i000

11 ms·

91.
by i000 11y ago
Circular RNAs are really "hot" these days. But, one should keep in mind that the amount of virtually all circular RNAs is lower in cancer (compared to non-cancerous adjacent normal tissue), thus they are not very promising as biom
92.
by i000 11y ago
A well established principal investigator said this to his lab during a crisis "we are out of money" meeting: "We are all in the same boat, but only I have a parachute"
93.
by i000 11y ago
Are you suggesting scientists are "goverment contractors"? Never thought of myself as one.
94.
by i000 11y ago
Certainly there are such scientists. There is a very strong incentive for researchers to be novel and make discoveries "out of the box" - how much of these discoveries will be published, and will stand the test of time is a very d
95.
by i000 11y ago
The absolute error-rate is not really a problem if the errors are random and you have the budget to sequence enough independent fragments. Sequencing becomes tricky (both Sanger and next-gen) because of non-random recurrent artifacts associ
96.
by i000 11y ago
Thousands of new life-science publications appear each day on PubMed. It is quite hard to keep up, but it is possible to set up: - keyword-triggered RSS-feeds at NCBI - an account on Google Scholar which has some "intelligent" not
97.
by i000 12y ago
> your peer group has even looked at this. I think it will help most if I explain the incentives for scientists (at least in the US). From their first day in the lab scientists are rewarded most for generating data and making discoveries
98.
by i000 12y ago
The cancer research and cancer epidemiology communities do not really talk to each other (as a cancer researcher for many years I have never been to an epidemiology seminar despite working in a 'cancer center'). So it is really a
99.
by i000 12y ago
Author of PaPy here. Thanks for giving PaPy a try. Although PaPy [ https://github.com/mcieslik-mctp/papy ] has never gained traction :(, I have been using it daily for over 5 years (no bugs in the scheduler so far). By n