Y
HN Search
Hacker News Search
new
|
comments
|
top
|
jobs
frisco
searching PlanetScale…
1.
▲
2.
▲
3.
▲
4.
▲
5.
▲
6.
▲
42 ms
·
391.
▲
by
frisco
14y ago
Menlo Park, CA Transcriptic: Core Developer or Automation Engineer Transcriptic is the "Amazon Web Services" for life sciences. Rather than carry out wet-lab experiments by hand, researchers can code up (or visually configure) their experi
392.
▲
by
frisco
14y ago
> This is pretty much all any executive does at any company with any scale. Totally false. They do allocate budget, but they also recruit, retain, and motivate the best staff members they can find. They proactively keep an eye on po
393.
▲
The Perfect Bagel Is Engineered in California
(wired.com)
1 points
by
frisco
14y ago
|
0 comments
394.
▲
by
frisco
14y ago
> This is the most powerful AI experiment yet conducted (publicly known). That's an ill-defined statement. AI is a vast and diverse field: what makes one demonstration more "powerful" than another? There are definitely other projects
395.
▲
by
frisco
14y ago
(Sorry rb2k_, I didn't mean to downvote you.)
396.
▲
A countdown timer has appeared at T-7 hours on Airtime.com
(airtime.com)
2 points
by
frisco
14y ago
|
0 comments
397.
▲
by
frisco
14y ago
Thiel is misinterpreting the increase in lifespan data. It's a famous dataset, but it's intepreted in terms of decreasing infant mortality -- not an increase in the average upper limits. Over the last couple hundred years, the average wes
398.
▲
by
frisco
14y ago
> "Question from audience: What keeps you guys up at night? What do you fear most? > Paul Graham: I fear that something will come along that causes me personally to have to do a lot more work. [ http://blakemasters.tumblr.com/p
399.
▲
by
frisco
14y ago
I actually don't think that advertising is Facebook's future. The intent isn't there in the same way it is with a Google search. However, I do think Facebook has a bright future with payments: imagine "Pay with Facebook" buttons throughou
400.
▲
by
frisco
14y ago
"Engine 5 shutdown: chamber pressure high" was the reason given on the web cast.
401.
▲
by
frisco
14y ago
File writes can be atomic. If it's left in a bad state, open vim and fix it.
402.
▲
by
frisco
14y ago
I don't think the DoJ would ever approve that.
403.
▲
by
frisco
14y ago
(That's a publication number, not a patent number. Notice that it starts with a year. Issued patent numbers are sequential.)
404.
▲
by
frisco
14y ago
I agree with you that it's not for anyone, other than the man in the arena, to determine whether someone belongs in a startup or not. At the same time, I strongly agree with the observations made by OP. The social pressure is strong in th
405.
▲
by
frisco
14y ago
Where are they getting the citation graph from? They hint at PubMed, but PubMed doesn't have it.
406.
▲
by
frisco
14y ago
Monthly.
407.
▲
by
frisco
14y ago
I have a couple of the xen instances, but the vast majority of my capacity is on colo'd machines and a managed dedicated box. My total hosting bill is in the $300-$400 range. Admittedly I haven't looked closely at EC2 reserved pricing (I
408.
▲
by
frisco
14y ago
I've been running a fair amount of infrastructure with them for a while now and I can't possibly recommend them highly enough. I remember there was a time a couple years ago when there was a queue to get a box with Luke. You have to know
409.
▲
by
frisco
15y ago
> we as computer scientists and programmers really don't (yet) have a good handle on what the "right" abstractions for big/monster data problems It's more that the underlying technologies aren't good enough to support these abstractions
410.
▲
by
frisco
15y ago
I didn't necessarily mean scalability in terms of just compute throughput; I was also talking about sustained productivity, though the two are related. Abstraction does let you build faster if done correctly, but in my experience I've neve
411.
▲
by
frisco
15y ago
While cool, and interesting, this strikes me as the exact type of overengineering tech-heavy startups kept being told to stop doing. I get the argument that it'll "give you a platform to build on" and help you "move fast later," but how mu
412.
▲
by
frisco
15y ago
Maybe nothing. But they're out there selling $150k in jellyfish a month on 50% margins, and probably having a blast doing it. Their potential market isn't exactly small. Not sure what else you're looking for.
413.
▲
by
frisco
15y ago
Not to take away from your main point, but Google did need to solve a fundamental computer science problem: how to compute eigenvector centrality efficiently. It would have been impossible to calculate PageRank at web scale without the P
414.
▲
by
frisco
15y ago
What are the limits to the vertical scaling? Can I, for example: dotcloud scale MYAPP db:memory=144G How much would such a thing cost, if possible?
415.
▲
by
frisco
15y ago
Here you go: http://www.ncbi.nlm.nih.gov/protein?db=protein&cmd=link&... GenBank for CD47: http://www.ncbi.nlm.nih.gov/protein/AAH37306.1 (Should be obvious, but this is woefully incomplete in terms of where CD47 probably actually
416.
▲
by
frisco
15y ago
First, there's a lot of bad science out there. A large part of this is due to the fact that animal models are almost uniformly terrible at modeling real human disease. Second, a therapy may be highly effective but also highly toxic or hav
417.
▲
by
frisco
15y ago
Wow. Extraordinary claims require extraordinary evidence, but Irv Weissman and his lab are the real deal. Here's the original article (which is open access): http://www.pnas.org/content/early/2012/03/20/1121623109 Of course, this isn't
418.
▲
The NSA's Yottabyte-scale Whole-Internet Capture Center in Utah
(wired.com)
6 points
by
frisco
15y ago
|
0 comments
419.
▲
by
frisco
15y ago
Clinton was nearly impeached for perjury, not the scandal itself. Unfortunately, the one bad thing Santorum doesn't appear to be is dishonest.
420.
▲
PayPal Here launched today, a direct — and triangular — competitor with Square
(venturebeat.com)
5 points
by
frisco
15y ago
|
1 comments
More ›