jyounker

6 ms·

61.
by jyounker 4mo ago
First thing to remember: cancer drugs attack human cells. Because of this they can very unexpected and traumatic side-effects. Because of this initial trials consume lots of medical staff to deal with the potential side effects. Normal side
62.
by jyounker 4mo ago
Cancer treatments are really scary things. There are all sorts of impacts that we have no idea about when using drugs that fundamentally attack pieces of our own body. My partner of many years had one of the nastiest cancers around, one w
63.
by jyounker 4mo ago
And how is that different from any other governmental level? Seriously, we in Berlin got a freeway that nobody I know wanted or wants. It's not the EU's fault.
64.
by jyounker 4mo ago
So we're in agreement. The expectation is that biochemistry here on Earth only produces a small proportion of the possible structures.
65.
by jyounker 5mo ago
> What you have to be careful about here is that the structure that were available 30 years ago were quite strongly biased by what was experimentally tractable.... ie the recurrence of the same folds is in part related to what crystallis
66.
by jyounker 5mo ago
Fossil fuel companies have spent the the last forty years in an organized campaign to prevent the US (and by extension, the world) from taking action against global warming. There's a great book on the subject called "Merchants of
67.
by jyounker 5mo ago
I wasn't replying to the OP.
68.
by jyounker 5mo ago
> So what are the lessons here? The only lesson is that, to a biochemist, the result is not surprising.
69.
by jyounker 5mo ago
Exactly.
70.
by jyounker 5mo ago
I have a 30 year old book on protein structure on my shelf. One of the primary themes is the recurrence of the same structural motifs in proteins. The fact that biologic proteins use the same patterns for different functions isn't new
71.
by jyounker 5mo ago
> What do you mean by "reaction center" An enzymatic reaction center is also known as an "active size". It's the location within an enzyme's 3D structure where catalysis happens.
72.
by jyounker 5mo ago
"But global warming is a hoax. And even if it wasn't it's not our fault. People couldn't be the cause. And even if it is our fault there's nothing we could do about it." We have broken our world for the greed o
73.
by jyounker 5mo ago
None of this seems particularly surprising to someone who was an undergraduate level of biochemistry knowledge. Thirty years ago the professor in my Proteins class made a few relevant important points in his lectures: 1) Only handful of am
74.
by jyounker 5mo ago
From an algebraic standpoint, the answer is clearly f(x) -> [0, 255]. If you don't have f(n * 0) == n * f(0), then all sorts of weird stuff happens. Compare these two: For f(x) -> [0, 255] then f(0) + f(0) + f(0) = 3 * 0 = 0
75.
by jyounker 5mo ago
From an algebraic standpoint, the answer is clearly f(x) -> [0, 255]. If you don't have f(n * 0) == n * f(0), then all sorts of weird stuff happens, like: For f(x) -> [0, 255] then f(0) + f(0) + f(0) = 0 + 0 + 0 = 0 = f(0) For f(
76.
by jyounker 5mo ago
The answer is actually really easy, and it's been implemented successfully before: selective import taxes. You set import taxes so that they offset price advantages. If a country has shitty environmental laws, crappy labor protections,
77.
Jumping Spiders Seem to Dream(pnas.org)
7 points by jyounker 5mo ago|0 comments
78.
by jyounker 5mo ago
> Being asleep may trigger the things we need to get done, but that doesn't mean sleep is fundamentally necessary for the things we need to get done. It could be just that it happens to be the way our biochemistry is wired, and we
79.
by jyounker 5mo ago
The problem with outsourcing, as opposed to remote developers, is that it takes a really good manager and tech lead to make it work. My experience is that you have to write extremely detailed design documents and work specifications in or
80.
by jyounker 5mo ago
Prompting is just writing specification documents. A lot of people are very bad at this. I suppose that more to the point, a lot of people are just bad at writing.
81.
by jyounker 5mo ago
Weights are write-once data.
82.
by jyounker 5mo ago
Imagine how often this situation lie this would be happening without institutions like OSHA or the EPA. Stuff like this happens in Texas on a fairly regular basis, but it rarely ever makes national news.
83.
by jyounker 5mo ago
The poster was pointing out the irony that the town's residents support pro-water pollution policies at the national level. [Given that Henderson county went for Trump by 30 points, the probably also support pro-pollution policies at
84.
by jyounker 5mo ago
Well said.
85.
by jyounker 5mo ago
Since at least the 70s everyone knew that it caused lung cancer. It's just that industry spending prevented anyone from doing something about it, in the exactly the same way that we've been seeing with global warming.
86.
by jyounker 5mo ago
By "non-workable" I think people mean that it won't compile Hello World.
87.
by jyounker 6mo ago
I think you have a misperception of the past. The actors that played the great chinese detective Charlie Chan were Warner Oland, Sidney Toler, and Roland Winters.
88.
Mommy, Are the Inspirational Stories on LinkedIn Real?(mcsweeneys.net)
40 points by jyounker 6mo ago|0 comments
89.
by jyounker 6mo ago
It's not like there is one chemical plant. The plants start on the east side of town, and they pretty much go all the way to Beaumont. The night-time view Eastward from the top of the ship channel bridge is best described as "He
90.
by jyounker 6mo ago
I didn't really see anything smarmy about it. It seems to me that the reply was way off kilter.

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