jebus989

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How I Wrote an Ultra-Fast DNA Sequence Alignment Algorithm in JavaScript(medium.com)
106 points by jebus989 12y ago|52 comments
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by jebus989 12y ago
Even the original twitter blog seems to have gone out of its way to make this seem more complex then it is... Decomposition of time series is done with STL (stl function in stats package) and this is the first part of what they call "S
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by jebus989 12y ago
Unsure of how much editing you've done but I've made over 10,000 edits over the past 9 years and that's not been my experience (google my HN username + wikipedia).
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by jebus989 12y ago
Happy to continue to debate this point (possibly on another medium?) but no, a comment 437 days ago on HN saying "I once tried to edit but was reverted" is not evidence that too many rules have "murdered wikipedia", your
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by jebus989 12y ago
You're making leaps of logic based on the occasional HN anecdote. Numbers have been in decline since 2007, what percentage of those left over bickering about rules? Do you have any evidence for this given that IAR has been in place as
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by jebus989 12y ago
Sure editor numbers are in decline, that doesn't support your point. Ignore All Rules is one of the fundamental principles the site was founded on.
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by jebus989 12y ago
"Murdered" Wikipedia whose fifth pillar is "ignore all rules"?
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by jebus989 12y ago
In fairness the original "reporting" was for some buzzfeed-y 12 reasons to love New York, alongside "Because We Were All Taylor Swift Once" (which seems to be some tautology about being excited about NYC, not really sure
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by jebus989 12y ago
But asexual reproduction can also be known as cloning! Just a bad/unfortunate analogy.
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by jebus989 12y ago
Such as a 20x heightened risk of developing Alzheimer's relative to baseline (as determined by your ApoE variant).
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by jebus989 12y ago
That's their terminology I believe (hence quotes). However, for fun you can have a go at imputing a full genome from these SNPs (e.g. http://genomesunzipped.org/2013/03/learning-more-from-your-2... ). SNPs are
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by jebus989 12y ago
> It wouldn't take much for companies to start requiring that you disclose the knowledge you're at (high?) risk of something and adjusting their prices accordingly - particularly in long term policies. That's what insuranc
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by jebus989 12y ago
Of course, they're just calling SNPs and using published GWAS studies to estimate disease risk. You can get your "raw genome" text file from 23andMe and convert to e.g. VCF format for use in a bioinformatics tool like the var
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by jebus989 12y ago
> Wikipedia creates an enormous barrier to better information due to its size and scope, and its co-dependent relationship with Google. Too silly to address. > Wikipedia's medical information is unreliable and dangerous. Wikipedi
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by jebus989 12y ago
Ironically that comic and XKCD in general falls into the category of things that are very widely-known but people still present as new information. (The prime example being cryptography discussions linking to correct horse battery staple.)
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by jebus989 12y ago
Less roughly 38k GBP ~= 61k USD. It's been a good half-decade since it was two dollars to the pound.
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by jebus989 12y ago
The second part of your quote (which comes first) was previous research they were setting out to repeat, instead they conclude with "Results do not support the hypothesis that caffeine differentially affects extraverts and introverts&q
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by jebus989 12y ago
Well road testing starts January 2015 in the UK, and in Gothenburg from 2017 [0], presumably many other European countries have similar plans so we'll see! [0] http://www.bbc.co.uk/news/technology-28551069
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by jebus989 12y ago
I understand the confusion but this isn't Windows XP Home with MS Paint and pinball — it's XP embedded (XPe), a minimal OS tailored to specific hardward and still receives security updates until 2016-19 depending on version purcha
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by jebus989 12y ago
B is a indeed good idea and it already happens, though not as much as Wikipedia would like. Why make a class write a long essay that'll eventually be filed in a bin somewhere when they could be make real contributions to open knowledge
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by jebus989 12y ago
> Apple takes down another indie dev More factual title: "Launcher removed from App Store".
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by jebus989 12y ago
Context: this is a site claiming to create landing pages with said conversion rate in a day. Landing page itself was designed in a day. Additional context: > My landing pages convert at over 10%. Even as high as 17%.
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by jebus989 12y ago
I'd wager it doesn't have >10% conversion however...
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by jebus989 12y ago
As well they should. This one poll gives the appearance of a trend towards Yes and a dramatic close finish, but Yes have always been behind by a fairly consistent margin [0]. Just so happens the odd poll (~2/50 now) finds a Yes majorit
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by jebus989 12y ago
I'd say you're massively selling current knowledge short. Of course in biology you can always go a level deeper and say "but how exactly ... " however there's been a lot of research on mitochondria and there are en
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by jebus989 12y ago
Most uses of "gene" in this thread should be replaced by allele.
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by jebus989 12y ago
The mitochondria has a genome (mtDNA). Not my area but I think while we initially thought it was a fossil of the mito's prokaryotic history and we'd subsumed all the good stuff, there are genes there that may be of interest for ex
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by jebus989 12y ago
I'm not saying IS are the Donetsk separatists, just that they're not hiding in mountain ranges or tunnels and there's never been a question of "where are these guys".
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by jebus989 12y ago
I like this, but probably worth mentioning that this isn't a covert group so it seems somewhat akin to reporting where the Donetsk separatists are.
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by jebus989 12y ago
Absolutely right, Anders Ericsson has called Malcolm Gladwell out for misinterpreting his results for this exact reason. Not sure how widely available this is for playback but "More or Less" did a great podcast on this earlier thi

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