jonlucc

9 ms·

151.
by jonlucc 8y ago
Not necessarily. Would you say that a museum or university isn't sustainable because its revenue from goods and services is less money than it spends? If they have an endowment or similar vehicle set up, they can use interest to pay sa
152.
by jonlucc 8y ago
It really depends on the specific animal, but common wisdom is that you can't just leave a bowl of food out for a dog. Cats on the other hand often are free-feeders (leave out a big bowl of food and refill it on a schedule). Of our 2 c
153.
by jonlucc 8y ago
The 991 GT3 is $140k?
154.
by jonlucc 8y ago
It's just about every way you could imagine. I work at a large company, where my department has something like 75 people in 25 labs working on one disease area. Anything we think we can build a case for is worth considering, and we&#x2
155.
by jonlucc 8y ago
There is some work in this direction that is based on work with human cells (preferably primary cells) and building an otherwise compelling case. You have to be incredibly careful to do the appropriate safety studies and find some way to sh
156.
by jonlucc 8y ago
I work in pre-clinical pharma research, and this isn't really true in my experience, but there are a couple caveats. At least in my experience, we wouldn't run the same study again, but we might change the model. There are a few m
157.
by jonlucc 8y ago
Why at the doctors specifically?
158.
by jonlucc 8y ago
Both T1D and T2D are increasing year-over-year. Also, 90-95% of diabetics in the US have T2D, so the 15% of T2D patients on insulin is still 13.5-14.25% of all diabetics. We already know that 76.5-80.75% of all diabetics aren't using i
159.
by jonlucc 8y ago
Anecdotally, I have a few locations I put in weekly or so to make sure I have an accurate ETA or to see if one of two routes is obstructed. They autocomplete as soon as I type the first letter of either, and they're in the dropdown lis
160.
by jonlucc 8y ago
If you have a chance, a few of these satellites are on display at the National Museum of the USAF in Dayton, OH. Last time I was there I took a few pictures of the KH-7, KH-8, and KH-9. https://imgur.com/gallery/P89GME7
161.
by jonlucc 8y ago
Lots of people have said this, but Facebook has upload directly from phones to their server, right? So I would be shocked if they aren't trusting the time tags from direct uploads and metadata set by the camera (which they strip before
162.
by jonlucc 8y ago
I could see that, but couldn't it give a lesser-known or less desirable VC an edge?
163.
by jonlucc 8y ago
I don't think so; there must be many other factors. You seem to be saying that people are more motivated by not being able to afford healthcare and college for themselves or their kids, and that seems bonkers to me. If that were the mo
164.
by jonlucc 8y ago
Maybe this is hopelessly naive or dumb legally difficult, but I wonder if a VC might have a slight advantage by offering funded companies a portion of the fund itself. They might be more enticing to founders. Of course there's still so
165.
by jonlucc 8y ago
Can I ask why? Is it because that company is profiting off of your data or something else?
166.
by jonlucc 8y ago
I'm not exactly an expert in this field, but I work in big pharma, and I've seen the presentation 23andMe gives to drug companies. Basically, there are two ways GSK can use your data stored at 23andMe, and both require explicit op
167.
by jonlucc 8y ago
Sure, you can hire the fish pathology expert (or send samples out to a lab), but our facility requires us to have "clean" fish coming in, so we can't do the exercise of breeding, treating, and certifying fish in our own facil
168.
by jonlucc 8y ago
You joke, but I work in a pharmaceutical company, and we have a program specifically for employees to donate blood for research purposes. It's complicated so that the donors and researchers are blinded to where the blood comes from and
169.
by jonlucc 8y ago
As the other comment mentions, the embryos are, but also, you can get amelanistic zebrafish. This might be an interesting addition. You can't usually just buy zebrafish from Petco and use them for research. There are standards in anima
170.
by jonlucc 8y ago
Some locations also offer eye exams, but it makes sense to me. This allows them to buy small storefronts. The one near me is something like 250 or 300 square feet with only 1 or 2 employees at a time.
171.
by jonlucc 8y ago
Which pays for a lot of marketing. That's not insignificant.
172.
by jonlucc 8y ago
> "national ID with a cryptographic token" means that OpenID / Paypal-based single-sign on logins are illegal. Why? Why doesn't it just mean that there's a canonical government system that doesn't touch PayP
173.
by jonlucc 8y ago
Even when I was a contractor, I never quite understood this. The contractor costs Google whatever it costs the contractor to employ them plus some amount of profit for the contract company. It would be cheaper to just employ people at a c
174.
by jonlucc 8y ago
Gladly! I'm in the US, so it may be a bit different, but here is my experience. To start, would I do it again? Yes, in a heartbeat. I was fresh out of undergraduate with a degree in biology, but very little experience in labs. I spent
175.
by jonlucc 8y ago
I think this is referring to something different, but I could be reading it incorrectly. I think this is essentially that Google has a contract with the companies named, and then the contractors are full-time, regular employees of the contr
176.
by jonlucc 8y ago
I work in pharma, and I was a contractor before I was hired on. It's a similar situation to what's described in the article, where contractors are full-time employees of a third-party company, and that company's rules are the
177.
by jonlucc 8y ago
I mean what you say in your edit. Even off-patent drugs require basic proof that they are what they claim to be, are similar to the patent drug in important ways, have a safe formulation, require a company to make a production line for it,
178.
by jonlucc 8y ago
And yet my mother is 100% convinced that the generic of a drug gives her chronic headaches while the "brand name" version doesn't. If I'm not mistaken, the formulation could be wildly different as long as they match kine
179.
by jonlucc 8y ago
That's true because it's not trivial to launch a new drug/delivery system. Even generics have to prove that their drug matches the kinetics of the patent drug and has other similar properties. There is still an FDA process to
180.
by jonlucc 8y ago
I may be totally wrong, but I think the point is that just about any company can grow 38% for a long time if you throw enough money at it. So far, lots of people have thrown lots of money at Uber, and some days it looks like they're no

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