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jamessb
searching PlanetScale…
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391.
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jamessb
11y ago
'Nucleic acid circuits'/'DNA circuits' are conceptually entirely different to 'genetic circuits'. In the former, you design sequences of DNA such that complementary base pairing means they can displace eac
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jamessb
11y ago
The language is described in section V (p.26 onwards) of the supplementary materials of the paper: http://science.sciencemag.org/content/sci/suppl/2016/03/30/3...
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jamessb
11y ago
>Like all good developers, rather than attempt to build it myself, I had a good look around to see if anyone else had attempted the same thing, and it turns out, someone had. Unfortunately, the example I found isn’t open source, so we ha
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jamessb
11y ago
This isn't quite related to your question, but I think Markov chains made their debut in the original information theory paper by Shannon What? That paper even says: Stochastic processes of the type described above are known mathema
395.
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jamessb
11y ago
the breakthrough importance of markov chains i feel like i hear less and less about markov chains are they still in research and use? Markov chains will always be important, because they are a fairly fundamental concept (going back to t
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jamessb
11y ago
There were several watercolours, including the images above these captions: - "Francis Towne’s 1780 watercolour of a ruined tomb on the road from Rome signified the transience of human achievement (Credit: The Trustees of the British M
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jamessb
11y ago
There is a notion of an uninformative prior [0]. What would you do if you were studying a process that had not been previously studied, so you had no previous experience/data on which to base your a prior? If you wait, and choose a pri
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jamessb
11y ago
How so? The important parts to include on a sketch are that the function is monotonically increasing, has an asymptote at x=1 [0], intercepts the x-axis at x=e (approx 2.7) and quickly becomes almost flat. Both graphs agree on these points.
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jamessb
11y ago
But most of the people in the 'Research' departments of companies will have PhDs. For example, see the list of full-time positions at MSR [0]: both 'Researcher' positions require a PhD (Researcher - "Successful cand
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jamessb
11y ago
Dragon was sold to L&H, which had been engaging in fraud and went into brankrupcy; some of the technology was apparently sold to Visteon, some to ScanSoft (which then acquired Nuance, and took on its name). The founder, Jim Baker, lost
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jamessb
11y ago
IEEE Spectrum had a great series of interactive information graphics on 'Lessons from a decade of IT failures' [0]. In particular, "The Staggering Impact of IT Systems Gone Wrong" [1] and "Monuments to failure"
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jamessb
11y ago
A while ago I saw a paper in the SIAM Review - just one and a half pages of maths, followed by "Remark 2. The theorem proved here gives a completely new general method. It generalizes all known results for balancing chemical equation
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jamessb
11y ago
It's seems confused about who it is pitched at: the founder's personal site refers to it as "the tamagotchi for synthetic biology" [0]; but the main landing page [1] says that it enables "anyone to create and grow l
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jamessb
11y ago
The integrating separate pieces of lab equipment into one unit is reminiscent of the Bento Bio 'all in one' lab: http://www.bento.bio/bento-lab/ The bento lab looks more useful for teaching molecular biology:
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jamessb
11y ago
As written, the title is wrong, though the article does contain the correct statement that "Guinea worm disease is on the brink of becoming the second ever human disease to be completely eradicated through human endeavour". Rind
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jamessb
11y ago
They also do a lot of interesting work via Autodesk Research (including on some things you might not expect, such as synthetic biology): https://autodeskresearch.com/ Publication list: https://autodeskresearch.co
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jamessb
11y ago
Also Papers We Love: http://paperswelove.org/ https://github.com/papers-we-love/papers-we-love But I think these are papers written by Baker, rather than recommended by him.
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jamessb
11y ago
> To answer your question, financial e-mails are more likely to be mislabelled as personal than as professional, but not as often as it labels them correctly. Yes, but how likely is each mislabelling? There is no scale to indicate how t
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jamessb
11y ago
Fluid refuses to create a wrapper for a site using a self-signed SSL certificate (or at least, it did the last time I tried it). This was annoying, because I wanted to use it with an app I was self-hosting, and it wasn't worth the effo
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jamessb
11y ago
See also "The dashed line in use": http://www.nearfield.org/2006/09/the-dashed-line-in-use
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jamessb
11y ago
There have been several cases of hidden cameras filming guests at Airbnbs, prompting a blog post about a script to detect cameras and disconnect them from WiFi [0] that was posted here about a month ago [1]. 0: https://julianoliv
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jamessb
11y ago
Also, the cost of actually closing a station is not negligible. From the same article: Closing down a line is cumbersome. There must first be a transport appraisal analysing the effect of a closure on passengers, the environment and the ec
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jamessb
11y ago
Also AnyBar, which displays a coloured dot in the menu bar: https://github.com/tonsky/AnyBar Or TextBar, which is a $3 utility: http://www.richsomerfield.com/apps/
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jamessb
11y ago
The actual paper is: http://www.nature.com/nature/journal/v528/n7583/pdf/nature16...
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jamessb
11y ago
Michelle Vandy uses an Apple Trackpan on a tripod to control her MacBook. It's quite impressive to watch: https://www.youtube.com/watch?v=RAokWwilHGk "The last few years my arms have largely shaped my work setup.
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jamessb
11y ago
Expose looks very impressive, and was posted here 74 days ago: https://github.com/Jack000/Expose https://news.ycombinator.com/item?id=10376468
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jamessb
11y ago
There was some discussion when that PDF was posted here 3 weeks ago: https://news.ycombinator.com/item?id=10683778
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jamessb
11y ago
Wikipedia says yes: https://en.wikipedia.org/wiki/Tom_Duff
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jamessb
11y ago
For papers in 'general interest' or biological journals, the mathematical details necessary to understand what was actually done usually go in Supplementary Materials, rather than the paper itself: https://www.sciencema
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jamessb
11y ago
There is also a book publlished by O'Reilly, the Bad Data Handbook : http://shop.oreilly.com/product/0636920024422.do
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