loeg

26 ms·

781.
by loeg 9mo ago
It doesn't quantify winter range. It gestures at possible benefit; without comparison to the state of the art, it's not especially meaningful. Nevermind that losing less than 10% of 250 miles is not a ton of range.
782.
by loeg 9mo ago
I don't think 2x slower is plural "orders of magnitude" no matter how you count it. It's at best a single power of two.
783.
by loeg 9mo ago
> and you have a garage charger or some other easy access to a charge station. I wouldn't recommend EVs in any climate without home charging.
784.
by loeg 9mo ago
Huh. It's hard to tell how legit any of these "compounding pharmacies" are, but some example letters: https://www.fda.gov/inspections-compliance-enforcement-and-c... https://www.fda.gov/inspe
785.
by loeg 9mo ago
That has nothing to do with drug development expense, which is what you claimed originally.
786.
by loeg 9mo ago
In this metaphor, the car manufacturer only invested R&D in new models because it expected to be able to recoup that R&D spending from my higher purchase price. If I start paying the same low price for cars as you do, the manufactu
787.
by loeg 9mo ago
On par on a per kg basis, but is it on par on a volume basis? If it takes up more space, that might pose packaging challenges relative to LFP.
788.
by loeg 9mo ago
Cold weather performance with heat pumps and lithium batteries is fine. Don't worry about it. I wouldn't try to hold my breath until a US automaker produces a sodium battery EV.
789.
by loeg 9mo ago
Nothing in the article really substantiates the headline (currently "The First Sodium-Ion Battery EV IS a Winter Range Monster"). The EV described in the article has a standardized range of 250 miles. This isn't a range mons
790.
by loeg 9mo ago
These are international companies that depend heavily on profits from the American market. Their C suite knows this; their investors know this.
791.
by loeg 9mo ago
Yes, bootleggers can undercut legit competitors, providing a boon for consumers. In this case, Novo developed the drug. In your view, why does Hims get credit for "the greatest good to public health in a century" and not the co
792.
by loeg 9mo ago
> because the FDA makes it that way with their paranoid risk averse regulatory process FDA is constrained by Congress here. Its function (safety and efficacy in advance of marketing) is required by legislation dating to the 60s. Feel f
793.
by loeg 9mo ago
> There has also been cases of compounding pharmacies offering reta and other unapproved peptides Can you elaborate more on this? I hadn't heard about it.
794.
by loeg 9mo ago
I'm not taking a side here.
795.
by loeg 9mo ago
> I would've had to pay close to $1k a month to take it otherwise. If your frame of reference for GLP-1 prices is in like, 2024 or earlier, check prices again. They've come down a lot. You can get tirzepatide from Lilly witho
796.
by loeg 9mo ago
And 3) US consumers pay less for pharmaceuticals. Together this might be a net positive for US consumers (even if they get fewer new drugs out of the bargain).
797.
by loeg 9mo ago
No, they're free-riding. If drug companies can't charge higher prices in the US, they will do less drug development. Everyone involved in the business/investing side of pharma knows this; it's not even an argument.
798.
by loeg 9mo ago
This article doesn't mention Russia at all.
799.
by loeg 9mo ago
The regulation is pretty clear? We just don't choose to blackhole shady foreign (in this case, Chinese) companies from the American internet as a matter of policy. And cannot effectively screen all imports.
800.
by loeg 9mo ago
Why is it bad when companies break the law? We have patent laws for a reason (to incentivize enormously expensive drug development). Novo and Lilly already sell direct to the consumer! Yes, you need a prescription, but once you have one y
801.
by loeg 9mo ago
I think this is compounding pharmacies selling legit semaglutide (or tirzepatide?), but doing the packaging (dilution in water) themselves. No? I don't think Hims is selling RCs. They're violating Novo's (or Lilly's) p
802.
by loeg 9mo ago
Presumably this shift happened due to another F word -- Fraud.
803.
by loeg 9mo ago
It is expensive in those other places for similar reasons as SF -- the government either tells them they can't (through zoning), or makes it very expensive (through regulation, like IZ / "affordable" housing), or limit p
804.
by loeg 9mo ago
> Good luck finding an electrician My local (urban) residential electricians aren't even busy -- they are booking less than a week out. By contrast, just last year they were booking six weeks out. The fall in EV infrastructure dem
805.
by loeg 9mo ago
This comment seems entirely tangential to the article.
806.
by loeg 9mo ago
> Using a phone when driving is completely legal, as long as it is hands free. This is not universally true, and as a matter of policy, it should not be true -- making phone calls while driving is distracting, whether you are holding the
807.
by loeg 9mo ago
Washington state is pursuing a similar law at a similar time. Presumably pushed by the same advocacy organization, whichever one it is. The Washington one seems impossible to actually comply with -- how the hell is the computer in a CNC m
808.
by loeg 9mo ago
I think you're missing the point. Without a market-coordinating motivation (i.e., legislation), any company that adopted a more expensive anti-knock would be competed out of the market.
809.
by loeg 9mo ago
Except, you know, NEPA.
810.
by loeg 9mo ago
Put more broadly, we should, you know, enact good laws and repeal bad ones. No major political party has a monopoly on good, or bad, legislation.

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