ghc

25 ms·

331.
by ghc 6y ago
TFA complains about MongoDB and Lucene -- neither of which are RDBMSs -- having their own query language.
332.
by ghc 6y ago
And while we're at it, I don't want to learn your programming language. Everyone should just use Java for everything, FFS. /s Seriously, the idea that everything maps well onto relational databases is incredibly misplaced. No
333.
by ghc 6y ago
According to my wife, who is an immunologist working on this same mRNA tech, but applied to cancer, it also has promise in treating allergies -- both the food kind and the kind I have (animals).
334.
by ghc 6y ago
Yes. BioNTech are already into phase 1s and phase 2s with several others. My wife works on one of the programs targeting cancer, which has years of development and trials behind it.
335.
by ghc 6y ago
> Was going to respond that I recall the F-35 uses C++ AFAIK its critical flight systems are still in Ada, but it's a beast of a software platform. My company joined the effort last year and found that even our tiny area was an incr
336.
by ghc 6y ago
There's a large body of academic research on this, and many, many failures to learn from, including many that cost lives or cost hundreds of millions of dollars. In practice, there are lots and lots of bugs in any C program of any comp
337.
by ghc 6y ago
Closest I can think of is Purely Functional Data Structure (Chris Okasaki) or Category Theory for Programmers (Bartosz Milewski), but they're not exactly what you're after. I would submit that this paper from FB is more in the vei
338.
by ghc 6y ago
Haskell is good for correctness. Where correctness really matters, you might find Haskell. That makes it a very niche language, as most developers don't really care about correctness. But you do find Haskell in places where complexit
339.
by ghc 6y ago
Being a protectorate means by treaty the US has some responsibility for the military defense of Korea. https://www.americanforeignrelations.com/O-W/Protectorates-a...
340.
by ghc 6y ago
Contact us at jobs@sentenai.com .
341.
by ghc 6y ago
Sentenai | Multiple Roles | Remote (US) or Boston | Full-time | US citizens only Sentenai helps organizations make decisions at the speed of their data. Our data fusion platform uses autonomous data engineering to organize data from sensors
342.
by ghc 6y ago
Running any sort of innovative data infrastructure startup (whether data prep, database, data pipeline, etc.) is now an exercise in futility. The big three cloud providers will embrace your innovation, extend your product, and extinguish
343.
by ghc 6y ago
Unfortunately my wife leads a team coordinating R&D conversion to manufacturing so I have no idea what I can or cannot say that isn't on the website. But from my perspective the regulatory process is a lot easier to navigate than t
344.
by ghc 6y ago
BioNTech is different from a small biotech that can only produce drug candidates. They have their own advanced manufacturing plant and can take it end to end. Their US branch, which my wife is a part of, has all the in-house expertise neede
345.
by ghc 6y ago
I am curious how this compares to http://dataframe.ai or the open source metaframe ( http://github.com/rsyi/metaframe ) tools I've looked at in the past? It might be helpful to have more specific infor
346.
by ghc 6y ago
I would classify early web (1.0) as 1993-2003 (pre-AJAX), and modern web (2.0) as 2004-on (post-AJAX). The biggest change since then has been on the backend -- moving from web frameworks in Python/Ruby to Single Page Applications with
347.
by ghc 6y ago
Rails was popular before anyone ever heard of Django. Rails jobs were already common when it reached 1.0 at the end of 2005 (In early 2006 a law firm offered me $30 to do rails work as a summer job off campus). Django took another couple ye
348.
by ghc 6y ago
I just want to add my 2 cents in hope that it's helpful. I'm a co-founder/partner of a seed-stage VC fund and do keep track of the pitch decks we've seen as a partnership over the past two funds spanning six years. Compa
349.
by ghc 7y ago
Example of how "co-founding" a company with a VC can be a successful model: https://www.thirdrockventures.com/ The difference is Third Rock also sends tens of millions in cash, so...
350.
by ghc 7y ago
In weakening financial markets (no matter the cause), companies often stop stockpiling talent and employees perceived as overpaid relative to their value (as valued by contribution to revenue) are often let go. There have been large layoffs
351.
by ghc 7y ago
It's non-startups that are having the hardest time finding talent thanks to tech giants (also not startups) getting into bidding wars over talent. Startups are in general fine -- they can sell the "upside" that more establish
352.
by ghc 7y ago
No it implies that rapidly hiring FAANG divisions are so desperate for talent they're willing to outbid anyone else. One could call that a market, but it's a market distorted by a few tech companies that are far wealthier than the
353.
by ghc 7y ago
Wayfair is not and has never been your typical tech startup. The founders didn't even take VC or give out much equity until soon before their IPO. Given their conservative behavior, I'm not surprised they looked at the diminishing
354.
by ghc 7y ago
They paid us $600K every six months to analyze the data and suggest adjustments to their control systems (it's called continuous commissioning, but it's not really continuous due to laws in many places about requiring a person in
355.
by ghc 7y ago
There's a world outside of web apps and SV tech companies. There's a lot of big datasets out there, most of which never hit the cloud at all. Story time: I worked on one project where a single (large) building's internal se
356.
by ghc 7y ago
Fine print: But it might cost you $300K CapEx or $800K/yr OpEx. Hope you have a budget!
357.
by ghc 7y ago
I have one with 64GB and 1TB SSD. Running multiple linux VMs in WMWare Fusion right now and it's silent. The fans only really get loud when I'm compiling.
358.
by ghc 7y ago
Really sad. Hipmunk was something I loved and something that took a lot of pain out of my life.
359.
by ghc 7y ago
Yes, it happens. Deal flow is a common performance metric in funds so if you catch someone at the right time they will read it. You can't raise a whole round that way, but you can definitely get a meeting and leverage that for intros
360.
by ghc 7y ago
The insight I was trying to provide is that buying the list of emails from the list owner probably isn't worth it as it's not comprehensive. For my methodology, I sorted alphabetically and cross-referenced with our internal deal t

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