getoffmycase

7 ms·

31.
by getoffmycase 3y ago
I question a lot of the info in comment. Specifically the “humans domesticated themselves 6000years ago.” We had characteristics of “domesticating ourselves” long before 6000 years ago. Non-pronounced canines, reduced sexual dimorphism betw
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by getoffmycase 3y ago
In that case I think the “monetization” is in the form of misaligned incentives with scientific endeavors. The incentives are having a job, getting grants funded, and obtaining prestige.
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by getoffmycase 3y ago
It is an absolute nightmare. Biology is fundamentally fuzzy and our knowledge is incomplete. Biological actors, DNA and RNA and proteins, can act in surprising ways in feedback loops that are extremely difficult to track and quantify. Imagi
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by getoffmycase 3y ago
Scientists should not shut out other ideas for two decades even though there were serious challenges to the hypothesis the whole time. Part of being a good scientist is admitting your chosen hypothesis isn’t correct and that it’s time to cr
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by getoffmycase 3y ago
It is not better in natural sciences. Alzheimer’s disease treatment based on the amyloid plaque hypothesis being the prime example. Basically researchers closed ranks and doled out grant money disproportionately to the amyloid hypothesis re
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by getoffmycase 3y ago
There’s another alternative: conference talks have a higher signal to noise ratio than just pushing a paper out into the void (the background noise). To get a talk, you need to be selected, so that act of selection is the first filter. Afte
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by getoffmycase 3y ago
RNA is generally short lived. But specific kinds of RNA can have longer lifetimes. It’s accurate to say that RNA lifetime is extremely tightly regulated, and most of the time that means that it is short lived. Its lifetime is also extremely
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by getoffmycase 3y ago
It depends on temperature, pressure and other factors like salinity.
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by getoffmycase 3y ago
My lab codes in C# primarily. I love how I can easily prototype something quickly and then immediately transition to optimizing for speed. If I really need speed, the interop between C (and Fortran) and C# is super simple, and far easier to
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by getoffmycase 3y ago
The way ChatGPT writes drives me nuts in some specific ways. So I was messing around with it and asked it to specifically eliminate certain phrases it commonly uses, remove superfluous words, and modify the sentence structures in some spec
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by getoffmycase 4y ago
Really? My Apple rain predictions are nearly 0% accurate. It’s more of a “low level cloud” forecast more than anything else
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by getoffmycase 4y ago
This has to be an April Fool's day joke right?
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by getoffmycase 4y ago
Ginkgo Bioworks, Berkeley Lights. Although targeting biotech during the bubble was kinda like shooting fish in a barrel. Seems like a lot of barely concealed fraud got VC funding.
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by getoffmycase 4y ago
I work in a field where the training data is extremely sparse because labeled data is incredibly time consuming and labor intensive to come by. There’s ways to automate labeling, but I don’t really trust those methods fully cause I’ve seen
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by getoffmycase 4y ago
Thanks for putting the process of what I did twice in the last two days into clear, coherent words and logic.
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by getoffmycase 4y ago
I keep screaming into the void that the real issue is the poor risk management of the bank, but nobody in the echo chambers wants to listen to anything other than VC conspiracy points
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by getoffmycase 4y ago
I’m finishing my bioinformatics-centric PhD and I really resonated with the author’s sentiments. Except in the case of the bioinformatics field, I feel like there’s too much data for any person to make sense out of. And if you do anything b
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by getoffmycase 4y ago
This is the bane of my existence. I work in a lab that uses as close to industry standard coding practices that we can do with our current skeleton crew numbers (unit tests, CI, version control, unit tests, code quality standards and norms)
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by getoffmycase 4y ago
> products built on papers This is the key to everything else. There is built in reproducibility and amplification of new, functional ideas in the ML community. For the most part in life sciences, papers are published to achieve current
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by getoffmycase 4y ago
People care. A lot people care very deeply. The problem is that those whose care powerless and there is no incentive to fighting the system. If we try, we risk our careers.
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by getoffmycase 4y ago
The problem with S4 is that it really sucks to write.
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by getoffmycase 4y ago
Having looked at a large number of R packages source code, I do hesitate to freely label R packages as generally high-quality. I’ve been operating on the “trust, but verify” principle