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kraussvonespy
searching PlanetScale…
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31.
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kraussvonespy
2y ago
Feels like this well written piece by Atol Gawande is relevant if you haven't seen it. I showed it a couple of years ago to my very competent and conscientious doc and she got PISSED. She talked about how she spent literally half of he
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kraussvonespy
2y ago
If it helps, here’s info from Dr. Derek Lowe, a 30+ year pharma chemist and author of In The Pipeline. For further research on the topic, he has many other posts on the topic, some of which are linked in the links below. https://
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kraussvonespy
2y ago
“But once you're already experiencing symptoms, there are other problem which clearing out the amyloid alone won't stop.” Ok, maybe we’re just arguing different points here. I’ll grant that amyloids have something to do with all o
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kraussvonespy
2y ago
Those quoting the 30% figure may want to research where that figure comes from and what it actually means: “Derek Lowe has worked on drug discovery for over three decades, including on candidate treatments for Alzheimer’s. He writes Science
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kraussvonespy
2y ago
Yes but only if you stay a private company. Once you issue stock, those like-minded individuals are going to be pressured to enshitify to maximize shareholder value. Or pressure the like minded to get acquired by a big pile of enshitificat
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kraussvonespy
2y ago
Which is bad too because if you turn your hobby into your career, you end up not having a hobby anymore. In order to have a happy life, you have to have a vocation and an avocation that are separate from each other.
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kraussvonespy
2y ago
And in the US, bankruptcy doesn't help with the student debt, so if the majority of your debt is student loans, there's really nothing that can be done other than die to get rid of them. And I'm 100% certain that if the stude
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kraussvonespy
2y ago
What that arngren.net is missing is the cheesy Johnson Smith ads for X-ray specs! and Sea Monkeys! Johnson Smith was like the cheap claw machine of magazine ads. You knew that all you were going to get was crap, but it was fun crap. Maybe i
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kraussvonespy
2y ago
I'm by no means an expert but I've seen some of what's being used to train AI, and I have to wonder if the hallucinations aren't coming from collisions of errors that got introduced while training. For example, if you do
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kraussvonespy
3y ago
How dare you besmirch the reputation of The Awesome Store! https://theamazingworldofgumball.fandom.com/wiki/Awesome_Sto...
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kraussvonespy
3y ago
100% agreed. The current system of "Sorry you feel suicidal / horribly depressed. Here are some meds that are statistically unlikely to help you but you won't know whether they help or not until ~60 days after you start takin
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kraussvonespy
3y ago
You're right. It looks like there are studies that indicate that dopamine is also increased by nicotine. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2946180/ Edit: er, sorry, you were probably talking a
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kraussvonespy
3y ago
Nicotine has antidepressive effects through increasing bioavailability of serotonin. It also shines as an antipsychotic. I’m failing to find the study right off but something like 80-90% of schizophrenics are smokers. Buspar works in smokin
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kraussvonespy
3y ago
McPhee is truly a national treasure. If you're interested, that article was one of several published in his book Uncommon Carriers which includes a train and river barge voyage. Looking for a Ship is also great as it follows a merchant
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kraussvonespy
3y ago
I'm not a chemist so this may be a dumb question, but is it possible that polymorphs are coming into play here, and the less official labs are better at contaminating the sample with the correct polymorph?
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kraussvonespy
3y ago
I feel like you might have missed my last paragraph. TL;DR: Traditional college maybe made sense before college debt became an albatross around college grad's necks. Time to find more reasonable alternatives for those that don't w
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kraussvonespy
3y ago
I've argued before that the "useless majors and departments" are useful for general studies, and general studies are good for everyone. Filler prereqs are a part of all of the college concept of creating a well rounded indivi
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kraussvonespy
3y ago
Could the material need to be "seeded" by the proper polymorph? https://en.wikipedia.org/wiki/Disappearing_polymorphs
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kraussvonespy
3y ago
After reading this article, it kind of feels like CF is a modern version of Howard Johnson's. Big menu, lots of dessert, more of the food is cooked in house, safe place for picky eaters. It may suffer the same fate as Hojo too in that
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kraussvonespy
3y ago
I recommended the Why Doctors Hate Their Computers to my GP doc. The next time I saw her and asked her about it, she was PISSED. She said she spends about as much time working on EMR info as she does seeing patients, and it really irritated
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kraussvonespy
3y ago
Political books are a different animal than other books. You'll find political donors buying a huge number of copies to propel the book to the top of the charts to make a political statement. (my ideas can't be crazy if 50K people
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kraussvonespy
3y ago
n=1 and all but ketamine is the only med out of 30+ that I've tried for my TRD over the last 40+ years that actually helped me long term. Every other med either had side effects that were worse than being depressed or they just didn&#x
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kraussvonespy
3y ago
James Pavur has some interesting papers on various types of satellite hacking, from using ML to determine that some "space debris" might actually be hidden spacecraft [0] to VSAT security [1] to Cyber Antisatellite weapons [2], an
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kraussvonespy
3y ago
https://xkcd.com/2259/ I found that one just after spending all day chasing an odd WAN issue for a customer. A few years ago in the era of half/full duplex in ethernet, duplex mismatches sometimes manifested in so
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kraussvonespy
4y ago
This would interest me as an employer of tech people. Interest in topics like ML/AI or quantum computing or crypto algorithms or reverse engineering all show that you're capable of figuring out complex technical issues without hel
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kraussvonespy
4y ago
That's something I should ask myself too when re-reading it. It has elements of: scientific heroism, science and technology ethics, the hacker mentality, and "science the shit out of it". The characters are quirky and interes
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kraussvonespy
4y ago
The article mentioned the book The Eudaemonic Pie by Thomas Bass. This was recommended to me back in the late 80s by my favorite professor in undergrad. It is quite good, a rare book that I go back and read every year or two.
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kraussvonespy
4y ago
I'm finding the same with other products too. There are a bunch of Aldi generic foods (like Mac & Cheese, tortillas, salsa, corn chips) that I like the taste of better than the more expensive name brand. Does this mean that the bra
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kraussvonespy
4y ago
Maybe just another derivative of the turnover or pocket pie? Empanadas, pasties, calzones, bierocks/Runzas, samosas all fall into the turnover category. Alton Brown's Good Eats had at least one show on turnovers and some of the di
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kraussvonespy
4y ago
Agreed. culitho wasn't an English word until nVidia marketing extruded it into the world. In my defense, I was trying to vaguely reference the Problem with Popplers episode of Futurama but failed.
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