larger and conducted over several years. The article
729.
by mbreese 3y ago
Anything “clever” in a legal sense is a red flag for me… Computer people tend to think of the law as a black and white set of rules, but it is and it isn’t. It’s interpreted by people and “one clever trick” doesn’t sound like something I’d
730.
by mbreese 3y ago
That dovetails nicely with the trends in cameras. When Flickr first started, all of the most popular cameras were DLSRs. Cameraphones were around, but not as common (and Nokia is on that list!). However, as soon as smart phones (iPhones) be
731.
by mbreese 3y ago
But that’s the point of standardization. You are trying to ensure that the core functionality works for everyone regardless of who the vendor is. A mobile network much more akin to SMTP/IMAP than it is to intra office calendaring (but
732.
by mbreese 3y ago
Strong, yes. It’s certainly possible to have binding sites that prefer larger molecules. However, I’m not sure you’d be able to do so while still being able to function as a polymerase. That’s the thing I’m thinking about. You have to have
733.
by mbreese 3y ago
Right? The unlabeled nucleotide will still fit in a binding pocket for the labeled version. And it should always have better binding. But this is an obvious issue. With this type of photo-reaction, you’ll get a build up of unlabeled nucleot
734.
by mbreese 3y ago
$200k might be enough to generate a few candidate designs (in silico), but still probably not enough to actually test/validate them.
735.
by mbreese 3y ago
The lack of a validation protocol is also an issue for the another way for doing this — generationally mutate the polymerase and let evolution do the work for you. But, this only really works when you have an automated test to know which va
736.
by mbreese 3y ago
Intellectually though, I could see the WinFS failure as being more disappointing. If it had worked, local computing would have been completely different. Much like BeFS, WinFS (as marketed) would have introduced many new ways to interact wi
737.
by mbreese 3y ago
Does anyone know how well the Seaweed Filer works for renaming files or missing files? My use case’s involves writing a lot of data to temporary files that are then renamed to their final name. This is always the Achilles heel for distribut
738.
by mbreese 3y ago
My only point is that the initial iPhone was an expensive phone that didn’t have typical carrier subsidies. It was successful in spite of this. The original parent post claimed that it did and implied that this was the reason why it was so
739.
by mbreese 3y ago
The contract was a requirement, but it wasn’t subsidized like you’re thinking. Other phones at the time were cheap and subsidized as part of the contract. The iPhone, by comparison, was freakishly expensive and I don’t think Cingular was su
740.
by mbreese 3y ago
> Want it for entertainment? people want to enjoy photos, videos, movies with other people and it can't include them This is a disingenuous argument. Your other points are much more valid than this one. You don’t have a VR headset
741.
by mbreese 3y ago
I had phones before the iPhone that took pictures and played music (and a Nokia tablet with wifi internet browsing). The iPhone was the first one that I actually used to take pictures and play music. It wasn’t the first to have those featur
742.
by mbreese 3y ago
The original iPhone wasn’t subsidized… it was bought outright. It was only after Apple proved the potential of the iPhone did the carriers get on board (and even then, it was limited support for quite a while).
743.
by mbreese 3y ago
Right, but you need to be at a particularly high scale when you need to write code that directly interacts with a cloud provider. I can think of no use case where you are at that level that can also scale down to a home lab setup. Yes, you
744.
by mbreese 3y ago
> This isn’t to be polite or to make money — it’s to foster adoption among developers, which drives sales. I get that in theory… and it makes sense most of the time. I’m not sure it does this time though. You don’t exactly “target” Oxi
745.
by mbreese 3y ago
At the time, Fortnite and Minecraft (and more) were my son’s way to socialize with friends. That was how they hung out (pre Covid). I can honestly say it would have been detrimental to him from a mental health perspective if those outlets d
746.
by mbreese 3y ago
What are the features you’d say are required for “professional” use? I can think of a few things that I’d like to see, such as better keyboard navigation and the return of a spatial finder. But I think that if you asked ten people that ques
747.
by mbreese 3y ago
Another place to look for inspiration is the HPC world. Fairshare job queues have been active on multi tenant HPC clusters for decades. Each job typically has a priority value assigned to it based on the submission time, expected resources
748.
by mbreese 3y ago
Yeah, I can’t see how use of a —-force flag by people who didn’t know what they were doing is enough of a reason to switch to a different VCS (let alone write one). The issue was people using a tool in a way that they shouldn’t have. Which
749.
SeaweedFS is a simple and highly scalable distributed file system(seaweedfs.github.io)
3 points by mbreese 3y ago|0 comments
750.
by mbreese 3y ago
> Maps from 2005 was a very sleek product, but at the time there were no competitors on the web Mapquest would beg to differ. To me, the interface was the killer feature for Maps. The data and trip planning functionality existed alread

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