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jryb
searching PlanetScale…
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151.
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Ask HN: Has the iPhone swipe keyboard gotten substantially worse lately?
2 points
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jryb
3y ago
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0 comments
152.
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jryb
4y ago
Anecdotally, I was toying around with Haskell around 2015 but concluded that while learning it deeply would teach me important lessons about software, I was likely never going to use it for work, and so I just dedicated myself fully to lear
153.
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jryb
4y ago
I don't understand any of this at all. I got the cheap 2700K LED bulbs from a big box store (~$3 for a pack/bulb, I don't remember) and they are wonderful, they're just as good as they were when I got them, and the spect
154.
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jryb
4y ago
Nature is already doing this experiment, right now, and has been for billions of years. This couldn't cause problems even if we wanted it to.
155.
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jryb
4y ago
For some applications, yes, but it comes at the cost of not knowing how powerful ChatGPT really is. So the claim from OpenAI that ChatGPT 4 can pass the bar exam are deceptive since it will likely fail any future bar exam.
156.
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jryb
4y ago
I would prefer to keep this information in version control. A commit message with a thorough explanation of why the previous version failed and how the change resolves the problem would accomplish the same thing as a comment in the code, bu
157.
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How Scientists Are Using AI to Talk to Animals
(scientificamerican.com)
3 points
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jryb
4y ago
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1 comments
158.
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jryb
4y ago
I don't have it on my phone but I recently got a home 5g modem and it's excellent - speed and latency are both good and indistinguishable from my old cable internet service. If nothing else, I welcome it as a long-overdue competit
159.
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jryb
4y ago
This has also been seen before. Type III target binding results in the activation of non-specific nucleases. Cas13 non-specifically degrades ssRNA after target binding. Cas12a target binding results in non-specific ssDNA cleavage, though it
160.
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jryb
4y ago
Clickbait-y title - this sort of thing has been seen before - it's just that this protein is more flexible about what kind of nucleic acid it will degrade. Definitely interesting but not revolutionary.
161.
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jryb
4y ago
FWIW, I don't believe I've ever heard anyone talking about it, positively or negatively, in real life.
162.
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jryb
4y ago
I think it would be better to say that it's random-inspired - you get a riff or a piece of a melody, but the whole song still has some artist-imposed structure or else it would be unlistenable. There's some nuance that I feel is w
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Property-Based Testing in Rust with Arbitrary
(greyblake.com)
89 points
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jryb
4y ago
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23 comments
164.
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jryb
4y ago
> The exact circumstances of Z-Library’s shutdown are still unclear. Some of its many domain names simply won’t load. Others lead to a message reading: “This domain has been seized by the United States Postal Inspection Service in accord
165.
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jryb
4y ago
I put Xubuntu with i3wm on mine, and it works without issue.
166.
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jryb
4y ago
Honestly it sounds like you should stick with Rust a while longer, until those low level things no longer present an obstacle. I've finally gone all-in on Rust and after a few months of full-time use at work I feel like I've "
167.
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Rust 2024 the Year of Everywhere?
(smallcultfollowing.com)
102 points
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jryb
4y ago
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196 comments
168.
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What I meant by the “soul of Rust”
(smallcultfollowing.com)
5 points
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jryb
4y ago
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0 comments
169.
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jryb
4y ago
These tests are performed routinely. I can't find the reference but i believe it's every two weeks or so.
170.
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jryb
4y ago
I've always wondered why this kind of thing wasn't available much earlier. We've had electrolysis for a long time now - are fuel cells the limiting technology here? Are electrolyzers not as simple as I expect?
171.
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jryb
4y ago
These numbers seem suspiciously high. In the paper (from 2011), it estimated that laptops contain 871 grams of steel and 244 grams of epoxy, among other things (the total weight is 2kg more than a modern dell xps). The steel figure is from
172.
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jryb
4y ago
I do all my development on a remote server, so I really just need a terminal emulator and an internet connection. I could work with a raspberry pi if I needed to. Sure, fundamentally it's just moving the problem of where the expensive
173.
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jryb
4y ago
All mRNA is regularly degraded. Just because it gets translated doesn't mean it is immune to the degradation machinery. In any event, none of this even matters - the mRNA and spike proteins are completely innocuous on their own and thi
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jryb
4y ago
I've been doing the same thing and also have gotten no spam to the non-main address. That said, I don't get much spam at all. I recently decided to stop the practice.
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jryb
4y ago
It was indeed a huge amount of computation. On Colab it takes about 2-3 hours to fold a single protein. So the resources required to fold 200 million is far beyond what most organizations have. Just as importantly, making the results easy t
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AlphaFold predicts structure of almost every catalogued protein known to science
(embl.org)
2 points
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jryb
4y ago
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0 comments
177.
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jryb
4y ago
Almost definitely - they're using MGI sequencers, which can't be sold in the US or Europe due to patent infringement (until August 29th in the US). Some have been sold outside of China in Asia.
178.
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jryb
4y ago
It's super complicated - clinical trials of phage therapy have been relatively unsuccessful for one thing, so there's that. But additionally: - Bacteria adapt to phage infections, just as they do to antibiotics - Many phages
179.
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jryb
4y ago
There are plenty of people/companies working on phage therapies, and there are clinical trials happening now [1]. In some eastern European countries you can buy phage solutions over the counter. It just doesn't get much press - th
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jryb
4y ago
I eat only plant-based foods and actually prefer unique names/spellings for these products. It can be worrying when an ostensibly vegan restaurant sells something that really tastes like meat and the menu says "beef" or whate
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