markkat

8 ms·

91.
by markkat 9y ago
1. There may be few pluripotent cells in what we collect, but the majority of stem cells collected are multipotent (mesenchymal and hematopoietic lineages). 2. We haven't been cryopreserving stem cells for 60 years, so that is impossib
92.
by markkat 9y ago
It is legal to store them. If you want to expand (grow them to greater numbers) AND use them therapeutically, then you must be part of a clinical trial in the US. Many clinical trials using these cells expand them. I have grown some of my o
93.
by markkat 9y ago
The cell populations are actually quite similar; there are both mesenchymal and hematopoietic stem cells in cord blood and bone marrow. In many ways, our service is 'cord blood banking for adults'. However, unlike a cord blood ban
94.
by markkat 9y ago
Currently, we only perform collections in the US. We do have clients from other countries that have banked with us. Our biorepository is in MA. Once you've banked with us, we can arrange to have your cells sent anywhere, however.
95.
by markkat 9y ago
There are mesenchymal stem cells (MSCs) in dental pulp. I have not studied them myself; however, they are reportedly similar to bone marrow MSCs. We bank all the nucleated cells in the bone marrow for two reasons: 1) there are high numbers
96.
by markkat 9y ago
Not something we provide! :)
97.
by markkat 9y ago
Thanks! Here's a small collection of research: https://foreverlabs.com/blogs/research Also, here are some recent clinical trials using autologous bone marrow for treatment of heart disease or stroke: https:/
98.
by markkat 9y ago
We currently have enough clients that the annual storage fees paid in more than cover the costs of our repository. We are actively pursuing two options to address this possibility: 1) The cell banking service is a separate entity, and all o
99.
by markkat 9y ago
The decline in functionality begins to be detectable between 20-40, and accelerates with age. This study has a number of measures regarding bone mesenchymal stem cells (which are included in what we collect and store): https://ww
100.
Launch HN: Forever Labs (YC S17) – Stem-Cell Banking
83 points by markkat 9y ago|69 comments
101.
by markkat 9y ago
We store the cells in three larger aliquots and six smaller ones. Most clinical applications employ prior expansion of the cells before administration. As an example, this trial using them to aid in kidney transplantation uses 1-2M mesenchy
102.
by markkat 9y ago
(Mark from FL) >Banking cells for the purpose of use later in regenerative medicine is supremely pointless. It is a hedge against technological development in cell reprogramming and repair Obviously, I disagree that the hedge is pointles
103.
by markkat 9y ago
Hey, Mark from FL, here. For bone marrow mononuclear cells or mesenchymal stem cells, the closest are phase III, such as for heart attack https://clinicaltrials.gov/ct2/show/NCT01569178 and stroke https:/&#x
104.
by markkat 9y ago
Great additions! Gustaf is very insightful.
105.
by markkat 9y ago
From what I understand, Ambrosia is transfusing plasma, not whole blood. There are a number of studies, going back many years, suggesting that young blood has a rejuvenating effect in older animals. I have been using bone marrow mesenchymal
106.
by markkat 9y ago
We at https://hubski.com use a very hacked version of news.arc. Going on seven years. We moved data to postgres though. The app is top notch, but it does not scale very nicely. Too much to hold in memory.
107.
by markkat 9y ago
That's fascinating. I started a company that cryopreserves adult stem cells. Would you mind sharing what kinds of datasets you are mining? Here or email (in my bio).
108.
by markkat 9y ago
What worries me most, and why I stopped Soylent, is that the quality is not in their hands, but in the hands of their suppliers. Do they test everything that they receive to confirm that it is what the supplier says it is?
109.
by markkat 10y ago
Agreement by that definition is not a necessary condition, only a possible scenario. Majority hashpower is the built in way of handling disputes.
110.
by markkat 10y ago
It's not an attack if the majority of miners decide to use a specific implementation. That's how bitcoin works.
111.
by markkat 10y ago
IMO they will both continue to grow. Bitcoin simply cannot do what Ethereum can, and as a result, Ethereum will continue to be used.
112.
Risky therapy using chemo and autologous stem cell transplant stops MS for years(bbc.com)
3 points by markkat 10y ago|0 comments
113.
by markkat 10y ago
What is your IF schedule?
114.
by markkat 10y ago
>Is that something you can request from your physician? In MI, NC, and CA atm. Full disclosure, I co-founded the company: https://www.foreverlabs.co/ . >Is it the same process as donating marrow? Like an aspiration, bu
115.
by markkat 10y ago
This is a personal anecdote, but I went through about 10 years where I was getting colds and flu-like symptoms several times each year. I did a 72hr fast almost three years ago now, and have only been stay-home sick once since, which happen
116.
Peter Diamandis: Stem Cell Revolution(diamandis.com)
1 points by markkat 10y ago|0 comments
117.
by markkat 10y ago
Wow. No notice at all? That's terrible. I just transferred out my BTC. Deleting the app.
118.
by markkat 10y ago
The article didn't mention tokenization of shares and token-based fund-raising. Presently, that is a far more disruptive and interesting use case for blockchains.
119.
by markkat 10y ago
Yes, I started my own company. Doing something that I have wanted to for a while.
120.
by markkat 10y ago
I've been in biomedical research for 15 years, and I am leaving the lab atm. Many of my peers are as well. It's not a viable or enjoyable career anymore. Funding is extremely political, and proposal reviews border on arbitrary. Ty

More ›